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T1045Trimipramine maleate;三甲丙咪嗪马来酸盐Surmontil maleate;Surmontil maleate|||马来酸三甲丙咪嗪|||三甲丙咪嗪马来酸盐
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Maleate is the maleate salt form of trimipramine, a tricyclic secondary amine of the dibenzazepine class, with an antidepressant property.
价 格:¥电议型 号:T1045产 地:中国大陆
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T10449BACE-1 inhibitor 1;化合物 T10449BACE-1 inhibitor 1
BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).
价 格:¥电议型 号:T10449产 地:中国大陆
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T10448LBacampicillin hydrochloride;盐酸巴氨西林Bacampicillin hydrochloride
Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.
价 格:¥电议型 号:T10448L产 地:中国大陆
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T10448Bacampicillin;巴氨西林Bacampicillin
Bacampicillin is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.
价 格:¥电议型 号:T10448产 地:中国大陆
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T10447BAA473;化合物 T10447BAA473
BAA473 is a bile acid analog that is a potent activator of the pyrin inflammasome. BAA473 can induce secretion of interleukin-18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial cells [1].
价 格:¥电议型 号:T10447产 地:中国大陆
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T10446BA-53038B;化合物 T10446BA-53038B
BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).
价 格:¥电议型 号:T10446产 地:中国大陆
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T10445B220;化合物B220B220
B220, an antiviral agent, inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV).
价 格:¥电议型 号:T10445产 地:中国大陆
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T10444TAK1/MAP4K2 inhibitor 1;化合物 T10444TAK1/MAP4K2 inhibitor 1
TAK1/MAP4K2 inhibitor 1 is a potent dual inhibitor of TGFβ-activated kinase 1 (TAK1) and MAP4K2 (IC50s: 41.1 nM and 18.2 nM).
价 格:¥电议型 号:T10444产 地:中国大陆
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T10443Aβ42-IN-1 free base;化合物 T10443Aβ42-IN-1 free base
Aβ42-IN-1 free base (compound 1v), an orally active γ-secretase modulator with high brain exposure, effectively lowers Aβ42 levels, exhibiting an IC 50 of 0.091 μM, and significantly diminishes brain Aβ42 levels in mice. Given these properties, Aβ42-IN-1 free base represents a potential disease-modifying agent for Alzheimer’s disease [1].
价 格:¥电议型 号:T10443产 地:中国大陆
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T10442A 83-01 sodium salt;化合物 T10442A 83-01 sodium salt
A 83-01 sodium salt is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC 50 s of 12 nM, 45 nM and 7.5 nM against the ALK5, ALK4 and ALK7 induced transcription, respectively [1].
价 格:¥电议型 号:T10442产 地:中国大陆
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T10441Azosemide;阿佐酰胺Azosemide
Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246??M and 0.197??M for hNKCC1A and NKCC1B).
价 格:¥电议型 号:T10441产 地:中国大陆
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T10440Azilsartan-d5;化合物 T10440TAK-536 D5;TAK-536 D5
Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.
价 格:¥电议型 号:T10440产 地:中国大陆
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T1044Clopidol;氯羟吡啶WR-61112;氯吡多|||氯羟吡啶|||WR-61112
Clopidol (WR-61112) is a very effective anticoccidial agent used in poultry.
价 格:¥电议型 号:T1044产 地:中国大陆
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T10439Azelnidipine D7;化合物 T10439CS-905 D7;CS-905 D7
Azelnidipine D7 is a deuterium-labeled Azelnidipine. Azelnidipine is an L-type calcium channel blocker.
价 格:¥电议型 号:T10439产 地:中国大陆
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T10438AZD 4407;化合物 T10438ZD 4407;ZD 4407
AZD 4407 is a potent inhibitor of 5-lipoxygenase.
价 格:¥电议型 号:T10438产 地:中国大陆
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T10437AZD8848;化合物 T10437AZD8848
AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.
价 格:¥电议型 号:T10437产 地:中国大陆
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T10436LAZD4573 HCl (2057509-72-3 free base);化合物 T10436LAZD4573 hydrochloride|||AZD4573|||AZD4573 HCl|||AZD-
AZD-4573 is a selective and short-acting inhibitor of the serine/threonine cyclin-dependent kinase 9, the catalytic subunit of the RNA polymerase II elongation factor positive transcription elongation factor b. It also has a potential antineoplastic activity.
价 格:¥电议型 号:T10436L产 地:中国大陆
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T10436AZD4573;化合物AZD4573AZD4573
AZD4573 is an effective and selective CDK9 inhibitor (IC50: <4 nM). It enables transient target engagement for the treatment of hematologic malignancies.
价 格:¥电议型 号:T10436产 地:中国大陆
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T10435Linaprazan;利那拉生AZD0865;利那拉生|||AZD0865
Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.
价 格:¥电议型 号:T10435产 地:中国大陆
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T10434AZD-5991;化合物 T10434AZD-5991
AZD-5991 is a potent and selective Mcl-1 inhibitor (IC50: 0.7 nM in FRET assay; Kd: 0.17 nM in SPR assay).
价 格:¥电议型 号:T10434产 地:中国大陆