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T15572IN-1130IN1130,IN 1130
IN-1130 is a selective inhibitor of ALK5 with IC50 values of 5.3 nM, 36 nM, and 4.3 μM for phosphorylation of ALK5-mediated Smad3, ALK5 phosphorylation of casein and p38α mitogen-activated protein kinase.
价 格:¥电议型 号:T15572产 地:中国大陆
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TQ0211BrusatolNrf2,oxygen,CT-26,NSC172924,NSC-172924,defense,stress,Keap1-Nrf2,Brusatol,chemosensitization
Brusatol is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
价 格:¥电议型 号:TQ0211产 地:中国大陆
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T8482Ripretinibc-Kit,Inhibitor,DCC2618,Vascular endothelial growth factor receptor,CD135,CD117,Platelet-d
Ripretinib is an orally bioavailable inhibitor of KIT and PDGFRA.
价 格:¥电议型 号:T8482产 地:中国大陆
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T8311ObefazimodObefazimod,HIV,Inhibitor,Human immunodeficiency virus,inhibit,ABX 464
ABX-464 is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) (IC50 : 0.1 μM - 0.5 μM)
价 格:¥电议型 号:T8311产 地:中国大陆
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T7108OmberacetamInhibitor,Omberacetam,iGluR,Ionotropic glutamate receptors,SGS 111,GVS 111,SGS111,inhibit
Omberacetam is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other related racetam compounds.
价 格:¥电议型 号:T7108产 地:中国大陆
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T39113LPovorcitinib phosphateJAK,Povorcitinib,Povorcitinib phosphate,CLE,Janus kinase,JAK1 inhibitor,Inhibi
Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the treatment of cutaneous lupus erythematosus and Lichen planus.
价 格:¥电议型 号:T39113L产 地:中国大陆
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T11098Droloxifene
Droloxifene, a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells.Fluroxifene has anti-estrogen and anti-implantation effects.Fluroxifene prevented bone loss in ovariectomized rats.
价 格:¥电议型 号:T11098产 地:中国大陆
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TP1936L1RFRP3(human) acetate(311309-27-0 free base)RFRP-3(human) acetate(311309-27-0 free base),RFRP3(human)
RFRP-3(human) acetate, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) acetate is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM.
价 格:¥电议型 号:TP1936L1产 地:中国大陆
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T11031hDHODH-IN-7hDHODH IN 7,hDHODHIN7
hDHODH-IN-7 is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor. hDHODH-IN-7 and pMIC50 of 7.4 have antiviral effects.
价 格:¥电议型 号:T11031产 地:中国大陆
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T11342LG-5555p21 activated kinases,G-5555,PAK,Inhibitor,G 5555,inhibit,G5555
G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).
价 格:¥电议型 号:T11342L产 地:中国大陆
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T11063DMT1 blocker 1DMT-1 blocker 1,DMT1 blocker 1
DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.
价 格:¥电议型 号:T11063产 地:中国大陆
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T60065WAY-118959-AWAY 118959 A,WAY118959A
WAY-118959-A is a potential microtubule acetylation inhibitor.
价 格:¥电议型 号:T60065产 地:中国大陆
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T67455-IodotubercidinInhibitor,5-Iodotubercidin,NSC-113939,5Iodotubercidin,inhibit,5 Iodotubercidin,ADK,A
5-Iodotubercidin is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.
价 格:¥电议型 号:T6745产 地:中国大陆
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T9114β-CaryophylleneβCaryophyllene,Cannabinoid Receptor,β-Caryophyllene,β Caryophyllene,Endogenous Metabo
β-Caryophyllene acts as an CB2 receptor agonist.
价 格:¥电议型 号:T9114产 地:中国大陆
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T11129LDuvelisib (R enantiomer) hydrochloride
Duvelisib (R enantiomer) hydrochloride is a PI3K inhibitor. Duvelisib (R enantiomer) hydrochloride is the less active enantiomer of Duvelisib.
价 格:¥电议型 号:T11129L产 地:中国大陆
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TN1141Isodeoxyelephantopininhibit,Reactive Oxygen Species,Inhibitor,Isodeoxyelephantopin,NF-κB,Nuclear fac
Isodeoxyelephantopin can inhibit the growth of various tumor cells.
价 格:¥电议型 号:TN1141产 地:中国大陆
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T7428SBI-115G protein-coupled Bile Acid Receptor 1,GPCR19,TGR5,SBI115,GPBAR1,Inhibitor,SBI-115,SBI 115,G-
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
价 格:¥电议型 号:T7428产 地:中国大陆
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T9116SMCCSMCC,ADC Linkers,inhibit,Antibody-drug conjugates linkers,Inhibitor
N-Succinimidyl 4-(N-maleimidomethyl)cycl(SMCC), also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a heterobifunctional protein crosslinker.
价 格:¥电议型 号:T9116产 地:中国大陆
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T11237LCamizestrant TFA
Camizestrant TFA is a potent and orally active antagonist of estrogen receptor (ER).
价 格:¥电议型 号:T11237L产 地:中国大陆
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T7791IberdomideCELMoD,H929,CRBN,Ligands for E3 Ligase,KMS12PE,KMS11,orally,sub-G1,Apoptosis,Iberdomide,ce
Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
价 格:¥电议型 号:T7791产 地:中国大陆