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T1615Irbesartan;厄贝沙坦SR-47436|||BMS-186295;厄贝沙坦|||SR-47436|||BMS-186295
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
价 格:¥电议型 号:T1615产 地:中国大陆
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T16129MPI_5a;化合物MPI_5aMPI_5a
MPI_5a is an effective and selective inhibitor of HDAC6 (IC50=36 nM). MPI_5a weakly inhibits other HDAC isoforms and it also inhibits acyl-tubulin accumulation in cells (IC50: 210 nM).
价 格:¥电议型 号:T16129产 地:中国大陆
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T16101ML-290;化合物ML-290ML-290
ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.
价 格:¥电议型 号:T16101产 地:中国大陆
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T16085MK-0429化合物 T16085L-000845704
MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).
价 格:¥电议型 号:T16085产 地:中国大陆
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T16029Mcl1-IN-3;化合物 T16029Mcl1-IN-3
Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.
价 格:¥电议型 号:T16029产 地:中国大陆
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T15946MA-2029;化合物 T15946MA-2029
MA-2029 is selective for the motilin receptor over various other receptors and ion channels. MA-2029 is a selective and competitive motilin receptor antagonist (IC50=4.9 nM). MA-2029 may be useful for gastrointestinal disorders associated with disturbed gastrointestinal motility.
价 格:¥电议型 号:T15946产 地:中国大陆
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T15929m-PEG8-Br;化合物 T15929m-PEG8-Br
m-PEG8-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15929产 地:中国大陆
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T15829L 888607 Racemate;化合物 T15829L 888607 Racemate|||L 888607 Racemate;L 888607 Racemate|||L 888607 Racem
L 888607 Racemate is a selective antagonist of prostaglandin D2 receptor subtype 1 (DP1) (Kis: 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively).
价 格:¥电议型 号:T15829产 地:中国大陆
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T15815LY3295668;化合物AK-01AK-01;AK-01
LY3295668 (AK-01) is a selective inhibitor of Aurora A with Kis of 0.8 nM and 1038 nM for Aurora A and B, respectively.
价 格:¥电议型 号:T15815产 地:中国大陆
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T15812LY2979165;化合物LY2979165mGlu2 agonist;mGlu2 agonist
LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.
价 格:¥电议型 号:T15812产 地:中国大陆
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T15811LY2955303;化合物LY2955303LY2955303
LY2955303 is an effective and selective antagonist of retinoic acid receptor gamma (RARγ, Ki = 1.09 nM).
价 格:¥电议型 号:T15811产 地:中国大陆
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T15810LY2922470;化合物LY2922470LY2922470
LY2922470 is a potent, selective G protein-coupled receptor 40 (GPR40) agonist, with EC50s of 7 nM for human GPR40, 1 nM for mouse GPR40 and 3 nM for rat GPR40, respectively. LY2922470 reduces glucose levels along and increases insulin and GLP-1 significantly.
价 格:¥电议型 号:T15810产 地:中国大陆
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T15799LY2940094;化合物LY-2940094LY-2940094;LY-2940094
LY2940094 (LY-2940094) decreases ethanol self-administration in animal models. LY2940094 is an effective, selective, and orally available nociceptin receptor antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM).
价 格:¥电议型 号:T15799产 地:中国大陆
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T15760LLintopride HCl;Lintopride 盐酸盐Lintopride HCl(107429-63-0 Free base);Lintopride HCl(107429-63-0 Free b
Lintopride HCl is a 5HT-4 antagonist.
价 格:¥电议型 号:T15760L产 地:中国大陆
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T15729LDN-91946;化合物LDN-91946LDN-91946
LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 μM).
价 格:¥电议型 号:T15729产 地:中国大陆
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T15629JTE-013;化合物JTE-013JTE-013
JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively).
价 格:¥电议型 号:T15629产 地:中国大陆
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T15615JND3229;化合物JND3229JND3229
JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma.
价 格:¥电议型 号:T15615产 地:中国大陆
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T15562Imazamox;甲氧咪草烟CL29926|||(±)-Imazamox;CL29926|||甲氧咪草烟|||(±)-Imazamox
Imazamox ((±)-Imazamox) is a systemic herbicide with high selectivity, high activity, safety and broadspectrum activity. Imazamox inhibits the production of acetolactate synthase (ALS) in plants, which would then inhibit plant growth and ultimately lead to plant death.
价 格:¥电议型 号:T15562产 地:中国大陆
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T15554IHVR-19029;化合物 T15554IHVR-19029
IHVR-19029 is an effective endoplasmic reticulum (ER) α-glucosidases I and II inhibitor (IC50: 0.48 μM for ER a-glucosidase I). IHVR-19029 efficiently blocks the replication of several hemorrhagic fever viruses, such as Ebola virus, Dengue virus, and Rift Valley fever virus.
价 格:¥电议型 号:T15554产 地:中国大陆
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T15529Hydroxy-PEG4-(CH2)2-Boc丙酸叔丁酯-四聚乙二醇丙酸叔丁酯-四聚乙二醇
Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc can also be used in the synthesis of PROTAC.
价 格:¥电议型 号:T15529产 地:中国大陆