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T104985-HT2A antagonist 1;化合物 T104985-HT2A antagonist 1
5-HT2A antagonist 1 is a 5-HT2A antagonist. It may be useful in the treatment of gastrointestinal disorders circulatory disorders.
价 格:¥电议型 号:T10498产 地:中国大陆
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T10497Benralizumab贝那利珠单抗BIW-8405|||MEDI-563
Benralizumab (MEDI-563) is a monoclonal antibody targeting the interleukin-5 receptor alpha (IL-5Rα). It enhances antibody-dependent cell-mediated cytotoxicity, leading to a rapid depletion of eosinophils. Benralizumab is used for severe eosinophilic asthma and can be employed to prevent exacerbations of chronic obstructive pulmonary disease.
价 格:¥电议型 号:T10497产 地:中国大陆
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T10496Bencianol;苯西阿诺ZY15051;ZY15051|||苯西阿诺
Bencianol is a semisynthetic flavonoid with anti-spasmogenic activities.
价 格:¥电议型 号:T10496产 地:中国大陆
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T10495LBefiradol化合物 T10495LNLX-112|||F13640
Befiradol (NLX-112) is an agonist of 5-HT1A receptor.
价 格:¥电议型 号:T10495L产 地:中国大陆
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T10494Beclomethasone 17-propionate;化合物 T10494Beclomethasone-17-monopropionate|||17-BMP;Beclomethasone-17-m
Beclomethasone 17-propionate is an active metabolite of Beclomethasone dipropionate and an agonist of the glucocorticoid receptor (GR). It exhibits greater affinity for GR than Beclomethasone dipropionate. Beclomethasone 17-propionate effectively suppresses cytokine production in COPD lung macrophages.
价 格:¥电议型 号:T10494产 地:中国大陆
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T10493Beclabuvir;贝拉布韦BMS-791325;BMS-791325
Beclabuvir (BMS-791325) is a potent NS5A replication complex inhibitor that inhibits the activity of the NS5B protein expressed by HCV genotypes 1, 2, 4, and 5 and is used in the study of HCV infection.
价 格:¥电议型 号:T10493产 地:中国大陆
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T10492BD-AcAc 2化合物BD-AcAc 2Ketone Ester
BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones. BD-AcAc 2 can elevate plasma levels of acetoacetate and β-hydroxybutyrate, blood Na+, blood glucose levels and blood creatinine levels after oral administration in mice. BD-AcAc 2 can partly prevent muscle weakness in septic mice. BD-AcAc 2 exhibits potential to improve endurance and exercise performance in animal body. BD-AcAc 2 can also be used to research diabetes or Parkinson’s disease.
价 格:¥电议型 号:T10492产 地:中国大陆
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T10491LGalidesivir hydrochloride;化合物 T10491LBCX 4430 hydrochloride|||Immucillin-A hydrochloride;BCX 4430 hy
Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp.
价 格:¥电议型 号:T10491L产 地:中国大陆
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T10491Galidesivir;加利司韦BCX4430|||Immucillin-A;BCX4430|||Immucillin-A
Galidesivir (BCX4430) is a broad-spectrum antiviral compound, an adenosine analog that inhibits viral RNA-dependent RNA polymerase (RdRp) activity.Galidesivir inhibits a wide range of RNA viral pathogens in vitro, and reduces lung infections in infected animals.
价 格:¥电议型 号:T10491产 地:中国大陆
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T10490(S)-ML753286;化合物 T10490(S)-ML753286
(S)-ML753286 is a breast cancer resistance protein (BCRP) inhibitor (IC50: 0.6 μM on BCRP efflux transporter).
价 格:¥电议型 号:T10490产 地:中国大陆
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T1049Oxybutynin chloride;盐酸奥昔布宁Oxybutynin hydrochloride|||Oxybutynin HCl;Oxybutynin hydrochloride|||盐酸奥昔布
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.
价 格:¥电议型 号:T1049产 地:中国大陆
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T10489BCR-ABL-IN-2;化合物 T10489BCR-ABL-IN-2
BCR-ABL-IN-2 is a BCR-ABL1 tyrosine kinase inhibitor (IC50s: 57 nM, 773 nM for ABL1 native and ABL1 T315I).
价 格:¥电议型 号:T10489产 地:中国大陆
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T10488BCR-ABL-IN-1;化合物 T10488BCR-ABL-IN-1
BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.
价 格:¥电议型 号:T10488产 地:中国大陆
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T10487BCL6-IN-3;化合物BCL6-IN-3BCL6-IN-3
BCL6-IN-3 is a potent BCL6 inhibitor with GI50 of 70 nM in SU-DHL4 cells. BCL6-in-3 regulates cell activation, differentiation, DNA damage and apoptosis, and has antitumor activity.
价 格:¥电议型 号:T10487产 地:中国大陆
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T10486LBCI hydrochloride化合物 T10486L(E)-BCI hydrochloride
BCI hydrochloride specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI hydrochloride does not inhibit DUSP5. BCI hydrochloride is an allosteric inhibitor of dual specificity phosphatase (DUSP).
价 格:¥电议型 号:T10486L产 地:中国大陆
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T10486BCI;化合物BCI(E)-BCI;(E)-BCI
BCI ((E)-BCI) is an allosteric inhibitor of dual-specificity phosphatase (DUSP; EC50s: 13.3 and 8.0 μM for DUSP6 and DUSP1 in cells) and does not inhibit DUSP5.
价 格:¥电议型 号:T10486产 地:中国大陆
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T10485PROTAC Bcl2 degrader-1;化合物 T10485PROTAC Bcl2 degrader-1
PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM).
价 格:¥电议型 号:T10485产 地:中国大陆
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T10484BCL2-IN-1;化合物 T10484BCL2-IN-1
BCL2-IN-1 is a potent Bcl-2 inhibitor (Ki <0.01 nM).
价 格:¥电议型 号:T10484产 地:中国大陆
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T10483Lisaftoclax;化合物LisaftoclaxBcl-2/Bcl-xl inhibitor 1|||APG-2575;Bcl-2/Bcl-xl inhibitor 1|||APG-2575
Lisaftoclax (Bcl-2/Bcl-xl inhibitor 1) is an oral dual inhibitor of Bcl-2 and Bcl-xl, with IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. Lisaftoclax is used to treat chronic lymphocytic leukemia (CLL) by inhibiting the action of the BCL-2 protein, which promotes the death of leukemia cells.
价 格:¥电议型 号:T10483产 地:中国大陆
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T10482LBB-Cl-Amidine hydrochloride化合物 T10482LBB-Cl-Amidine hydrochloride (1802637-39-3 free base)
BB-Cl-Amidine hydrochloride is an inhibitor of peptidylarginine deminase (PAD) [1].
价 格:¥电议型 号:T10482L产 地:中国大陆