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  • T14629Bis-PEG10-acid;化合物 T14629Bis-PEG10-acid

    Bis-PEG10-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T14629产 地:中国大陆

  • T14529LBentiromide acetate;苯替酪胺醋酸盐Bentiromide acetate(37106-97-1 Free base);Bentiromide acetate(37106-97-1

    Bentiromide acetate is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. It is broken down by the pancreatic enzyme chymotrypsin, yielding p-aminobenzoic acid (PABA).

    价 格:¥电议型 号:T14529L产 地:中国大陆

  • T14529Bentiromide;胰功定Bentiromide

    Bentiromide is a peptide used in the bentiromide test to monitor the adequacy of supplemental pancreatic therapy and to screen exocrine pancreatic insufficiency.

    价 格:¥电议型 号:T14529产 地:中国大陆

  • T14528Benoxafos;化合物 T14528HOE 2910;HOE 2910

    Benoxafos, HOE 2910, is an insecticide.

    价 格:¥电议型 号:T14528产 地:中国大陆

  • T14502BAY-299;化合物BAY-299BAY299|||BAY 299;BAY299|||BAY 299

    BAY-299 is an effecitve inhibitor of the bromodomain and PHD finger family member BRPF2 and the TATA box binding protein-associated factors TAF1 and TAF1L with IC50s of 67 nM, 8 nM, and 106 nM, respectively.

    价 格:¥电议型 号:T14502产 地:中国大陆

  • T14429Azido-PEG3-maleimide;化合物 T14429Azido-PEG3-maleimide

    Azido-PEG3-maleimide is a PEG-based PROTAC linker primarily used for the synthesis of PROTACs[1]. Additionally, it serves as a cleavable 3-unit PEG ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[2].

    价 格:¥电议型 号:T14429产 地:中国大陆

  • T14383AZD8329;化合物 T14383AZD8329

    AZD8329 is a selectable and potent inhibitor of human recombinant 11β-HSD1 and isolated human adipocyte 11?-HSD1 and is an inhibitor of rat 11β-HSD1 (IC50 - 89nM) and dog recombinant 11β-HSD1. AZD8329 has a higher affinity for 11β-HSD1 than human recombinant 11β-HSD2 and 17 AZD8329 has the ability to reduce the activity of 11β-HSD1 in adipose tissue and liver samples.

    价 格:¥电议型 号:T14383产 地:中国大陆

  • T14374AZD2906;化合物 T14374AZD2906

    AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow.

    价 格:¥电议型 号:T14374产 地:中国大陆

  • T14357Spebrutinib besylate;化合物 T14357CC-292 (besylate)|||AVL-292 (benzenesulfonate);CC-292 (besylate)|||AV

    Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s).

    价 格:¥电议型 号:T14357产 地:中国大陆

  • T14343Atreleuton;化合物 T14343ABT-761|||VIA-2291;ABT-761|||VIA-2291

    Atreleuton (ABT-761) is a potent and selective inhibitor of leukotriene formation[1][2][3]. As a reversible and orally bioavailable 5-Lipoxygenase (5-LO) inhibitor, Atreleuton (ABT-761) exhibits selectivity.

    价 格:¥电议型 号:T14343产 地:中国大陆

  • T1433Ritodrine hydrochloride;盐酸利托君DU21220|||Ritodrine HCl|||NSC 291565;DU21220|||盐酸利托君|||Ritodrine HCl|||

    Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vasc

    价 格:¥电议型 号:T1433产 地:中国大陆

  • T14329Ascamycin;化合物AscamycinAscamycin

    Ascamycin is a 5´-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and inhibits Xanthomonas citri, Xanthomonas oryzae and phage with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL respectively.

    价 格:¥电议型 号:T14329产 地:中国大陆

  • T14299AP20187;化合物AP20187B/B Homodimerizer;B/B Homodimerizer

    AP20187 (B/B Homodimerizer) is a cell-permeable compound employed to dimerize FK506-binding protein (FKBP) fusion proteins, thereby initiating biological signaling cascades, gene expression, or disrupting protein-protein interactions.

    价 格:¥电议型 号:T14299产 地:中国大陆

  • T14298Rimiducid;AP1903Rimiducid

    Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affinity. Rimiducid is a dimerizer agent that acts by cross-linking the FKBP domains. It dimerizes the Caspase 9 suicide switch and rapidly induces apoptosis.

    价 格:¥电议型 号:T14298产 地:中国大陆

  • T14297AP1867;化合物 T14297AP1867

    AP1867 is a synthetic FKBP12F36V-directed ligand.

    价 格:¥电议型 号:T14297产 地:中国大陆

  • T14296Antitumor agent-3;化合物 T14296Antitumor agent-3

    Antitumor agent-3 is a potent compound. It comprises a new imidazopyridine having excellent antitumor activity as an active ingredient.

    价 格:¥电议型 号:T14296产 地:中国大陆

  • T14295Antipain;化合物 T14295Antipain

    Antipain is a protease inhibitor isolated from Actinomycetes. Antipain inhibits N-methyl-N´-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations[1][2].

    价 格:¥电议型 号:T14295产 地:中国大陆

  • T14293Annonacin;化合物 T14293Annonacin

    Annonacin is an Acetogenin and promotes cytotoxicity via a pathway inhibiting the mitochondrial complex and it is the active agent found in Graviola leaf extract to act as an inhibitor of sodium/potassium (NKA) and sarcoplasmic reticulum (SERCA) ATPase pumps[1].

    价 格:¥电议型 号:T14293产 地:中国大陆

  • T14292Anitrazafen;阿尼扎芬LY 122512;阿尼扎芬|||LY 122512

    Anitrazafen is a locally effective anti-inflammatory agent that has been shown to have COX-2 inhibitor activity.

    价 格:¥电议型 号:T14292产 地:中国大陆

  • T14291Anisindione;茴茚二酮Anisindione

    Anisindione is a synthetic anticoagulant and an indanedione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K–mediated gamma-carboxylation of precursor proteins.

    价 格:¥电议型 号:T14291产 地:中国大陆

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