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产品数:86101
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T10594bpV(phen);化合物 T10594bpV(phen)
bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).
价 格:¥电议型 号:T10594产 地:中国大陆
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T10592BPR1K871;化合物 T10592DBPR114;DBPR114
BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values of 19 nM and 22 nM, respectively.
价 格:¥电议型 号:T10592产 地:中国大陆
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T10590Zatolmilast;化合物BPN14770BPN14770;BPN14770
Zatolmilast (BPN14770) is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).
价 格:¥电议型 号:T10590产 地:中国大陆
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T10589BPN-15606 besylate (1914989-49-3 free base);化合物 T10589BPN-15606 besylate;BPN-15606 besylate
BPN-15606 besylate is a highly potent, orally active γ-secretase modulator, attenuates the production of Aβ40 and Aβ42 by SHSY5Y neuroblastoma cells (IC50s: 7 nM and 17nM).
价 格:¥电议型 号:T10589产 地:中国大陆
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T10586LBPH-1358;化合物BPH-1358NSC50460;NSC50460
BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL)[1][2].
价 格:¥电议型 号:T10586L产 地:中国大陆
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T10586BPH-1358 free base;化合物 T10586NSC50460 free base;NSC50460 free base
BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng/mL).
价 格:¥电议型 号:T10586产 地:中国大陆
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T10584Bovinic acid;9Z,11E十八碳二烯酸(9Z,11E)-Octadecadienoic acid|||Rumenic acid;(9Z,11E)-Octadecadienoic acid|
Bovinic acid ((9Z,11E)-Octadecadienoic acid) is a conjugated linoleic acid with anticancer and anti-atherosclerotic activity and can be used to study coronary heart disease and obesity in the elderly.
价 格:¥电议型 号:T10584产 地:中国大陆
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T10581Boc-MLF TFA (67247-12-5 free base);化合物 T10581Boc-Met-Leu-Phe-OH (TFA)|||Boc-MLF TFA;Boc-Met-Leu-Phe-
Boc-MLF (TFA) is a specific antagonist of formyl peptide receptor (FPR) and also inhibits signaling through FPRL1 at higher concentrations.
价 格:¥电议型 号:T10581产 地:中国大陆
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T10580BOC-D-FMK;3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯BOC-D-FMK
Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).
价 格:¥电议型 号:T10580产 地:中国大陆
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T1058Carboplatin;卡铂NSC 241240|||CBDCA|||JM-8;NSC 241240|||卡铂|||CBDCA|||JM-8
Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor. Carboplatin binds to DNA, inhibits replication and transcription, and induces cell death. Carboplatin has antitumor activity.
价 格:¥电议型 号:T1058产 地:中国大陆
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T10579BO3482;化合物 T10579BO3482
BO3482 is an antimicrobial compound and can inhibit the growth of methicillin-resistant Staphylococci (MIC90: 6.25 mg/mL).
价 格:¥电议型 号:T10579产 地:中国大陆
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T10576BMY-43748;化合物 T10576BMY-43748
BMY-43748 is an antibacterial compound with great in vitro and in vivo antibacterial activity.
价 格:¥电议型 号:T10576产 地:中国大陆
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T10574BMVC;化合物 T10574BMVC
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase (IC50: ~2.5 μM).
价 格:¥电议型 号:T10574产 地:中国大陆
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T10573BMT-145027;化合物BMT-145027BMT-145027
BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).
价 格:¥电议型 号:T10573产 地:中国大陆
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T10572LBMT-124110 Formate;BMT-124110甲酸盐BMT-124110 Formate(1679371-59-5 Free base);BMT-124110 Formate(167937
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM.
价 格:¥电议型 号:T10572L产 地:中国大陆
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T10572BMT-124110;化合物BMT-124110BMT-124110
BMT-124110 is a selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibited BMP-2 induced protein kinase BIKE with IC50 of 17 nM. BMT-090605 inhibits cyclin G-associated kinase GAK with an IC50 of 99 nM.
价 格:¥电议型 号:T10572产 地:中国大陆
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T10569BMS-654457;化合物 T10569BMS-654457
BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).
价 格:¥电议型 号:T10569产 地:中国大陆
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T10568BMS-470539 dihydrochloride;化合物 T10568BMS-470539 dihydrochloride
BMS-470539 dihydrochloride is a highly potent and selective agonist of the melanocortin-1 receptor (MC-1R; IC50: 120 nM; EC50: 28 nM) with anti-inflammatory properties. It does not activate MC-3R and is a very weak partial agonist at MC-4R and MC-5R.
价 格:¥电议型 号:T10568产 地:中国大陆
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T10567BMS-214662;化合物 T10567BMS-214662
BMS-214662 is a potent and selective farnesyl transferase inhibitor that induces mitochondrial apoptosis in primitive CD34+ chronic myeloid leukemia (CML) stem cells/progenitors, and has the ability to selectively target CML stem cells/progenitors with antitumor activity.
价 格:¥电议型 号:T10567产 地:中国大陆
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T10564(8R,9S)-Talazoparib;他拉唑帕利 (8R,9S)(8R,9S)-BMN-673;(8R,9S)-BMN-673|||他拉唑帕利 (8R,9S)
(8R,9S)-Talazoparib is Talazoparib enantiomer , less active than Talazoparib on the inhibition of PARP1 (IC50: 144 nM).
价 格:¥电议型 号:T10564产 地:中国大陆