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T15472Hepsulfam;化合物 T15472NCI 329680|||ZINC01574758;NCI 329680|||ZINC01574758
Hepsulfam is an anticancer agent. It also displays excellent antileukemic activity (a median IC50: 0.91 μg/mL in a panel of different tumors).
价 格:¥电议型 号:T15472产 地:中国大陆
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T15430GSK2256294A;化合物GSK2256294AGSK 2256294;GSK 2256294
GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.
价 格:¥电议型 号:T15430产 地:中国大陆
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T15429GSK2194069;化合物GSK2194069GSK2194069
GSK2194069 is an active β-keto reductase (KR)-specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released CoA.GSK2194069 inhibits the proliferation of FAS in cancer cells through the action of acetoacetyl-coenzyme A and NADPH.
价 格:¥电议型 号:T15429产 地:中国大陆
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T15425GSK1702934A;化合物 T15425GSK1702934A
GSK1702934A is a selective TRPC3 agonist. It modulates cardiac contractility and f arrhythmogenesis by activation of TRPC3.
价 格:¥电议型 号:T15425产 地:中国大陆
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T15408GNE 5729;化合物 T15408GNE 5729
GNE 5729 is an NMDAR of brain permeable positive allosteric modulator (EC50: 37 nM for GluN2A; 4.7 and 9.5 μM for GluN2C and GluN2D, respectively).
价 格:¥电议型 号:T15408产 地:中国大陆
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T15389LGlucagon (1-29), bovine, human, porcine hydrochloride;盐酸胰高血糖素Porcine glucagon hydrochloride|||Glucag
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylation. Glucagon (1-29), bovine, human, porcine hydrochloride(Porcine glucagon hydrochloride) stimulates gluconeogenesis.
价 格:¥电议型 号:T15389L产 地:中国大陆
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T15389Glucagon (1-29), bovine, human, porcine;胰高血糖素Porcine glucagon|||Glucagon;胰高血糖素|||Porcine glucagon|||
Glucagon is a peptide hormone, produced by pancreatic α-cells. Glucagon reduces the activity of HNF-4. Glucagon stimulates gluconeogenesis. Glucagon enhances HNF4α phosphorylation.
价 格:¥电议型 号:T15389产 地:中国大陆
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T1537Rapamycin;雷帕霉素Sirolimus|||AY 22989|||NSC-2260804;Sirolimus|||AY 22989|||雷帕霉素|||NSC-2260804
Rapamycin (AY 22989) is a natural product of macrolides, an mTOR inhibitor with specificity (HEK293 cells: IC50=0.1 nM). Rapamycin has immunosuppressive activity and induces autophagy.
价 格:¥电议型 号:T1537产 地:中国大陆
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T15369Lgamma-DGG acetate(6729-55-1 free base);化合物gamma-DGG acetateγDGG|||γ-D-Glutamylglycine;γDGG|||γ-D-Glu
gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.
价 格:¥电议型 号:T15369L产 地:中国大陆
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T15329Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB;化合物 T15329Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a cleavable three-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T15329产 地:中国大陆
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T1530Mitiglinide calcium hydrate;米格列奈钙KAD-1229 calcium hydrate|||Mitiglinide calcium|||S-21403 calcium hy
Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. Mitiglinide belongs to the meglitinide class of blood glucose-lowering drugs and is currently co-marketed in Japan by Kissei and Takeda.
价 格:¥电议型 号:T1530产 地:中国大陆
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T15299Fluorescein-thiourea-PEG6-acid;化合物 T15299Fluorescein-thiourea-PEG6-acid
Fluorescein-thiourea-PEG6-acid is a polyethylene glycol (PEG) derived linker commonly employed in the synthesis of proteolysis targeting chimeras (PROTACs) [1].
价 格:¥电议型 号:T15299产 地:中国大陆
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T15298Fluorescein-thiourea-PEG4-azide;化合物 T15298Fluorescein-thiourea-PEG4-azide
Fluorescein-thiourea-PEG4-azide, a PEG-based PROTAC linker, is employed for the synthesis of PROTACs.
价 格:¥电议型 号:T15298产 地:中国大陆
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T15297Fluorescein-thiourea-PEG2-azide;化合物 T15297Fluorescein-thiourea-PEG2-azide
Fluorescein-thiourea-PEG2-azide is a PEG-derived linker commonly applied for the synthesis of PROTACs[1].
价 格:¥电议型 号:T15297产 地:中国大陆
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T15296Fluorescein-PEG6-NHS ester;化合物 T15296Fluorescein-PEG6-NHS ester
Fluorescein-PEG6-NHS ester is a polyethylene glycol (PEG)-derived proteolysis targeting chimera (PROTAC) linker employed for PROTAC synthesis [1].
价 格:¥电议型 号:T15296产 地:中国大陆
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T15295Fluorescein-PEG6-bis-NHS ester;化合物 T15295Fluorescein-PEG6-bis-NHS ester
Fluorescein-PEG6-bis-NHS ester is a polyethylene glycol (PEG)-based linker used for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T15295产 地:中国大陆
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T15294Fluorescein-PEG5-acid;化合物 T15294Fluorescein-PEG5-acid
Fluorescein-PEG5-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15294产 地:中国大陆
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T15293Fluorescein-PEG4-acid;化合物 T15293Fluorescein-PEG4-acid
Fluorescein-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15293产 地:中国大陆
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T15292Fluorescein-PEG3-NH-Boc;化合物 T15292Fluorescein-PEG3-NH-Boc
Fluorescein-PEG3-NH-Boc is a polyethylene glycol (PEG)-based proteolysis-targeting chimera (PROTAC) linker utilized for the synthesis of PROTACs[1].
价 格:¥电议型 号:T15292产 地:中国大陆
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T15291Fluorescein-PEG3-amine;化合物 T15291Fluorescein-PEG3-amine
Fluorescein-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15291产 地:中国大陆