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T10343AOH1160;化合物AOH1160N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide;N-(2-Oxo-2-(2-phenoxyphenyla
AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA). AOH1160 induces apoptosis and causes cell-cycle arrest by interfering with DNA replication.
价 格:¥电议型 号:T10343产 地:中国大陆
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T10342Antitumor agent-2;抗肿瘤剂2Antitumor agent-2
Antitumor agent-2 has anti-inflammatory and anti-tumor activity and can be used to study cancer.
价 格:¥电议型 号:T10342产 地:中国大陆
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T10341Antitumor agent-19;化合物Antitumor agent-19Antitumor agent-19
Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.
价 格:¥电议型 号:T10341产 地:中国大陆
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T10340Antitrypanosomal agent 2;抗锥体虫剂2Antitrypanosomal agent 2
Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei.
价 格:¥电议型 号:T10340产 地:中国大陆
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T1034Docetaxel;多西他赛NSC 628503|||RP-56976;多西他赛|||NSC 628503|||RP-56976|||多烯紫杉醇
Docetaxel (RP-56976) is a semi-synthetic analog of paclitaxel, a microtubule depolymerization inhibitor (IC50=0.2 μM). Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression and exhibits apoptosis-inducing, anti-tumor activity.
价 格:¥电议型 号:T1034产 地:中国大陆
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T10339Antitrypanosomal agent 1;1-(3,4-二氯苯基)-3-(二甲基氨基)丙-1-酮盐酸盐Antitrypanosomal agent 1
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).
价 格:¥电议型 号:T10339产 地:中国大陆
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T10334Antifungal agent 2;化合物 T10334Antifungal agent 2
Antifungal agent 2 is a broad-spectrum fungal inhibitor that inhibits the growth of pertinent species of Cryptococcus, Candida, and Aspergillus at a concentration as low as 0.5 μg/mL.
价 格:¥电议型 号:T10334产 地:中国大陆
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T10324Anhydrosimvastatin;脱水辛伐他汀Dehydro simvastatin;Dehydro simvastatin|||脱水辛伐他汀
Anhydrosimvastatin (Dehydro simvastatin) is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.
价 格:¥电议型 号:T10324产 地:中国大陆
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T10319LAnamorelin Fumarate;富马酸阿拉莫林ONO-7643 Fumarate|||RC1291 Fumarate;ONO-7643 Fumarate|||RC1291 Fumarate||
Anamorelin Fumarate is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).
价 格:¥电议型 号:T10319L产 地:中国大陆
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T10315AN-3485;化合物 T10315AN-3485
AN-3485 is a Toll-Like Receptor(TLR) inhibitor (IC50s: 18 to 580 nM).
价 格:¥电议型 号:T10315产 地:中国大陆
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T10314AM103;化合物AM103AM 103;AM 103
AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).
价 格:¥电议型 号:T10314产 地:中国大陆
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T10306Amoxicillin D4;化合物 T10306Amoxycillin D4;Amoxycillin D4
Amoxicillin D4 (Amoxycillin D4) is a deuterium-labeled Amoxicillin. Amoxicillin is an antibiotic with broad-spectrum antimicrobial activity.
价 格:¥电议型 号:T10306产 地:中国大陆
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T10304Aminochlorthenoxazin;化合物 T10304ICI 350;ICI 350
Aminochlorthenoxazin is an antipyretic and analgesic agent.
价 格:¥电议型 号:T10304产 地:中国大陆
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T10299AMG PERK 44;化合物 AMG PERK 44AMG PERK 44
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) that induces autophagy.AMG PERK 44 inhibits GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM) and can be used in the study of cancer.
价 格:¥电议型 号:T10299产 地:中国大陆
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T10298L2AMG-548 dihydrochloride (864249-60-5 free base);化合物 T10298L2AMG-548 dihydrochloride;AMG-548 dihydroc
AMG-548 dihydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective against p38γ/p38δ. It is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50: 3 nM).
价 格:¥电议型 号:T10298L2产 地:中国大陆
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T10298LAMG-548;化合物 T10298LAMG-548
AMG-548 is an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ and is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50=3 nM)[1]. AMG-548 inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε[2].
价 格:¥电议型 号:T10298L产 地:中国大陆
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T10298AMG-548 hydrochloride (864249-60-5 free base);化合物 T10298AMG-548 hydrochloride;AMG-548 hydrochloride
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective against p38γ/p38δ. It is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50: 3 nM).
价 格:¥电议型 号:T10298产 地:中国大陆
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T10297LAMG 487;化合物AMG 487AMG 487
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
价 格:¥电议型 号:T10297L产 地:中国大陆
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T10297AMG 487 (S-enantiomer);化合物 T10297AMG 487 (S-enantiomer)
AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.
价 格:¥电议型 号:T10297产 地:中国大陆
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T10294AM9405;化合物 T10294AM9405
AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist. AM9405 inhibits twitch contraction of the ileum and the colon with IC 50 s of 45.71 and 0.076 nM, respectively. AM9405 significantly slowed mouse intestinal motility in physiological conditions. Moreover, AM9405 reversed hypermotility and reduced pain in mouse models mimicking symptoms of functional GI disorders, such as stress-induced diarrhea and writhing test.
价 格:¥电议型 号:T10294产 地:中国大陆