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T7133Anagliptinlipid‐lowering,smooth muscle cell,SK0403,inhibit,DPP-4,Anagliptin,Dipeptidyl Peptidase,DPP
Anagliptin is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.
价 格:¥电议型 号:T7133产 地:中国大陆
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T6608NMDAinhibit,iGluR,Inhibitor,NMDA,Ionotropic glutamate receptors,Endogenous Metabolite
N-Methyl-D-aspartic acid is an amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors.
价 格:¥电议型 号:T6608产 地:中国大陆
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T9189Iptacopan hydrochlorideLNP 023,hemoglobinuria,inhibit,PNH,Iptacopan hydrochloride,atypical,pathogene
LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM.
价 格:¥电议型 号:T9189产 地:中国大陆
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T7186CZC-8004CZC 8004,HER1,Vascular endothelial growth factor receptor,ErbB-1,Epidermal growth factor rec
CZC-8004 is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
价 格:¥电议型 号:T7186产 地:中国大陆
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TP1410Cecropin ABacterial,Cecropin A,inhibit,Inhibitor,Antibiotic
Cecropin A, a linear 37-residue antimicrobial polypeptide produced by the cecropia moth, has exhibited cytotoxicity in various human cancer cell lines and inhibitory effects on tumor growth.
价 格:¥电议型 号:TP1410产 地:中国大陆
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T64359(E)-1-[(E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl]-3- (3,4,5-trimethoxybenzylidene) piperidin-2-one(E
(E)-1-[(E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl]-3- (3,4,5-trimethoxybenzylidene) piperidin-2-one is an anti-inflammatory agent. It exhibited dose-dependent inhibition of LPS-induced release of TNF-a and IL-6 in active RAW 264.7 mouse macrophages, IC50=3.69uM and 3.68uM, respectively.
价 格:¥电议型 号:T64359产 地:中国大陆
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TN1611Epimedoside AInhibitor,inhibit,Epimedoside A
Epimedoside A has significant antioxidant activity in vitro.
价 格:¥电议型 号:TN1611产 地:中国大陆
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T7511Cyclo(his-pro)Endogenous Metabolite,active,orally,inflammatory,inhibit,tyreotropin-releasing,stress,
Cyclo(his-pro) is an endogenous cyclic dipeptide that exerts oxidative damage protection by selectively activating the transcription factor Nrf2 signalling pathway.
价 格:¥电议型 号:T7511产 地:中国大陆
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T8639Phenibut (hydrochloride)Inhibitor,anxiogenic,Phenibut,inhibit,PEA,neuropsychotropic,Phenibut (hydroc
Phenibut (hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptors, and inhibits the actions of β-phenethylamine
价 格:¥电议型 号:T8639产 地:中国大陆
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TQ0227EtrasimodEtrasimod,APD-334,LPL Receptor,Inhibitor,inhibit,APD 334,Lysophospholipid Receptor
Etrasimod is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50: 1.88 nM in CHO cells).
价 格:¥电议型 号:TQ0227产 地:中国大陆
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T7387Ceftaroline fosamilN-phosphono,PPI 0903,inhibit,TAK599,MRSA,TAK 599,PPI-0903,T-91825,Bacterial,Inhib
Ceftaroline fosamil is a cephalosporin, with activity against Gram-positive pathogens.
价 格:¥电议型 号:T7387产 地:中国大陆
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T97356-(4-methylpiperazin-1-yl)-4-o-tolylnicotinamide6(4methylpiperazin1yl)4otolylnicotinamide,6 (4 methy
6-(4-methylpiperazin-1-yl)-4-o-tolylnicotinamide can be used in the synthesis of befetupitant and netupitant.
价 格:¥电议型 号:T9735产 地:中国大陆
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T8146Imidocarb dipropionateB. bovis,Inhibitor,Imidocarb dipropionate,Anti-protozoan,inhibit,Parasite,Anti
Imidocarb dipropionate is an antigenic insecticide, is active against the protozoan parasite B. bovis (IC50 : 0.87 μg/ml).
价 格:¥电议型 号:T8146产 地:中国大陆
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TN1644Flavanomareinantioxidative,PI3K,antihypertensive,Smad,anti-hyperlipidemic,Flavanomarein,6-hydroxydop
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells treated with free fatty acids (FFAs).
价 格:¥电议型 号:TN1644产 地:中国大陆
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T22345INCB054329Inhibitor,inhibit,INCB 054329,Epigenetic Reader Domain
INCB054329, a structurally distinct bromodomain and extraterminal domain (BET) inhibitor, inhibits BRD2-BD1, BRD2-BD2, BRD3-BD1, BRD3-BD2, BRD4-BD1, BRD4-BD2, BRDT-BD1 and BRDT-BD2 with IC50 values of 44 nM, 5 nM, 9 nM, 1 nM, 28 nM, 3 nM, 119 nM and 63 nM respectively.
价 格:¥电议型 号:T22345产 地:中国大陆
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T10732Tematropium
Tematropium possesses anticholinergic effects and can be used in neurological studies.
价 格:¥电议型 号:T10732产 地:中国大陆
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T8932GSK046GSK046,Epigenetic Reader Domain,BRDT,BRD2,inhibit,immuno-inflammation,GSK 046,GSK-046,BRD4,Inh
GSK046 is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins(IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively). It has immunomodulatory activity.
价 格:¥电议型 号:T8932产 地:中国大陆
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T35530IHMT-PI3Kδ-372IHMTPI3Kδ372,IHMT-PI-3Kδ-372,IHMT PI3Kδ 372
IHMT-PI3Kδ-372 is a selective inhibitor of PI3Kδ with an IC50 of 14 nM and can be used in studies about chronic obstructive pulmonary disease.
价 格:¥电议型 号:T35530产 地:中国大陆
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T9766GW590735lipid,LDLc,GW-590735,GW 590735,HDLc,Peroxisome proliferator-activated receptors,GW590735,PPA
GW590735 is an effective and selective PPARα agonist with an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW590735 can be used in dyslipidemia studies.
价 格:¥电议型 号:T9766产 地:中国大陆
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T7870TCN 201TCN 201,GluN1,Inhibitor,GluN2A,inhibit,iGluR,Ionotropic glutamate receptors,NMDAR,TCN201
TCN-201 is a selective antagonist of NMDA receptors containing the NR2A subunit.
价 格:¥电议型 号:T7870产 地:中国大陆