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  • T80070PKCβII Peptide Inhibitor I；化合物 PKCβII Peptide Inhibitor IPKCβII Peptide Inhibitor I

    PKCβII Peptide Inhibitor I, a specific PKCβII inhibitor, exhibits cardioprotective properties in a rat cardiac ischemia/reperfusion injury model and mitigates vascular endothelial dysfunction [1].

    价 格：￥电议型 号：T80070产 地：中国大陆

  • T80049?-Conotoxin GIIIB；化合物 ?-Conotoxin GIIIB?-Conotoxin GIIIB

    μ-Conotoxin GIIIB, a 22-residue polypeptide derived from the venom of the piscivorous cone snail Conus geographus, serves as an inhibitor of the Na V 1.4 channel, effectively blocking muscle cell contraction [1] [2] [3].

    价 格：￥电议型 号：T80049产 地：中国大陆

  • T80043?-Conotoxin-CnIIIC；化合物 ?-Conotoxin-CnIIIC?-Conotoxin-CnIIIC

    μ-Conotoxin-CnIIIC, a 22-residue conopeptide derived from Conus consors, acts as a potent and persistent NaV1.4 channel blocker, exhibiting analgesic, anaesthetic, and myorelaxant properties [1] [2].

    价 格：￥电议型 号：T80043产 地：中国大陆

  • T80039ATX-II；化合物 ATX-IIATX-II

    ATX-II, an Na+ channel modulator toxin derived from the sea anemone (Anemonia sulcata), causes delayed inactivation of the Na+ channels and has been linked to pulmonary vein arrhythmogenesis and atrial fibrillation [1] [2]. It exhibits interaction with halothane, caffeine, and ryanodine.

    价 格：￥电议型 号：T80039产 地：中国大陆

  • T80025Bovine Type II Collagen；II型胶原蛋白，来源于牛Collagen, Type II, Immunization Grade；Collagen, Type II, Immuniz

    Type II collagen is a protein that demonstrates considerable effectiveness in alleviating pain and inflammation associated with collagen-induced arthritis in mice, with notable application in the treatment of osteoarthritis [1].

    价 格：￥电议型 号：T80025产 地：中国大陆

  • T79983Flaccidoside II；化合物 Flaccidoside IIFlaccidoside II

    Flaccidoside II, an active triterpenoid saponin from Anemone flaccida rhizome, both inhibits proliferation and induces apoptosis in Malignant Peripheral Nerve Sheath Tumors (MPNSTs) cell lines and ameliorates collagen-induced arthritis in mice [1] [2].

    价 格：￥电议型 号：T79983产 地：中国大陆

  • T79980Flaccidoside III；化合物 Flaccidoside IIIFlaccidoside III

    Flaccidoside III, a flavonoid and triterpenoid compound extracted from the aerial parts of N. sativa (Ranunculaceae), demonstrates inhibition of α-Glucosidase (IC50: 256.7 μM) and exhibits potential antioxidant and antidiabetic properties [1].

    价 格：￥电议型 号：T79980产 地：中国大陆

  • T79753hCAIX/XII-IN-8；化合物 hCAIX/XII-IN-8hCAIX/XII-IN-8

    hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.7 nM for CA XII. It demonstrates significant inhibitory efficacy particularly against tumor-associated, membrane-bound isoforms hCA IX and XII, while exhibiting a high selectivity over the cytosolic isoforms hCA I and II [1].

    价 格：￥电议型 号：T79753产 地：中国大陆

  • T79748hCAIX/XII-IN-7；化合物 hCAIX/XII-IN-7hCAIX/XII-IN-7

    Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM for hCA IX and 59 nM for hCA XII, while also showing activity against hCA I and II with Kis of 3.2 nM and 9.2 nM, respectively. It holds potential for research into hypoxic tumors [1].

    价 格：￥电议型 号：T79748产 地：中国大陆

  • T79718CaMKIIα-PHOTAC；化合物 CaMKIIα-PHOTACCaMKIIα-PHOTAC

    CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα). This molecule facilitates the ubiquitination and subsequent proteasome-mediated degradation of CaMKIIα when exposed to certain light wavelengths. Under illumination, CaMKIIα-PHOTAC diminishes synaptic functions and weakens evoked field excitatory postsynaptic potentials in the mouse hippocampus, thus impacting physiological responses. Additionally, it i

    价 格：￥电议型 号：T79718产 地：中国大陆

  • T79539Topoisomerase II inhibitor 16；化合物 Topoisomerase II inhibitor 16Topoisomerase II inhibitor 16

    Topoisomerase II Inhibitor 16 (compound CT3) is a selective, orally bioavailable, and irreversible inhibitor of trypanosomal topoisomerase II, possessing the ability to penetrate the brain and stabilize double-stranded DNA-enzyme cleavage complexes. It shows promise for research into Chagas disease [1].

    价 格：￥电议型 号：T79539产 地：中国大陆

  • T79506Topoisomerase II inhibitor 15；化合物 Topoisomerase II inhibitor 15Topoisomerase II inhibitor 15

    Topoisomerase II inhibitor 15 (compound 2g) serves as a potent apoptotic inducer, exhibiting heightened selectivity for head and neck tumors [1].

    价 格：￥电议型 号：T79506产 地：中国大陆

  • T7944VPS34 inhibitor 1 (Compound 19, PIK-III analogue)；化合物VPS34PIK-III analogue；PIK-III analogue

    VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)

    价 格：￥电议型 号：T7944产 地：中国大陆

  • T79411hCAXII-IN-7；化合物 hCAXII-IN-7hCAXII-IN-7

    hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability. Moreover, it promotes apoptosis in 786-0, SF-539, and HS 578 T cell lines [1].

    价 格：￥电议型 号：T79411产 地：中国大陆

  • T79378IIIM-8；化合物 IIIM-8IIIM-8

    IIIM-8 is a melanogenesis inhibitor that suppresses pigment production in both in vitro and in vivo settings, exhibiting no cytotoxic effects on Human Adult Epidermal Melanocytes (HAEM). It has potential applications in the study of hyperpigmentation disorders [1].

    价 格：￥电议型 号：T79378产 地：中国大陆

  • T79351JH-XII-03-02；化合物 JH-XII-03-02JH-XII-03-02

    JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson´s Disease (PD) research [1].

    价 格：￥电议型 号：T79351产 地：中国大陆

  • T79290SRE-II；化合物 SRE-IISRE-II

    SRE-II, an amide derivative, serves as an activatable photosensitizer tailored for photodynamic cancer research, exhibiting diminished fluorescence and photosensitizing properties. Upon carboxylesterase-catalyzed amide bond cleavage, it transforms into its active form, SDU Red. In light-exposed environments, SRE-II prompts DNA damage and induces cell apoptosis, highlighting its potential as a theranostic agent for triple-negative breast cancer [1].

    价 格：￥电议型 号：T79290产 地：中国大陆

  • T79008Ys-II；化合物 Ys-IIYs-II

    Compound 1 (Ys-II) is a spirostanol glycoside extracted from the stem of Yucca elephantipes, exhibiting antifungal properties by inhibiting Candida albicans and Cryptococcus neoformans growth with IC50 values of 5 and 6 μg/mL, respectively [1].

    价 格：￥电议型 号：T79008产 地：中国大陆

  • T78789hCA XII-IN-6；化合物 hCA XII-IN-6hCA XII-IN-6

    Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferative effects, making it useful in cancer research [1].

    价 格：￥电议型 号：T78789产 地：中国大陆

  • T78729hCAIX/VII-IN-1；化合物 hCAIX/VII-IN-1hCAIX/VII-IN-1

    hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX. It displays inhibitory activity against hCA I, II, IV, VII, and IX, with respective K_i values of 336.2 nM, 185.8 nM, 1055 nM, 35.6 nM, and 28.0 nM. This compound is applicable in cancer and neurological disease research [1].

    价 格：￥电议型 号：T78729产 地：中国大陆

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