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T6918OlmutinibOlmutinib,ErbB-1,inhibit,HER1,EGFR,Epidermal growth factor receptor,Inhibitor
Olmutinib is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form.
价 格:¥电议型 号:T6918产 地:中国大陆
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TN7086PropiosyringonePropiosyringone
Propiosyringone is from the degradation of Eucalyptus globulus wood by wood-rotting fungi.
价 格:¥电议型 号:TN7086产 地:中国大陆
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T8732CTPI-2macrophage,carrier,CTPI-2,NSCLC,transporter,glucose,steatohepatitis,CTPI 2,Mitochondrial Metab
CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet.
价 格:¥电议型 号:T8732产 地:中国大陆
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T6134IEM 1754 2HBrAMPA receptor,channel block,IEM 1754,Ionotropic glutamate receptors,voltage dependence,
IEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
价 格:¥电议型 号:T6134产 地:中国大陆
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T643194-benzyloxycarbonylamino-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester
4-benzyloxycarbonylamino-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester is a bioactive substances.
价 格:¥电议型 号:T64319产 地:中国大陆
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T67883N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-pip
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-piperidylmethyl)benzofuran-4-carboxamide is a specific inhibitor of histone modifier enhancer of zeste 2 (EZH2). EZH2 is aberrantly overexpressed in a number of human cancers that controls the adaptive response via regulation of Treg activity. Intratumoral EZH2 expression has also been shown to control the innate immunity
价 格:¥电议型 号:T67883产 地:中国大陆
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T9063N-[5-[(4-Bromophenyl)methylene]-4,5-dihydro-4-oxo-2-thiazolyl]-1-naphthalenesulfonamideInhibitor,ves
Pitstop 2 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research.
价 格:¥电议型 号:T9063产 地:中国大陆
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TP1367[D-Ala2]leucine-enkephalinOpioid Receptor,[DAla2]leucineenkephalin,Inhibitor,[D Ala2]leucine enkepha
[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.
价 格:¥电议型 号:TP1367产 地:中国大陆
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T6600Naftopidil dihydrochlorideprostate,Naftopidil,hyperplasia,pressure,inhibit,Naftopidil dihydrochlorid
Naftopidil DiHCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.
价 格:¥电议型 号:T6600产 地:中国大陆
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TP1288FertirelinInhibitor,Gonadotropin releasing hormone receptor,GNRHR,Fertirelin,GnRH Receptor,inhibit
Fertirelin, or fertirelin acetate, sold under the brand name Ovalyse, is a gonadotropin-releasing hormone agonist (GnRH agonist).
价 格:¥电议型 号:TP1288产 地:中国大陆
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T6576Malotilateinjury,LOX,NKK-105,Inhibitor,collagen,oral,migration,Malotilate,inhibit,hepatotropic,anti-
Malotilate is a medicine used for the therapy of liver cirrhosis.
价 格:¥电议型 号:T6576产 地:中国大陆
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TN6675Cyclo-Val-Pro-diketopiperazine
Cyclo-Val-Pro-diketopiperazine is obtained from the marine fungus and shows moderate antifungal and weak antitumor activities. Cyclo(Pro-Val) inhibits the growth of Bacillus subtilis with MIC of 0.8 g/L.
价 格:¥电议型 号:TN6675产 地:中国大陆
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T7823IDRA-21IDRA-21,memory,Inhibitor,inhibit,orally active,Ionotropic glutamate receptors,IDRA 21,aging,e
IDRA-21 is a positive AMPA receptor modulator.
价 格:¥电议型 号:T7823产 地:中国大陆
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T9256N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamineNCyclohexyl4[1(1piperazinyl)2
N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine is a novel 2,6-naphthyridine identified by high throughput screen (HTS) as a dual protein kinase C/D (PKC/PKD) inhibitor[1].
价 格:¥电议型 号:T9256产 地:中国大陆
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T7405Piperidolateinhibit,Muscarinic acetylcholine receptor,Piperidolate,mAChR,Inhibitor
Piperidolate inhibits intestinal cramp induced by acetylcholine
价 格:¥电议型 号:T7405产 地:中国大陆
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T7744Piperaquine tetraphosphate tetrahydrateartemisinin,Parasite,inhibit,antimalarial,drug-based,Inhibito
Piperaquine tetraphosphate tetrahydrate is a potent anti-parasites agent.
价 格:¥电议型 号:T7744产 地:中国大陆
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T9341Bemnifosbuvirguanosine,pangenotypic,Hepatitis C virus,SARS coronavirus,inhibit,HCV,Bemnifosbuvir,Inh
Bemnifosbuvir is a novel phosphoramidate prodrug of 2´-fluoro-2´-C-methylguanosine-5´-monophosphate that has potent in vitro activity against HCV.
价 格:¥电议型 号:T9341产 地:中国大陆
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T8434SIB-1757SIB-1757,mGluR,SIB1757,Metabotropic glutamate receptors,inhibit,Inhibitor,SIB 1757
SIB-1757 is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)
价 格:¥电议型 号:T8434产 地:中国大陆
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T6774AZD-8835inhibit,PI3K,Inhibitor,AZD 8835,AZD-8835,Phosphoinositide 3-kinase
AZD8835 is a mixed inhibitor of PI3Kα/δ (IC50: 6.2/5.7 nM), also with selectivity against PI3Kβ/γ (IC50: 431/90 nM).
价 格:¥电议型 号:T6774产 地:中国大陆
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T7175Alflutinib mesylatecancer,Epidermal growth factor receptor,AST2818,esistant mutation,Alflutinib,Alfl
AST2818 mesylate,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.
价 格:¥电议型 号:T7175产 地:中国大陆