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T10382AS2863619 free baseAS2863619 free base
AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells. It is a potent, orally active CDK8 and CDK19 inhibitor (IC50s: 0.61 nM and 4.28 nM). STAT5 activation enhanced by AS2863619 free
价 格:¥电议型 号:T10382产 地:美洲
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T11087DOV-216,303 Free BaseDOV-216,303 Free Base
Dov-216,303 (free base) is an effective trihydroxytryptamine, norepinephrine and dopamine reuptake inhibitor with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively.It has similar antidepressant effects and increases monoamine re
价 格:¥电议型 号:T11087产 地:美洲
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T11128DutogliptinDutogliptin,PHX-1149 free base,
Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
价 格:¥电议型 号:T11128产 地:美洲
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T11432Glyoxalase I inhibitor free baseGlyoxalase I inhibitor free base
Glyoxalase I inhibitor (free base) , candidate for anticancer agents.?Glyoxalase I inhibitor (free base) is a potent Glyoxalase I (GLO1) inhibitor.
价 格:¥电议型 号:T11432产 地:美洲
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T11492GSK2983559 free acidGSK2983559 free acid
GSK2983559 free acid has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.?GSK2983559 free acid ?is a potent, specific and oral bioavailable receptor interacting protein
价 格:¥电议型 号:T11492产 地:美洲
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T11688ITI214 free baseITI214 free base
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM).
价 格:¥电议型 号:T11688产 地:美洲
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T12173DianemycinDianemycin,Nanchangmycin free acid,
Dianemycin is a polyether antibiotic produced by Streptomyces nanchangensis NS3226, and inhibits gram-positive bacteria.
价 格:¥电议型 号:T12173产 地:美洲
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T12945SNT-207858 free baseSNT-207858 free base
SNT-207858 free base is a selective, blood brain barrier penetrating, potent and orally active antagonist of melanocortin-4 (MC-4) receptor(IC50 of 22 nM (binding) and 11 nM (function), on the MC-4 receptor).
价 格:¥电议型 号:T12945产 地:美洲
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T13365YHO-13351 free baseYHO-13351 free base
YHO-13351 (free base) is the water-soluble prodrug of YHO-13177, and is a potent and specific BCRP inhibitor.
价 格:¥电议型 号:T13365产 地:美洲
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T13379(Z)-Leukadherin-1(Z)-Leukadherin-1,ADH-503 free base,
(Z)-Leukadherin-1 is an orally active and allosteric agonist of CD11b.
价 格:¥电议型 号:T13379产 地:美洲
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T13387ZatebradineZatebradine,UL-FS-49 free base,UL-FS-49CL free base
Zatebradine is a potent hyperpolarization-activated cyclic nucleotide-gated (HCN) channels inhibitor(IC50 of 1.96 ?M).
价 格:¥电议型 号:T13387产 地:美洲
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T15259EvatanepagEvatanepag,CP-533536 free acid,
Evatanepag is an agonist of EP2 receptor-selective prostaglandin E2 (PGE2). Which induces local bone formation (EC50: 0.3 nM).
价 格:¥电议型 号:T15259产 地:美洲
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T15431NemiralisibNemiralisib,GSK2269557 (free base),
Nemiralisib is a potent and highly selective inhibitor of PI3Kδ (pKi: 9.9).
价 格:¥电议型 号:T15431产 地:美洲
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T15561ImanixilImanixil,HOE-402(free base),
Imanixil is an inducer of the LDL receptor (LDLR) and it is also a potent cholesterol-lowering compound. It also inhibits very low density-lipoprotein (VLDL) production and consequently decreases atherosclerosis development.
价 格:¥电议型 号:T15561产 地:美洲
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T21312Afatinib free baseAfatinib free base,BIBW 2992,
Afatinib is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively).
价 格:¥电议型 号:T21312产 地:美洲
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T2378RGB-286638 free baseRGB-286638 free base
RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6.
价 格:¥电议型 号:T2378产 地:美洲
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T2467R406 free baseR406 free base,R406 (free base),
R406 (free base) is a potent Syk inhibitor.
价 格:¥电议型 号:T2467产 地:美洲
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T4602Hydrocortisone 21-hemisuccinateHydrocortisone 21-hemisuccinate,Hydrocortisone 21-he,hydrocortisone 2
Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
价 格:¥电议型 号:T4602产 地:美洲
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T5677SAR125884 hydrochlorid (1116743-46-4(free base))SAR125884 hydrochlorid (1116743-46-4(free base))
SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile,(IC50=4.2 nM).
价 格:¥电议型 号:T5677产 地:美洲
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T5862EzatiostatEzatiostat,Ezatiostat TFA (free base),TER199(free base)
Ezatiostat is a liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activity.
价 格:¥电议型 号:T5862产 地:美洲