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T14489Azvudine;化合物AzvudineFNC|||RO-0622;4-氨基-1-(4-C-叠氮基-2-脱氧-2-氟-BETA-D-呋喃阿拉伯糖基)-2(1H)-嘧啶酮|||FNC|||RO-0622
Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM).
价 格:¥电议型 号:T14489产 地:中国大陆
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T14462Azido-PEG5-NHS ester;化合物 T14462Azido-PEG5-NHS ester
Azido-PEG5-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14462产 地:中国大陆
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T14381AZD7624;化合物AZD7624AZD-7624;AZD-7624
AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.
价 格:¥电议型 号:T14381产 地:中国大陆
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T14362LAY 9944 dihydrochloride;化合物AY 9944 盐酸盐AY 9944 dihydrochloride
AY 9944 dihydrochloride is a intermediate.
价 格:¥电议型 号:T14362L产 地:中国大陆
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T14362AY 9944;化合物AY 9944AY 9944
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol[1][2][3]. AY 9944 causes hypocholesterolemia and accumulation of 7DHC.
价 格:¥电议型 号:T14362产 地:中国大陆
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T1434Clarithromycin;克拉霉素A-56268;A-56268|||克拉霉素
Clarithromycin (A-56268) is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor. The chemical classification of clarithromycin is Macrolides.
价 格:¥电议型 号:T1434产 地:中国大陆
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T14262Aminooxy-PEG2-azide;化合物 T14262Aminooxy-PEG2-azide
Aminooxy-PEG2-azide is a PEG-based PROTAC linker utilized for the synthesis of PROTACs[1], as well as a non-cleavable 2-unit PEG ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[2].
价 格:¥电议型 号:T14262产 地:中国大陆
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T1419Azithromycin hydrate;阿奇霉素二水合物CP-62993 dihydrate|||Azithromycin dihydrate;CP-62993 dihydrate|||阿奇霉素二水
Azithromycin hydrate (CP-62993 dihydrate) is a semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.
价 格:¥电议型 号:T1419产 地:中国大陆
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T14162Ald-Ph-amido-C2-PEG2-amine;化合物 T14162Ald-Ph-amido-C2-PEG2-amine
Ald-Ph-amido-C2-PEG2-amine is a polyethylene glycol (PEG)-based linker utilized for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].
价 格:¥电议型 号:T14162产 地:中国大陆
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T14127Adenosine A1 receptor activator T62;化合物Adenosine A1 receptor activator T62Adenosine A1 receptor acti
Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].
价 格:¥电议型 号:T14127产 地:中国大陆
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T14068A-192621;化合物 T14068A-192621
A-192621 is a potent, nonpeptide, orally active and selective endothelin B (ETB) receptor antagonist with an IC50 of 4.5 nM and a Ki of 8.8 nM. A-192621 promotes apoptosis in PASMCs and it also causes elevation of arterial blood pressure and an elevation in the plasma ET-1 level[1][2][3]. The selectivity of A-192621 is 636-fold higher than ETA (IC50 of 4280 nM and Ki of 5600 nM).
价 格:¥电议型 号:T14068产 地:中国大陆
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T140626"-O-Acetylgenistin;化合物 T140626"-O-Acetylgenistin|||6" O Acetylgenistin|||6"OAcetylgenistin;6"-O-Ace
6-O-Acetylgenistin is an isoflavone glycoside isolated from soybeans. 6-O-Acetylgenistin significantly inhibits lipid peroxidation in rat liver microsome with an IC50 of 10.6 μM[1][2].
价 格:¥电议型 号:T14062产 地:中国大陆
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T140162-Hydroxyethyl disulfide mono-tosylate;化合物 T140162-Hydroxyethyl disulfide mono-tosylate
2-Hydroxyethyl disulfide mono-tosylate is a cleavable linker compound employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14016产 地:中国大陆
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T13962Volemitol;化合物 T13962D-Volemitol;D-Volemitol
Volemitol is a seven-carbon sugar alcohol that fulfills several important physiological functions in certain species of the genus Primula.
价 格:¥电议型 号:T13962产 地:中国大陆
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T13887SJF620;化合物 T13887SJF620
SJF620 is a potent degrader of PROTAC BTK(DC50 : 7.9 nM).
价 格:¥电议型 号:T13887产 地:中国大陆
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T13862LRecilisib sodium;化合物 T13862LBrand name: Ex-RAD|||ON 01210.Na|||ON01210|||ON-01210;Brand name: Ex-RAD
Recilisib, also known as ON 01210.Na, is a radioprotectant, which modifys cell cycle distribution patterns in cancer cells subjected to radiation therapy, and it has been identified as a potential candidate for radiation protection studies. It appears that Recilisib radioprotective mechanisms involve prevention of p53-dependent and independent radiation-induced apoptosis.
价 格:¥电议型 号:T13862L产 地:中国大陆
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T13862Recilisib;RECILISIB 钠盐Ex-RAD|||ON 01210;RECILISIB 钠盐|||Ex-RAD|||ON 01210
Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.
价 格:¥电议型 号:T13862产 地:中国大陆
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T13809P62-mediated mitophagy inducer;化合物P62-mediated mitophagy inducerPMI;PMI
P62-mediated mitophagy inducer (PMI) is a regulator of mitophagy .
价 格:¥电议型 号:T13809产 地:中国大陆
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T13762Luteolin 7-sulfate;木犀草素-7-硫酸酯Luteolin 7-sulfate
Luteolin 7-sulfate, derived from the marine plant Phyllospadix iwatensis Makino, suppresses TYR gene expression by intervening in a signaling pathway involving the cAMP-responsive element binding protein (CREB) and microphthalmia-associated transcription factor (MITF). This inhibition ultimately leads to a decrease in melanin synthesis.
价 格:¥电议型 号:T13762产 地:中国大陆
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T13759LTX-401 dihydrochloride (1262851-70-6 free base);化合物 T13759LTX-401 dihydrochloride;LTX-401 dihydroch
LTX-401, targets the Golgi apparatus, and is an oncolytic amino acid derivative.
价 格:¥电议型 号:T13759产 地:中国大陆