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T10465Atuveciclib S-Enantiomer;化合物 T10465BAY-1143572 S-Enantiomer;BAY-1143572 S-Enantiomer
Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) is the (S)-enantiomer of BAY-1143572. Atuveciclib S-Enantiomer is a potent and selective CDK9 inhibitor, which inhibits CDK9 / CycT1 with an IC 50 of 16 nM.
价 格:¥电议型 号:T10465产 地:中国大陆
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T10464LAtuveciclib Racemate;阿维西利BAY-1143572 Racemate;BAY-1143572 Racemate|||阿维西利
Atuveciclib Racemate (BAY-1143572 Racemate) is the racemate mixture of Atuveciclib, which is a potent and highly selective, oral P-TEFb/CDK9 inhibitor which supresses CDK9/CycT1 with an IC50 of 13 nM.
价 格:¥电议型 号:T10464L产 地:中国大陆
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T10464Atuveciclib;化合物 T10464BAY-1143572;BAY-1143572
Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb / CDK9 inhibitor that inhibits CDK9 / CycT1 with an IC 50 of 13 nM [1].
价 格:¥电议型 号:T10464产 地:中国大陆
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T10463LBax inhibitor peptide V5 acetate;化合物T10463LBax inhibitor peptide V5 acetate(579492-81-2 free base);B
Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.
价 格:¥电议型 号:T10463L产 地:中国大陆
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T10463Bax inhibitor peptide V5;化合物 T10463BIP-V5|||BAX Inhibiting Peptide V5;BIP-V5|||BAX Inhibiting Peptid
Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor with anticancer activity.
价 格:¥电议型 号:T10463产 地:中国大陆
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T10462LBavisant dihydrochloride hydrate;化合物 T10462LJNJ31001074AAC;JNJ31001074AAC
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1 mg/day, 3 mg/day and 10 mg/day groups, respectively; the change in the 10 mg/day group
价 格:¥电议型 号:T10462L产 地:中国大陆
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T10462Bavisant dihydrochloride;化合物 T10462Bavisant dihydrochloride
Bavisant (JNJ-310010740) dihydrochloride is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition.
价 格:¥电议型 号:T10462产 地:中国大陆
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T10461Batimastat sodium salt;化合物 T10461BB-94 sodium salt;BB-94 sodium salt
Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).
价 格:¥电议型 号:T10461产 地:中国大陆
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T10460Batabulin;巴他布林T138067;巴他布林|||T138067
Batabulin (T138067) is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to cell-cycle arrest ultimately induce apoptotic cell death.
价 格:¥电议型 号:T10460产 地:中国大陆
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T1046Mexiletine hydrochloride;盐酸美西律KOE-1173 (hydrochloride)|||Mexiletine HCl|||KO1173;KOE-1173 (hydrochlo
Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myocardial cells, thereby reducing the rise rate of cardiac action potential (phase 0) and reducing the automaticity of Purkinje fibers.
价 格:¥电议型 号:T1046产 地:中国大陆
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T10459Banoxantrone dihydrochloride;巴诺蒽醌盐酸盐Banoxantrone|||Banoxantrone dihydrochloride|||Banoxantrone|||AQ4
Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.
价 格:¥电议型 号:T10459产 地:中国大陆
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T10458Banoxantrone (D12);化合物 T10458Banoxantrone (D12)|||Banoxantrone D12|||Banoxantrone (D-12)|||Banoxantr
Banoxantrone D12 (AQ4N D12) is the deuterium-labeled Banoxantrone. Banoxantrone is a bioreductive agent that can be reduced to a stable, DNA-affinity compound AQ4, which is a topoisomerase II inhibitor.
价 格:¥电议型 号:T10458产 地:中国大陆
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T10457BAN ORL 24;化合物 T10457BAN ORL 24
BAN ORL 24 is a potent and selective NOP receptor antagonist (IC50s: 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors).
价 格:¥电议型 号:T10457产 地:中国大陆
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T10456Bamaluzole;巴马鲁唑Bamaluzole
Bamaluzole is an agonist of GABA receptor.
价 格:¥电议型 号:T10456产 地:中国大陆
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T10455Bafilomycin B1巴佛洛霉素 B1巴佛洛霉素 B1
Bafilomycin B1, a macrolide antibiotic isolated from Streptomyces sp, acts as an inhibitor of K+-dependent ATPase of E. coli. It also inhibits Gram-positive bacteria and fungi.
价 格:¥电议型 号:T10455产 地:中国大陆
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T10454Bactenecin;抗菌肽Bactenecin, bovine;抗菌肽|||Bactenecin, bovine
Bactenecin is a cyclic antimicrobial peptide isolated from bovine neutrophils with potent activity against Bacterial and Fungal species.
价 格:¥电议型 号:T10454产 地:中国大陆
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T10453BACE1-IN-5;化合物 T10453BACE1-IN-5
BACE1-IN-5 (Compound 15), a potent β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, demonstrates significant efficacy with an IC50 of 9.1 nM for BACE1 inhibition and an impressive IC50 of 0.82 nM against cellular amyloid-β (Aβ) production. Additionally, it is engineered to enhance hERG inhibition and P-gp efflux, indicating its optimized medicinal chemistry profile [1].
价 格:¥电议型 号:T10453产 地:中国大陆
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T10452BACE1-IN-4;化合物 T10452BACE1-IN-4
BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.
价 格:¥电议型 号:T10452产 地:中国大陆
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T10451BACE1-IN-2;化合物 T10451BACE1-IN-2
BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).
价 格:¥电议型 号:T10451产 地:中国大陆
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T10450BACE1-IN-1;化合物 T10450BACE1-IN-1
BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).
价 格:¥电议型 号:T10450产 地:中国大陆