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T10684LCarnostatine hydrochloride;化合物 T10684LSAN9812 hydrochloride;SAN9812 hydrochloride
Carnostatine hydrochloride (SAN9812 hydrochloride) is a potent, selective inhibitor of carnosinase 1 (CN1), exhibiting a K_i of 11 nM against human recombinant CN1. This compound shows promise for the treatment of diabetic nephropathy (DN) [1].
价 格:¥电议型 号:T10684L产 地:中国大陆
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T10684Carnostatine;化合物 T10684SAN9812;SAN9812
Carnostatine (SAN9812) is a potent and selective carnosinase 1 ( CN1 ) inhibitor with a K i of 11 nM for human recombinant CN1. Carnostatine may be used to increase renal carnosine concentration as a potential therapeutic modality for diabetic nephropathy (DN). [1].
价 格:¥电议型 号:T10684产 地:中国大陆
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T10683Carmoxirole hydrochloride;卡莫昔罗EMD 45609 hydrochloride;EMD 45609 hydrochloride|||卡莫昔罗
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.
价 格:¥电议型 号:T10683产 地:中国大陆
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T10674Potassium Channel Activator 1;钾离子通道激活剂1ZINC34634569;钾离子通道激活剂1|||ZINC34634569
Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood disorders ADHD, schizophrenia, and other psychotic states.
价 格:¥电议型 号:T10674产 地:中国大陆
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T10670Candesartan-d4;坎地沙坦 D4CV-11974 D4;坎地沙坦 D4|||CV-11974 D4
Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.
价 格:¥电议型 号:T10670产 地:中国大陆
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T1066LKetanserin tartrate酒石酸酮色林KJK 945 tartrate|||KJK-945 tartrate|||KJK945 tartrate
Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist with antihypertensive activity, inhibits serotonin-induced vasoconstriction and platelet activation, and can be used in the study of systemic sclerosis.
价 格:¥电议型 号:T1066L产 地:中国大陆
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T10669Canagliflozin-d4;化合物 T10669Canagliflozin D4;Canagliflozin D4
Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.
价 格:¥电议型 号:T10669产 地:中国大陆
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T10667Calmidazolium chloride;钙调蛋白抑制剂R 24571;R 24571|||钙调蛋白抑制剂
Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist (Kd = 3 nM), antagonizing CaM-dependent phosphodiesterase(IC50 = 0.15 μM) and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase(IC50 = 0.35 μM). Calmidazolium chloride also induces apoptosis in certain cancer cell lines.
价 格:¥电议型 号:T10667产 地:中国大陆
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T10664Calcium 2-oxoglutarate;化合物 T10664Calcium 2-oxoglutarate
Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
价 格:¥电议型 号:T10664产 地:中国大陆
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T1066Ketanserin;酮色林R41468|||Ketanserin tartrate|||Ketanserinum;R41468|||凯他色林|||Ketanserin tartrate|||酮色林|
Ketanserin (Ketanserinum) is a quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist with potential antihypertensive and antiplatelet activities. Following administration, ketanserin binds to and inhibits the signaling mediated by 5-HTR2, which inhibits serotonin-dependent vasoconstriction and platelet activation.
价 格:¥电议型 号:T1066产 地:中国大陆
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T10656trans-C75;反-4-羧基-5-辛基-3-甲基-丁内酯(±)-C75;(±)-C75|||反-4-羧基-5-辛基-3-甲基-丁内酯
trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).
价 格:¥电议型 号:T10656产 地:中国大陆
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T10655c-Met inhibitor 1化合物c-Met inhibitor 13-[(2-甲基-2H-吲唑-5-基)硫基]-6-(1-甲基-1H-吡唑-4-基)-1,2,4-三唑并[4,3-B]哒嗪
c-Met inhibitor 1 is a c-Met receptor signaling pathway inhibitor, used for the treatment of cancer including glioblastoma, gastric, and pancreatic cancer.
价 格:¥电议型 号:T10655产 地:中国大陆
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T10654c-Met-IN-2;化合物 T10654c-Met-IN-2
c-Met-IN-2 is a selective and orally available c-Met inhibitor (IC50: 0.6 nM) with antitumor activity.
价 格:¥电议型 号:T10654产 地:中国大陆
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T10652Vimseltinib;化合物DCC-3014DCC-3014;DCC-3014
Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).
价 格:¥电议型 号:T10652产 地:中国大陆
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T10649c-Fms-IN-3;化合物c-Fms-IN-3c-Fms-IN-3
c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.
价 格:¥电议型 号:T10649产 地:中国大陆
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T10648c-Fms-IN-9;化合物 T10648c-Fms-IN-9
c-Fms-IN-9 is a c-FMS inhibitor. It inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT (IC50s: <0.01 μM and 0.1-1 μM).
价 格:¥电议型 号:T10648产 地:中国大陆
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T10647c-Fms-IN-8;化合物 T10647c-Fms-IN-8
c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.
价 格:¥电议型 号:T10647产 地:中国大陆
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T10646c-Fms-IN-7;化合物 T10646c-Fms-IN-7
c-Fms-IN-7 is a cFMS inhibitor (IC50: 18.5 nM).
价 格:¥电议型 号:T10646产 地:中国大陆
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T10645c-Fms-IN-6;化合物 T10645c-Fms-IN-6
c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: > 1 μM).
价 格:¥电议型 号:T10645产 地:中国大陆
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T10644c-Fms-IN-10;化合物 T10644c-Fms-IN-10
c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, a kinase inhibitor of FMS (Colony-stimulating factor-1 receptor, CSF-1R; IC50: 2 nM) with anti-tumor activity.
价 格:¥电议型 号:T10644产 地:中国大陆