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T10743CDK9-IN-11;化合物 T10743CDK9-IN-11
CDK9-IN-11 is a potent CDK9 inhibitor that is the ligand for the PROTAC CDK9 Degrader-1 [1].
价 格:¥电议型 号:T10743产 地:中国大陆
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T10742CDK9-IN-10;化合物CDK9-IN-10CDK9-IN-10
CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.
价 格:¥电议型 号:T10742产 地:中国大陆
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T10741CDK9-IN-1;化合物 T10741CDK9-IN-1
CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection (IC50: 39 nM for CDK9/CycT1).
价 格:¥电议型 号:T10741产 地:中国大陆
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T10740CDK8-IN-1;化合物CDK8-IN-1CDK8-IN-1
CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).
价 格:¥电议型 号:T10740产 地:中国大陆
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T10737CDK4/6-IN-3;化合物 T10737CDK4/6-IN-3
CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM) used for the treatment of glioblastoma. It inhibits CDK1 with a Ki of 110 nM.
价 格:¥电议型 号:T10737产 地:中国大陆
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T10735CDK4/6/1 Inhibitor;CDK4/6/1抑制剂Crozbaciclib;Crozbaciclib
CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM). CDK4/6 inhibitor is a class of compounds used for the treatment of some types of hormone receptor positive, HER2-negative breast cancer, which can block the process of breast cancer cell division and reproduction.
价 格:¥电议型 号:T10735产 地:中国大陆
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T10734CDK ligand for PROTAC;化合物 T10734CDK ligand for PROTAC
CDK ligand for PROTAC is a CDK inhibitor with antitumor activity. It has been used to design PROTAC CDK4/6 degraders.
价 格:¥电议型 号:T10734产 地:中国大陆
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T10733CDDO-EA;化合物CDDO-EATP319|||CDDO ethyl amide|||RTA 405;TP319|||CDDO ethyl amide|||RTA 405
CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.
价 格:¥电议型 号:T10733产 地:中国大陆
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T10726Cdc7-IN-4;化合物 T10726Cdc7-IN-4
Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.
价 格:¥电议型 号:T10726产 地:中国大陆
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T10724Cdc7-IN-1;化合物 T10724Cdc7-IN-1
Cdc7-IN-1 is a highly selective and ATP competitive inhibitor of Cdc7 kinase (IC50: 0.6 nM at 1 mM ATP). It potently inhibits Cdc7 activity in cancer cells and effectively induces cell death.
价 格:¥电议型 号:T10724产 地:中国大陆
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T10718LCCT241533 hydrochloride;化合物 T10718LCCT241533 hydrochloride
CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
价 格:¥电议型 号:T10718L产 地:中国大陆
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T10718CCT241533;化合物 T10718CCT241533
CCT241533 is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
价 格:¥电议型 号:T10718产 地:中国大陆
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T10714CCR5 antagonist 1;化合物 T10714CCR5 antagonist 1
CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.
价 格:¥电议型 号:T10714产 地:中国大陆
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T10713CCR4 antagonist 2;化合物 T10713CCR4 antagonist 2
CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. CCR4 antagonist 2 (Compound 31) exhibits IC50 values of Ca2+flux and (chemotaxis) CTX are 40 nM and 70 nM, respectively.
价 格:¥电议型 号:T10713产 地:中国大陆
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T10705CCG 203769;化合物CCG 2037694-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione|||RGS4 inhibitor 11b|||Thiad
CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.
价 格:¥电议型 号:T10705产 地:中国大陆
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T10704CCB02;化合物CCB02CCB02
CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-related kinases, or the phosphorylation status of Aurora-A, CDK2, Plk1, Plk2, and CHK1.
价 格:¥电议型 号:T10704产 地:中国大陆
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T10703Mezigdomide;化合物 MezigdomideCC-92480;CC-92480
Mezigdomide (CC-92480) is a potent, novel, selective and active cereblon E3 ubiquitin ligase modulator (CELMoD) that often acts as a molecular glue. Mezigdomide has antimyeloma activity.
价 格:¥电议型 号:T10703产 地:中国大陆
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T10694CB1 inverse agonist 1;化合物CB1 inverse agonist 1MRL-650;MRL-650
CB1 inverse agonist 1 (MRL-650) is an orally active and selective CB1 agonist. The IC50s for CB1 and CB2 are 7.5 nM and 4100 nM, respectively. CB1 inverse agonist 1 shows anorexigenic effects.
价 格:¥电议型 号:T10694产 地:中国大陆
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T10693CB-6644;化合物CB-6644CB-6644
CB-6644 is a selective inhibitor of the RUVBL1/2 complex and blocks the ATPase activity of RUVBL1/2 (IC50 = 15 nM).
价 格:¥电议型 号:T10693产 地:中国大陆
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T10686Carvedilol metabolite 4-Hydroxyphenyl Carvedilol;化合物 T106864-Hydroxyphenyl Carvedilol|||4-Hydroxycar
4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol. Carvedilol is a beta-blocker/alpha-1 blocker.
价 格:¥电议型 号:T10686产 地:中国大陆