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T2545Lomitapide MesylateInhibitor,Lomitapide,Lomitapide Mesylate,AEGR-733,inhibit,AEGR 733,BMS-201038,AEG
Lomitapide Mesylate is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
价 格:¥电议型 号:T2545产 地:中国大陆
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TQ0058MI-463MI463,Epigenetic Reader Domain,MI-463,MI 463,Inhibitor,inhibit
MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).
价 格:¥电议型 号:TQ0058产 地:中国大陆
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T9680IrloxacinInhibitor,acid pH,antibacterial agent,Bacterial,gram-positive,oral,Irloxacin,Pirfloxacin,gr
Irloxacin is a new quinolone derivative, and shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria.
价 格:¥电议型 号:T9680产 地:中国大陆
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T8862ML 254ML 254,inhibit,ML254,ML-254,Inhibitor,Metabotropic glutamate receptors,mGluR,Schizophrenia
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinase (DMPK) properties for systemic dosing in rodents.
价 格:¥电议型 号:T8862产 地:中国大陆
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T7468(-?)?-?α-?Terpineolwhite,aroma,monoterpene,wines,(?)??α?Terpineol,Inhibitor,inhibit,( ?)? ?α ?Terpin
α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway
价 格:¥电议型 号:T7468产 地:中国大陆
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T7209MaropitantNK receptor,Maropitant,Tachykinin receptor,inhibit,Neurokinin Receptor,Inhibitor
Maropitant is a selective neurokinin (NK1) receptor antagonist.
价 格:¥电议型 号:T7209产 地:中国大陆
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T8636Ibrutinib deacryloylpiperidineBtk,Bruton tyrosine kinase,Inhibitor,inhibit,Ibrutinib deacryloylpiper
Ibrutinib deacryloylpiperidine is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.
价 格:¥电议型 号:T8636产 地:中国大陆
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T9408N-piperidine IbrutinibN piperidine Ibrutinib,Npiperidine Ibrutinib
N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.
价 格:¥电议型 号:T9408产 地:中国大陆
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T8779HBT1HBT 1,Ionotropic glutamate receptors,HBT-1,BDNF,LBD,inhibit,glutamate,AMPA,primary neurons,S518,
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.
价 格:¥电议型 号:T8779产 地:中国大陆
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T60390PI-55
PI-55 is a specific cytokinin receptor inhibitor. PI-55 is structurally related to 6-benzylaminopurine (BAP) and was shown to inhibit competitively BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3. PI-55 inhibits cytokinins-induced haustorium formation and increased parasite aggressiveness [1].
价 格:¥电议型 号:T60390产 地:中国大陆
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T6352(-)-Dizocilpine maleate(-)-MK 801 (Maleate);C13737;(-)-MK 801 Maleate;(-)-MK 801马来酸
MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
价 格:¥电议型 号:T6352产 地:中国大陆
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T6330LinperlisibPI3Kδ-IN-2
PI3Kδ-IN-2 is a potent and selective inhibitor of PI3Kδ
价 格:¥电议型 号:T6330产 地:中国大陆
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T6316CalcitriolCalcijex;1,25-Dihydroxyvitamin D3;Topitriol;RO215535;Rocaltrol;骨化三醇
Calcitriol is the physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calci
价 格:¥电议型 号:T6316产 地:中国大陆
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T6307Lubiprostone芦比前列酮;鲁比前列酮;RU-0211;SPI-0211
Lubiprostone, an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.
价 格:¥电议型 号:T6307产 地:中国大陆
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T6297Alvespimycin hydrochlorideAlvespimycin (17-DMAG) HCl;NSC 707545;17-DMAG hydrochloride;KOS-1022;BMS 8
17-DMAG is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.
价 格:¥电议型 号:T6297产 地:中国大陆
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T6290TanespimycinKOS 953;17-AAG;CP 127374;NSC 330507;坦螺旋霉素
Tanespimycin (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).
价 格:¥电议型 号:T6290产 地:中国大陆
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T6284OnalespibAT13387;Onalespib (AT13387)
Onalespib is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation
价 格:¥电议型 号:T6284产 地:中国大陆
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T6277DoramapimodBIRB 796;达马莫德;度马莫德
Doramapimod is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
价 格:¥电议型 号:T6277产 地:中国大陆
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T6271TipifarnibZarnestra;IND 58359;R115777;替吡法尼
Tipifarnib is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting
价 格:¥电议型 号:T6271产 地:中国大陆
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T6267Lomitapide洛美他派;AEGR-733;BMS-201038
Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) i
价 格:¥电议型 号:T6267产 地:中国大陆