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T83720Biotin-Crosstide TFA；化合物 Biotin-Crosstide TFABiotin-Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly-OH；B
Biotin-crosstide is a derivative of the peptide Akt substrate crosstide, featuring biotinylation.
价 格：￥电议型 号：T83720产 地：中国大陆
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T83716KSL-128114 TFA；化合物 KSL-128114 TFAAc-rRrGrKkRrSHWX1X2DI-OH (X1=tert-Leucine; X2=Cyclohexylglycine)；Ac
KSL-128114, a peptide inhibitor of the membrane regulator syntenin (Ki = 300 nM), notably diminishes the viability of A2058 melanoma and patient-derived glioblastoma multiforme (GBM) cells in a concentration-dependent manner. Furthermore, when administered at 50 ?M, KSL-128114 elevates survival times in a patient-derived xenograft (PDX) mouse model of GBM, where mice were implanted intracranially with patient-derived GBM cells pre-cultured with KSL-128114.
价 格：￥电议型 号：T83716产 地：中国大陆
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T83709LIH383 TFA；化合物 LIH383 TFAPhe-Gly-Gly-Phe-Met-Arg-Arg-Lys-NH2；Phe-Gly-Gly-Phe-Met-Arg-Arg-Lys-NH2
LIH383 is a peptide agonist specifically designed to activate the chemokine (C-X-C motif) receptor 7 (CXCR7), which functions both as a chemokine and an opioid peptide scavenger receptor. Demonstrating a high selectivity, LIH383 activates CXCR7 with an effective concentration (EC50) of 0.61 nM, showing significantly lower affinity towards μ-, δ-, and κ-opioid receptors, as well as the nociceptin opioid peptide (NOP) receptor, even at concentrations of 3 ?M in β-arrestin recruitment assays. Furth
价 格：￥电议型 号：T83709产 地：中国大陆
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T83708Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA；化合物 Mca-KPLGL-Dap(Dnp)-AR-NH2 TFAMca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-N
Mca-KPLGL-Dap(Dnp)-AR-NH2 serves as a fluorogenic substrate specifically designed for matrix metalloproteinases (MMPs). This compound facilitates the quantification of MMP activity by releasing 7-methoxycoumarin-4-acetyl (Mca) upon enzymatic cleavage by MMPs, which exhibits fluorescence with excitation and emission maxima at 328 nm and 420 nm, respectively.
价 格：￥电议型 号：T83708产 地：中国大陆
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T83691EGFR Peptide (human, mouse) TFA；化合物 EGFR Peptide (human, mouse) TFAArg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-O
EGFR peptide, a PKC peptide substrate, mirrors an amino acid sequence from EGFR´s intracellular region and serves to gauge PKC activity in primary bovine retinal endothelial cells. At a concentration of 50 ?M, unlike its myristoylated counterpart, EGFR peptide does not inhibit PKC activity.
价 格：￥电议型 号：T83691产 地：中国大陆
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T83690[Leu144, Arg147]-PLP (139-151) TFA；化合物 [Leu144, Arg147]-PLP (139-151) TFA[Leu144, Arg147] Proteolipi
[Leu144,Arg147]-PLP (139-151) is a mutated fragment of the myelin proteolipid protein (PLP), featuring substitutions of tryptophan to leucine and histidine to arginine at positions 144 and 147, respectively. Immunizing mice with this peptide (50 ?g) mixed in complete Freund’s adjuvant (CFA) elevates IL-4 levels in the spleen. While it suppresses Th1 cell activation in vitro, it does not do so in vivo; instead, it promotes the development of regulatory T cells. Preimmunization with [Leu144, Arg14
价 格：￥电议型 号：T83690产 地：中国大陆
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T83688R 715 TFA；化合物 R 715 TFA[Ac-Lys-[D-βNal7,Ile8]des-Arg9]-BK|||Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D2Nal-Ile
R 715, a bradykinin B1 receptor antagonist, inhibits contractions in isolated human umbilical cords that express bradykinin B1 receptors (pA2 = 8.49). When administered at doses of 200, 400, and 600 ?g/kg, R 715 enhances latency to tail withdrawal in the tail-flick test for diabetic neuropathy mouse models induced by streptozotocin (STZ), signaling potential analgesic properties. Furthermore, at a 1 mg/kg per day dosage, it mitigates symptoms in a mouse model of experimental autoimmune encephalo
价 格：￥电议型 号：T83688产 地：中国大陆
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T83687Mca-RPPGFSAFK(Dnp)-OH TFA；化合物 Mca-RPPGFSAFK(Dnp)-OH TFA(7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gl
Mca-RPPGFSAFK(Dnp)-OH, a fluorogenic substrate specifically designed for endothelin-converting enzyme-1 (ECE-1), enables the quantification of ECE-1 activity through its distinctive fluorescence signal. When ECE-1 cleaves this substrate, it releases 7-methoxycoumarin-4-acetyl (Mca), which exhibits excitation and emission maxima at 328 nm and 420 nm, respectively, allowing for the direct measurement of enzyme activity.
价 格：￥电议型 号：T83687产 地：中国大陆
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T83669PMX-53 TFA；化合物 PMX-53 TFAAcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg]|||AcF-[OPdChaWR]|||3D53；AcPhe-[
PMX-53, a macrocyclic complement 5a (C5a) peptidomimetic and C5a receptor antagonist (IC50 = 0.3 ?M), effectively inhibits the C5a-induced secretion of myeloperoxidase (MPO) in isolated human polymorphonuclear leukocytes (PMNs). Administered orally at 10 mg/kg, PMX-53 mitigates vascular leakage, PMN infiltration, and the production of TNF-α and IL-6 in a rat peritoneal Arthus reaction model. Additionally, in a 3-nitropropionic acid (3-NP)-induced Huntington’s disease rat model, it alleviates bod
价 格：￥电议型 号：T83669产 地：中国大陆
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T83666Kisspeptin-10 (zebrafish) TFA；化合物 Kisspeptin-10 (zebrafish) TFATyr-Asn-Leu-Asn-Ser-Phe-Gly-Leu-Arg-T
Kisspeptin-10, a neuropeptide present in the brains, ovaries, and testes of zebrafish, plays a critical role in gonadal development and steroid expression. At a concentration of 10 ng/ml, it enhances the mRNA levels for the luteinizing hormone (Lh) receptor and both progestin receptor a (Pra) and Prb in zebrafish ovarian follicles. In female goldfish, doses of 0.1 and 1 ?g/g of Kisspeptin-10 elevate serum levels of luteinizing hormone, with no similar effect observed in male goldfish.
价 格：￥电议型 号：T83666产 地：中国大陆
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T83611(-)-15-Deoxyspergualin trihydrochloride；化合物 (-)-15-Deoxyspergualin trihydrochloride(-)-15-Deoxysperg
(-)-15-Deoxyspergualin trihydrochloride exhibits potent antitumor properties and demonstrates significant inhibition activity against mouse leukemia L-1210 [1].
价 格：￥电议型 号：T83611产 地：中国大陆
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T83548(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate；化合物 (D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance
(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate), an antagonist for Substance P and Bombesin, modulates ocular inflammatory responses triggered by antidromic trigeminal nerve stimulation [1].
价 格：￥电议型 号：T83548产 地：中国大陆
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T83527(Rac)-Neurodegenerative Disorder-Targeting Compound 1；化合物 (Rac)-Neurodegenerative Disorder-Targeting
(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.
价 格：￥电议型 号：T83527产 地：中国大陆
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T83520(S)-Campesterol；化合物 (S)-Campesterol5-Ergosten-3β-ol；5-Ergosten-3β-ol
´S-Campesterol (5-Ergosten-3β-ol) is a plant-derived sterol, commonly known as a phytosterol [1].´
价 格：￥电议型 号：T83520产 地：中国大陆
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T83512[1,6-Aminosuberic acid]-arginine-Vasotocin；化合物 [1,6-Aminosuberic acid]-arginine-Vasotocin[1,6-Aminos
[1,6-Aminosuberic acid]-arginine-Vasotocin, a synthetic peptide analogous to neurohypophyseal hormones, exerts an excitatory effect on the periodically oscillating neuron (PON) of A. fulica [1].
价 格：￥电议型 号：T83512产 地：中国大陆
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T83510[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2；化合物 [Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2BM-PACAP；BM
[Arg-15,-20,-21, Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic analogue of PACAP 1-27 that exhibits a relaxant effect [1].
价 格：￥电议型 号：T83510产 地：中国大陆
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T83509[Arg6]-β-Amyloid (1-40), england mutation；化合物 [Arg6]-β-Amyloid (1-40), england mutation[Arg6]-β-Amyl
β-Amyloid (1-40), England mutation, is a biologically active peptide with a histidine (His) to arginine (Arg) substitution at position 6, known to enhance oligomerization kinetics that serve as fibril seeds and increase neurotoxicity in cultured neurons. This alteration is one of several mutations in the beta-amyloid precursor gene implicated in autosomal dominant Alzheimer´s Disease across multiple kindreds.
价 格：￥电议型 号：T83509产 地：中国大陆
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T83508[Arg6]-β-Amyloid (1-42), england mutation；化合物 [Arg6]-β-Amyloid (1-42), england mutation[Arg6]-β-Amyl
[Arg6]-β-Amyloid (1-42), England mutation, is a biologically active peptide associated with autosomal dominant Alzheimer´s Disease in various kindreds. The English (H6R) mutation disrupts H6 interactions due to several mutations in the beta-amyloid precursor gene.
价 格：￥电议型 号：T83508产 地：中国大陆
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T83503[D-Arg2]Dermorphin-(1-4) amide；化合物 [D-Arg2]Dermorphin-(1-4) amide[D-Arg2]Dermorphin-(1-4) amide
[D-Arg2]Dermorphin-(1-4) amide is an N-terminal truncated peptide of [D-Arg2]dermorphin noted for its hypothermic and analgesic effects. This compound also demonstrates degradation when subjected to soluble mouse liver and brain extracts [1].
价 格：￥电议型 号：T83503产 地：中国大陆
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T83502[Deamino-4-valine, 8-D-arginine]-Vasopressin；化合物 [Deamino-4-valine, 8-D-arginine]-VasopressindVDAVP；
[Deamino-4-valine, 8-D-arginine]-Vasopressin (dVDAVP) is a highly potent and specific antidiuretic agent, exhibiting prolonged effects [1] [2].
价 格：￥电议型 号：T83502产 地：中国大陆
