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T14205AM679;化合物 T14205AM679
AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively. IC50 value: 2.2 nM/0.6 nM/154 nM(FLAP binding/hLA/hWB) [1] AM679 showed an improved CYP inhibition profile (IC50 3A4 = 16.7 lM, 2C9 = 3.7 lM, 2D6 >30 lM), no time dependent inhibition against CYP3A4 (0.003 min-1 vs 0.057 min-1 for troleandomycin control 10 uM) and no CYP3A4 induction. AM679 has an excellent hWB IC50 potency of 154 nM. Target: FLAP in vitro: AM679 showed excell
价 格:¥电议型 号:T14205产 地:中国大陆
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T14203AM-8735;化合物 T14203AM-8735
AM-8735 is an inhibitor of MDM2 ( IC50: 25 nM).
价 格:¥电议型 号:T14203产 地:中国大陆
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T14202AM-4668;化合物 T14202AM-4668
AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively.
价 格:¥电议型 号:T14202产 地:中国大陆
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T14201AM-2099;化合物 T14201AM-2099
AM-2099 is a voltage-gated sodium channel Nav1.7 inhibitor (IC50: 0.16 μM).
价 格:¥电议型 号:T14201产 地:中国大陆
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T14200AM-1638;化合物 T14200AM-1638
AM-1638 is a full agonist of GPR40/FFA1 (EC50: 0.16 μM).
价 格:¥电议型 号:T14200产 地:中国大陆
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T1420Diethylcarbamazine citrate;枸橼酸乙胺嗪Caritrol|||Loxuran|||Dicarocide;Caritrol|||枸橼酸乙胺嗪|||Loxuran|||Dicar
Diethylcarbamazine citrate (Caritrol) is an anthelmintic used primarily as the citrate in the treatment of filariasis, particular infestations with Wucheria bancrofti or Loa loa. It is an inhibitor of arachidonic acid metabolism in filarial microfilaria.
价 格:¥电议型 号:T1420产 地:中国大陆
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T14142AGL-2263;化合物 T14142AGL-2263
AGL-2263 is a blocker of insulin receptor (IR)
价 格:¥电议型 号:T14142产 地:中国大陆
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T14077A-935142;化合物A-935142A-935142
A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator. a-935142 enhances hERG currents by slowing inactivation, promoting activation, reducing inactivation, shortening atrial and ventricular repolarization, and in a complex manner.
价 格:¥电议型 号:T14077产 地:中国大陆
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T140142-(Biotin-amido)-1,3-bis-(C1-PEG1-acid);化合物 T140142-(Biotin-amido)-1,3-bis-(C1-PEG1-acid)
2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker utilized in the synthesis of PROTACs[1].
价 格:¥电议型 号:T14014产 地:中国大陆
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T13760Lurasidone Metabolite 14283 hydrochloride;化合物 T13760Lurasidone Metabolite 14283 hydrochloride
Lurasidone Metabolite 14283 hydrochloride is a major active metabolite of Lurasidone.
价 格:¥电议型 号:T13760产 地:中国大陆
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T13564L2AZ7550 trimesylate salt;AZ7550甲磺酸盐AZ7550 Mesylate|||AZ7550 trimesylate salt (1421373-99-0 free base)
AZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 trimesylate salt inhibits IGF1R activity and can be used in the study of non-small cell lung cancer.
价 格:¥电议型 号:T13564L2产 地:中国大陆
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T13564LAZ7550 hydrochloride;化合物AZ7550 hydrochlorideAZ7550 hydrochloride (1421373-99-0 free base);AZ7550 hyd
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
价 格:¥电议型 号:T13564L产 地:中国大陆
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T13142LTheodrenaline hydrochloride;茶碱那林盐酸盐Theodrenaline hydrochloride(13460-98-5 Free base);Theodrenaline h
Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.
价 格:¥电议型 号:T13142L产 地:中国大陆
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T1314293,20-dihydroxypregnan-6-one;化合物 3,20-dihydroxypregnan-6-one3,20-dihydroxypregnan-6-one
3,20-dihydroxypregnan-6-one is a useful organic compound for research related to life sciences and the catalog number is T131429.
价 格:¥电议型 号:T131429产 地:中国大陆
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T1314283,20-dioxopregn-4-en-21-yl acrylate;化合物 3,20-dioxopregn-4-en-21-yl acrylate3,20-dioxopregn-4-en-21-y
3,20-dioxopregn-4-en-21-yl acrylate is a useful organic compound for research related to life sciences and the catalog number is T131428.
价 格:¥电议型 号:T131428产 地:中国大陆
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T131426Strophanthidin (Corchorin);化合物 Strophanthidin (Corchorin)Strophanthidin (Corchorin)
Strophanthidin (Corchorin) is a useful organic compound for research related to life sciences and the catalog number is T131426.
价 格:¥电议型 号:T131426产 地:中国大陆
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T13142521-diazo-20-oxopregn-5-en-3-yl acetate;化合物 21-diazo-20-oxopregn-5-en-3-yl acetate21-diazo-20-oxopreg
21-diazo-20-oxopregn-5-en-3-yl acetate is a useful organic compound for research related to life sciences and the catalog number is T131425.
价 格:¥电议型 号:T131425产 地:中国大陆
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T1314246-methyltetrahydro-2H-pyran-2,4,5-triol;化合物 6-methyltetrahydro-2H-pyran-2,4,5-triol6-methyltetrahydr
6-methyltetrahydro-2H-pyran-2,4,5-triol is a useful organic compound for research related to life sciences and the catalog number is T131424.
价 格:¥电议型 号:T131424产 地:中国大陆
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T131422D20,23-3a,12a-diacetoxy-24,24-diphenylcholadiene;化合物 D20,23-3a,12a-diacetoxy-24,24-diphenylcholadien
D20,23-3a,12a-diacetoxy-24,24-diphenylcholadiene is a useful organic compound for research related to life sciences and the catalog number is T131422.
价 格:¥电议型 号:T131422产 地:中国大陆
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T1314212-oxo-3-(3,4,5-trimethoxyphenyl)propanoic acid;化合物 2-oxo-3-(3,4,5-trimethoxyphenyl)propanoic acid2-o
2-oxo-3-(3,4,5-trimethoxyphenyl)propanoic acid is a useful organic compound for research related to life sciences and the catalog number is T131421.
价 格:¥电议型 号:T131421产 地:中国大陆