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产品数:86101
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TN1100NepodinInhibitor,AMP-activated protein kinase,Musizin,Parasite,AMPK,Nepodin,inhibit
Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity. Nepodin has an antidiabetic effect, which is at least partly mediated by stimulation of GLUT4 translocation via AMPK activation by nepodin.
价 格:¥电议型 号:TN1100产 地:中国大陆
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T8111Triacontanoic AcidTriacontanoic Acid
Triacontanoic Acid belongs to the class of organic compounds known as very long-chain fatty acids.
价 格:¥电议型 号:T8111产 地:中国大陆
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T6S0117Avicularininhibit,inflammation,COX,Peroxisome proliferator-activated receptors,GLUT,oxidative stress
1. Avicularin exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. 2. Avicularin inhibits the accumulation of the intracellular lipids by decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase.
价 格:¥电议型 号:T6S0117产 地:中国大陆
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T11909LY2444296
LY2444296 is an orally active and selective antagonist of kappa opioid receptor(Ki = 1 nM).
价 格:¥电议型 号:T11909产 地:中国大陆
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T10782CGP52411
CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM). CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells and dramatically inhibits and reverses the formation of β-amyloid Aβ42 fibril aggregates. CGP52411 can be used in studies about Alzheimer´s diseases.
价 格:¥电议型 号:T10782产 地:中国大陆
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T8116Azulenenaphthalene,chamomile,scaffold,Azulene,oil,Cyclopentacycloheptene,distillation,inhibit,Human
Bicyclo[5.3.0]Decapentaene is a natural product.
价 格:¥电议型 号:T8116产 地:中国大陆
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T8440LASSBio-1135LASSBio 1135,LASSBio1135
LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.
价 格:¥电议型 号:T8440产 地:中国大陆
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TQ0032RosiptorAQX1125,Rosiptor,Phosphatase,AQX 1125,Inhibitor,inhibit
Rosiptor (AQX-1125) is an orally-active and specific phosphatase SHIP1 activator with anti-inflammatory effects.
价 格:¥电议型 号:TQ0032产 地:中国大陆
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T23549YM 511YM 511
YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM 511 slightly inhibits production of other steroid hormones. YM 511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones.
价 格:¥电议型 号:T23549产 地:中国大陆
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T8664SSD114 hydrochlorideSSD114,Gamma-aminobutyric acid Receptor,Inhibitor,SSD 114,SSD-114,SSD114 hydroch
SSD114 hydrochloride is a GABAB receptor positive allosteric modulator.
价 格:¥电议型 号:T8664产 地:中国大陆
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T11238LEtamicastat hydrochloride
Etamicastat hydrochloride is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.
价 格:¥电议型 号:T11238L产 地:中国大陆
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T9465ZZW-115 hydrochloridenecroptosis,cell,PDAC,growth,ZZW-115,pancreatic,ZZW115 hydrochloride,ZZW 115 hy
ZZW-115 hydrochloride inhibits the activity of NUPR1.
价 格:¥电议型 号:T9465产 地:中国大陆
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T6763XevinapantSM 406,SM406,Xevinapant,AT-406,oral,inhibit,Debio 1143,ovarian,IAP,degradation,Smac,AT 406
AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
价 格:¥电议型 号:T6763产 地:中国大陆
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T7011Verubecestatorally,Beta-secretase,β-Secretase,inhibit,Aβ40,BACE1,MK8931,Alzheimer’s,BACE,Inhibitor,M
Verubecestat (MK-8931) is an effective and specific β-secretase inhibitor and β-site APP-cleaving enzyme 1 inhibitor or BACE1 protein inhibitor.
价 格:¥电议型 号:T7011产 地:中国大陆
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TP1188LCortistatin 14, human, rat acetateCortistatin 14, human, rat acetate
Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects and remarkable anti-inflammatory properties. Cortistatin 14, human, rat acetate binds and exerts its fun
价 格:¥电议型 号:TP1188L产 地:中国大陆
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TQ0311GSK163090Dopamine Receptor,5-HT1A,GSK163090,Inhibitor,5-hydroxytryptamine Receptor,antidepressant,an
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
价 格:¥电议型 号:TQ0311产 地:中国大陆
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TP1106Lα-Factor Mating Pheromone, yeast acetateα Factor Mating Pheromone, yeast acetate,αFactor Mating Pher
α-Factor Mating Pheromone, yeast acetate is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells.
价 格:¥电议型 号:TP1106L产 地:中国大陆
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TP2110LTAT-Gap19 acetateTAT Gap19 acetate,TATGap19 acetate
TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis in mice. TAT-Gap19 acetate does not inhibit the corresponding Cx43 GJCs.
价 格:¥电议型 号:TP2110L产 地:中国大陆
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TN7214Galdosol6β,20Epoxy11,12dihydroxyabieta8,11,13triene7,20dione
Galdosol is a natural product found in Perovskia abrotanoides.
价 格:¥电议型 号:TN7214产 地:中国大陆
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T11321FR194738 free baseFR194738 free base,FR-194738 free base
FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.?
价 格:¥电议型 号:T11321产 地:中国大陆