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T82842BODIPY FL EDA free base;化合物 BODIPY FL EDA free baseBODIPY FL EDA free base
ODIPY FL EDA free base, an amine-based green fluorescent probe, possesses an R-NH2 group able to undergo coupling with aldehydes or ketones, forming reversible Schiff base adducts. These intermediates can be subsequently converted into stable amine derivatives through reduction with agents like sodium borohydride or sodium cyanoborohydride. The compound is applicable in the detection of both modified and normal deoxynucleotides, as well as in illustrating DNA damage and genomic DNA methylation.
价 格:¥电议型 号:T82842产 地:中国大陆
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T82805Butaprost free acid;化合物 Butaprost free acidButaprost free acid
(R)-Butaprost (free acid) is a prostaglandin E2 (PGE2) analog exhibiting high EP2 receptor subtype selectivity, commonly used to delineate EP receptor expression in human and animal tissues and cells. In 1986, Gardiner induced significant confusion regarding its structure by incorrectly identifying the selective C-16 epimer as (R)-butaprost (refer to the British Journal of Pharmacology, page 46, as TR 4979, and notes). By removing the methyl ester and restoring the native carboxylic acid at C-1,
价 格:¥电议型 号:T82805产 地:中国大陆
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T82372Free radical scavenger 1;化合物 Free radical scavenger 1Free radical scavenger 1
Compound 8, a free radical scavenger, exhibits an IC50 value of 43.39 μg/ml in neutralizing the DPPH radical [1].
价 格:¥电议型 号:T82372产 地:中国大陆
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T82011JBSNF-000028 free base;化合物 JBSNF-000028 free baseJBSNF-000028 free base
JBSNF-000028 is an orally active inhibitor of nicotinamide N-methyltransferase (NNMT) demonstrating inhibitory concentration (IC50) values of 0.033 ?M for human NNMT (hNNMT), 0.19 ?M for monkey NNMT (mkNNMT), and 0.21 ?M for mouse NNMT (mNNMT). This compound may be utilized in the study of metabolic disorders [1].
价 格:¥电议型 号:T82011产 地:中国大陆
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T8182LGuan-fu base A hydrochloride(1394-48-5 free base);化合物Guan-fu base A hydrochlorideGuan-fu base A hydr
Guan-fu base A hydrochloride is an antiarrhythmic alkaloid was isolated from Aconitum coreanum. Guanfu base A is hydrochloride a CYP2D6 inhibitor of human, monkey, and dog isoforms.
价 格:¥电议型 号:T8182L产 地:中国大陆
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T81784MK-2206 free base;化合物 MK-2206 free baseMK-2206 free base
MK-2206 free base is an allosteric Akt inhibitor that is both potent and selective, administered orally, exhibiting IC50 values of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. It demonstrates sensitivity in various breast cancer cell lines, including those with PIK3CA mutations and those exhibiting PTEN loss, indicating its potential for anticancer activities [1] [2].
价 格:¥电议型 号:T81784产 地:中国大陆
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T81727Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr free acid;化合物 Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr free a
Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr (free acid) serves as a selective and potent antagonist of the VPAC2 receptor [1].
价 格:¥电议型 号:T81727产 地:中国大陆
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T81638NSC363998 free base;化合物 NSC363998 free baseNSC363998 free base
NSC363998 (free base), an orally active compound, suppresses rCGG90-induced neurotoxicity and is utilized in researching neurodegenerative disorders, including Fragile X associated tremor/ataxia syndrome (FXTAS) [1].
价 格:¥电议型 号:T81638产 地:中国大陆
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T81589LOVA-A2 Peptide acetate(149755-57-7 free base);化合物 OVA-A2 Peptide acetate(149755-57-7 free base)OVA
产品可用于生物细胞实验
价 格:¥电议型 号:T81589L产 地:中国大陆
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T81575PA22-2 free acid;化合物 PA22-2 free acidCys-Laminin A chain 2091-2108;Cys-Laminin A chain 2091-2108
PA22-2 (free acid) (Cys-Laminin A chain 2091-2108), a peptide, promotes neurite outgrowth and facilitates the formation of neuron-like processes. It is utilized in the culturing of human adenoid cystic carcinoma cells and the development of peptide-functionalized supported phospholipid bilayers [1] [2] [3].
价 格:¥电议型 号:T81575产 地:中国大陆
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T81572PACAP (1-38) free acid;化合物 PACAP (1-38) free acidPACAP (1-38) free acid
PACAP (1-38) free acid, an endogenous neuropeptide, potently modulates gastrointestinal and neuroendocrine functions. It enhances antral motility, increases somatostatin secretion, and stimulates the release of vasoactive intestinal polypeptide, gastrin releasing peptide, and substance P, while concurrently inhibiting gastrin secretion. Additionally, it augments N-methyl-D-aspartate receptor function and upregulates brain-derived neurotrophic factor expression via RACK1 [1] [2].
价 格:¥电议型 号:T81572产 地:中国大陆
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T81571PACAP (1-38) free acid TFA;化合物 PACAP (1-38) free acid TFAPACAP (1-38) free acid TFA
PACAP (1-38) free acid TFA, an endogenous neuropeptide, effectively enhances antral motility and somatostatin secretion, while concurrently suppressing gastrin secretion and promoting the release of vasoactive intestinal polypeptide, gastrin releasing peptide, and substance P. Additionally, it amplifies N-methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1 [1] [2].
价 格:¥电议型 号:T81571产 地:中国大陆
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T8147Solifenacin;索利那新YM905 free base;索利那新|||YM905 free base
Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0, respectively.
价 格:¥电议型 号:T8147产 地:中国大陆
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T806662-PCCA hydrochloride;2-PCCA盐酸盐2-PCCA hydrochloride(1609624-97-6 Free base);2-PCCA hydrochloride(1609
2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with an EC50 value of 116 nM.
价 格:¥电议型 号:T80666产 地:中国大陆
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T80639HJC0152 free base;化合物 HJC0152 free baseHJC0152 free base
HJC0152 (free base) is an orally active, potent STAT3 inhibitor that impedes cell cycle progression, induces apoptosis, and notably reduces MDA-MB-231 xenograft tumor growth in mice [1].
价 格:¥电议型 号:T80639产 地:中国大陆
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T798055-HT2 agonist-1 free base;化合物 5-HT2 agonist-1 free base5-HT2 agonist-1 free base
Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. It is utilized in research pertaining to depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders, and other central nervous system disorders. [1]
价 格:¥电议型 号:T79805产 地:中国大陆
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T798035-HT2C agonist-3 free base;化合物 5-HT2C agonist-3 free base5-HT2C agonist-3 free base
5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-induced hyperactivity [1].
价 格:¥电议型 号:T79803产 地:中国大陆
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T79500LKSK94 FA;KSK94 甲酸盐KSK94 FA(2566716-07-0 Free base);KSK94 FA(2566716-07-0 Free base)
KSK94 FA is a potent histamine H3 receptor antagonist that inhibits H3 receptors and is used in the study of neuropathic pain and obesity.
价 格:¥电议型 号:T79500L产 地:中国大陆
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T79304Semapimod;化合物 SemapimodCPSI-2364|||CNI-1493 free base;CPSI-2364|||CNI-1493 free base
Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6. It hinders TLR4 signaling with an IC50 of approximately 0.3 μM, impedes p38 MAPK, and reduces nitric oxide production in macrophages. This compound shows promise for treating various inflammatory and autoimmune disorders [1] [2] [3].
价 格:¥电议型 号:T79304产 地:中国大陆
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T7893Bepotastine;贝托斯汀Bepotastine free base;Bepotastine free base|||贝托斯汀
Bepotastine (Bepotastine free base) free base is a histamine 1 (H1) receptor antagonis.
价 格:¥电议型 号:T7893产 地:中国大陆