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T17731LCL2A-SN-38 DCA 1279680-68-0(free base)
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make a
价 格:¥电议型 号:T17731L产 地:中国大陆
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T17257LWR-99210WR99210 hydrochloride(47326-86-3 free base);6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propox
WR-99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
价 格:¥电议型 号:T17257L产 地:中国大陆
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T17219Vatalanib free base
Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).
价 格:¥电议型 号:T17219产 地:中国大陆
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T16879LSHU 9119 acetateSHU 9119 acetate (168482-23-3 free base)
SHU 9119 acetate is a well-known antagonist of human melanocortin 3 and 4 (hMC3R, hMC4R) receptors and a partial hMC5R agonist. The IC50 values of human MC3R, MC4R and MC5R is 0.23, 0.06, and 0.09 nM respectively.
价 格:¥电议型 号:T16879L产 地:中国大陆
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T16790LRotigaptide TFA(355151-12-1 free base)Rotigaptide TFA
Rotigaptide TFA is a novel and specific modulator of Cx43 and is a potent AAP. Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress.
价 格:¥电议型 号:T16790L产 地:中国大陆
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T16083MizagliflozinGSK-1614235 free base;DSP-3235 free base;KGA-3235 free base
Mizagliflozin is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that can modify postprandial blood glucose excursion. Mizagliflozi
价 格:¥电议型 号:T16083产 地:中国大陆
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T15805LLY2510924 acetate(1088715-84-7 free base)
Ly2510924 acetate is an potent and selective CXCR4 antagonist. It prevents the binding of SDF-1 to CXCR4 with an IC50 of 0.079 nM.
价 格:¥电议型 号:T15805L产 地:中国大陆
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T15595LIRL-1620 acetateIRL-1620 acetate(142569-99-1 free base)
IRL-1620 acetate is an effective and selective agonist of Endothelin B receptor (ETB) with a Ki of 16 pM which is more selective than ETA with a Ki of 19 μM.
价 格:¥电议型 号:T15595L产 地:中国大陆
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T15369Lgamma-DGG acetate(6729-55-1 free base)γ-D-Glutamylglycine;γDGG
gamma-DGG acetate is a competitive blocker of AMPA receptor.
价 格:¥电议型 号:T15369L产 地:中国大陆
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T15259Evatanepag2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸;CP-533536 free acid
Evatanepag is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered locally as a single dose in rat models of fracture healing
价 格:¥电议型 号:T15259产 地:中国大陆
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T14665LMotixafortide TFA(664334-36-5,Free)TF 14016 TFA;BKT140 TFA;T140 TFA;BL-8040 TFA
Motixafortide is an antagonist of CXCR4 with IC50 of ~1 nM. It induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.
价 格:¥电议型 号:T14665L产 地:中国大陆
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T14378LAZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis.
价 格:¥电议型 号:T14378L产 地:中国大陆
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T13564LAZ7550 hydrochlorideAZ7550 hydrochloride (1421373-99-0 free base)
AZ7550 hydrochloride, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
价 格:¥电议型 号:T13564L产 地:中国大陆
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T13330WAY-213613 hydrochlorideWAY-213613 hydrochloride (868359-05-1 free base)
WAY-213613 hydrochloride is a selective nonsubstrate reuptake GLT-1/EAAT2 inhibitor (IC50: 85 nM, EAAT2). WAY-213613 hydrochloride displays 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3.8 μM, respectively). WAY-213613 hydrochloride s
价 格:¥电议型 号:T13330产 地:中国大陆
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T13214LTRPV4 agonist-1 free baseOUN67600
TRPV4 agonist-1 free base is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).
价 格:¥电议型 号:T13214L产 地:中国大陆
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T13112L1Tat-NR2B9c acetateNA-1 acetate;Tat-NR2B9c acetate (500992-11-0 Free base)
Tat-NR2B9c acetate is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c acetate disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B bin
价 格:¥电议型 号:T13112L1产 地:中国大陆
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T12942LSN50 acetate (213546-53-3 free base)
SN50 acetate is a cell permeable inhibitor of NF-κB translocation.
价 格:¥电议型 号:T12942L产 地:中国大陆
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T12896LShepherdin 79-87 acetateShepherdin 79-87 acetate (861224-28-4 free base)
Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.
价 格:¥电议型 号:T12896L产 地:中国大陆
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T12882LSetmelanotide Acetate(920014-72-8 free base)BIM-22493 Acetate;RM-493 Acetate;IRC-022493 Acetate
Setmelanotide Acetate is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
价 格:¥电议型 号:T12882L产 地:中国大陆
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T12506L1PMX 205 acetate(514814-49-4 free base)
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
价 格:¥电议型 号:T12506L1产 地:中国大陆