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T2378RGB-286638 free baseRGB-286638 free base
RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6.
价 格:¥电议型 号:T2378产 地:美洲
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T2597NorgestrelNorgestrel,WY-3707,SH-70850
Norgestrel is a synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit
价 格:¥电议型 号:T2597产 地:美洲
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T4547GrazoprevirGrazoprevir,MK-5172,
MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), 0.15 nM (gt2b), respectively.
价 格:¥电议型 号:T4547产 地:美洲
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T4577CariprazineCariprazine,RGH-188,
Cariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
价 格:¥电议型 号:T4577产 地:美洲
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T4748Glycolaldehyde dimerGlycolaldehyde dimer,1,4-Dioxane-2,5-diol,Hydroxyacetaldehyde dimer
Glycoaldehyde Dimer is derivative of glycolaldehyde, which is the precursor molecule of various significant compounds including amino acid glycine and in the formose reaction.
价 格:¥电议型 号:T4748产 地:美洲
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T5126GlecaprevirGlecaprevir,ABT-493,
Glecaprevir is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM).
价 格:¥电议型 号:T5126产 地:美洲
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T5128RGX-104 HClRGX-104 HCl,SB742881,
RGX-104 is a liver X receptor (LXR) agonist with potential immunomodulating and antineoplastic activities. It modulates innate immunity via transcriptional activation of the ApoE gene.
价 格:¥电议型 号:T5128产 地:美洲
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T5289N-Acetyl-L-arginine dihydrateN-Acetyl-L-arginine dihydrate,N-Ac-L-arg-OH,
N-alpha-Acetylarginine is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic) pediatric population.
价 格:¥电议型 号:T5289产 地:美洲
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T5326Sugammadex (sodium)Sugammadex (sodium),Org25969,Sugammadex sodium
Sugammadex, a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent.
价 格:¥电议型 号:T5326产 地:美洲
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T5385RadiprodilRadiprodil,RGH-896,
Radiprodil (RGH-896) is an orally active and selective NMDA NR2B receptors antagonist. It was a potential treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPNP).
价 格:¥电议型 号:T5385产 地:美洲
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T5412RO4987655RO4987655,CH4987655,RG7167
RO4987655 is an orally active and highly selective MEK inhibitor (IC50: 5.2 nM for MEK1/MEK2).
价 格:¥电议型 号:T5412产 地:美洲
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T5707GALANGIN-3-METHYLETHERGALANGIN-3-METHYLETHER,3-O-Methylgalangin,3-Methylgalangin
GALANGIN-3-METHYLETHER has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. GALANGIN-3-METHYLETHER has hypolipidemic activity, the action is due to the inhibition of pancreatic lipase.
价 格:¥电议型 号:T5707产 地:美洲
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T5747ISOBERGAPTENISOBERGAPTEN
ISOBERGAPTEN is a plant growth regulating substance, it is the principal constituents responsible for the antimycobacterial activity of the roots of Heracleum maximum; it may form an important class of natural defensive agents against fungi.
价 格:¥电议型 号:T5747产 地:美洲
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T5S0669BergamotineBergamotine,Bergaptin,5-Geranoxypsoralen
1. Bergamotine can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-Aydiabetic mice.
价 格:¥电议型 号:T5S0669产 地:美洲
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T5S1054WilforgineWilforgine
1. Wilforgine exhibits insecticidal activity of some degree.
价 格:¥电议型 号:T5S1054产 地:美洲
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T5S2178FargesinFargesin,(+/-)-Fargesin,
1. Fargesin as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats. 2. Fargesin improves dyslipidemia and hyperglycemia by activating Akt and AMPK in WAT.
价 格:¥电议型 号:T5S2178产 地:美洲
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T6025DanoprevirDanoprevir,R7227,RG7227
Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).
价 格:¥电议型 号:T6025产 地:美洲
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T6120PralatrexatePralatrexate,Folotyn,10-Propargyl-10-deazaaminopterin
Pralatrexate is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.
价 格:¥电议型 号:T6120产 地:美洲
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T6242Rupatadine FumarateRupatadine Fumarate,Rupafin,Alergoliber
Rupatadine Fumarate (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.
价 格:¥电议型 号:T6242产 地:美洲
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T6254IdasanutlinIdasanutlin,RG7388,Ro 5503781
Idasanutlin (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).
价 格:¥电议型 号:T6254产 地:美洲