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T6172MRS 2578MRS 2578
MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.
价 格:¥电议型 号:T6172产 地:美洲
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T6293Mycophenolate MofetilMycophenolate Mofetil,TM-MMF,RS 61443
Mycophenolate mofetil, an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
价 格:¥电议型 号:T6293产 地:美洲
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T6482Efaproxiral SodiumEfaproxiral Sodium,RSR13 sodium,
Efaproxiral Sodium ,a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer.
价 格:¥电议型 号:T6482产 地:美洲
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T8476RSVA405;化合物RSVA 405RSVA 405;RSVA 405
RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor
价 格:¥电议型 号:T8476产 地:中国大陆
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T83766Moexiprilat;化合物 MoexiprilatRS 10029;RS 10029
Moexiprilat, an active metabolite of the prodrug moexipril formed through side chain ester hydrolysis in vivo, functions as an angiotensin-converting enzyme (ACE; IC50 = 2.1 nM) inhibitor. At a concentration of 10 nM, it inhibits the proliferation of primary neonatal rat cardiac fibroblasts stimulated by estrone or angiotensin II. Furthermore, when given at a daily dosage of 50 mg/kg, moexiprilat reduces mean arterial blood pressure and elevates levels of atrial natriuretic peptide, an indicator
价 格:¥电议型 号:T83766产 地:中国大陆
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T83716KSL-128114 TFA;化合物 KSL-128114 TFAAc-rRrGrKkRrSHWX1X2DI-OH (X1=tert-Leucine; X2=Cyclohexylglycine);Ac
KSL-128114, a peptide inhibitor of the membrane regulator syntenin (Ki = 300 nM), notably diminishes the viability of A2058 melanoma and patient-derived glioblastoma multiforme (GBM) cells in a concentration-dependent manner. Furthermore, when administered at 50 ?M, KSL-128114 elevates survival times in a patient-derived xenograft (PDX) mouse model of GBM, where mice were implanted intracranially with patient-derived GBM cells pre-cultured with KSL-128114.
价 格:¥电议型 号:T83716产 地:中国大陆
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T833922a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid;化合物 2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic a
2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid (compound 3), a triterpenoid, markedly reduces fibronectin levels by 27.66% at a concentration of 10 μM in HK-2 cells subjected to high-glucose and TGF-b1 induction [1].
价 格:¥电议型 号:T83392产 地:中国大陆
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T833732α,3β,24-Trihydroxyurs-12-en-28-oic acid;化合物 2α,3β,24-Trihydroxyurs-12-en-28-oic acid2,24-Dihydroxyu
2α,3β,24-Trihydroxyurs-12-en-28-oic acid, a natural product, is isolated from Salvia palaestina [1].
价 格:¥电议型 号:T83373产 地:中国大陆
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T833643-Acetyl-11-keto-ursolic acid;化合物 3-Acetyl-11-keto-ursolic acid3-Acetyl-11-keto-ursolic acid
3-Acetyl-11-keto-ursolic acid (Compound 18), a triterpenoid derived from Eriobotrya japonica leaves, exhibits 11B-hydroxysteroid dehydrogenase 1 (11b-HSD1) inhibitory activity and holds potential for anti-diabetes research [1].
价 格:¥电议型 号:T83364产 地:中国大陆
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T833403α-Acetoxyurs-5:12-dien-24-oic acid;化合物 3α-Acetoxyurs-5:12-dien-24-oic acid3α-Acetoxyurs-5:12-dien-2
3α-Acetoxyurs-5:12-dien-24-oic acid, a natural compound, is isolatable from Boswellia sacra Fluckiger [1].
价 格:¥电议型 号:T83340产 地:中国大陆
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T83160Agarsenone;化合物 AgarsenoneAgarsenone
Agarsenone, a juniperine sesquiterpene, is derived from the resin of Commiphora erythraea.
价 格:¥电议型 号:T83160产 地:中国大陆
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T82994Anzurstobart;化合物 AnzurstobartBMS-986351|||CC-95251;BMS-986351|||CC-95251
Anzurstobart (CC-95251; BMS-986351), a fully human monoclonal anti-SIRPα antibody with high affinity, inhibits CD47-SIRPα interaction. It potentiates macrophage-mediated phagocytosis of DLBCL cell lines in co-culture assays with Rituximab and shows promise in solid and hematologic malignancy research [1].
价 格:¥电议型 号:T82994产 地:中国大陆
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T8277Forsythoside I;连翘酯苷IForsythoside I
Forsythoside I, a caffeoyl phenylethanoid glycoside (CPG), may possess anti-inflammatory activities.
价 格:¥电议型 号:T8277产 地:中国大陆
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T82673CPF-7;化合物 CPF-7Caerulein precursor fragment;Caerulein precursor fragment
CPF-7 (Caerulein precursor fragment), an insulinotropic peptide, promotes insulin secretion and drives epithelial-mesenchymal transition via Snai1 upregulation in PANC-1 ductal cells. Moreover, it induces exocrine plasticity through Ngn3 upregulation, with applications in type 2 diabetes research [1] [2].
价 格:¥电议型 号:T82673产 地:中国大陆
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T82613Danburstotug;化合物 DanburstotugSTI-3031|||IMC-001;STI-3031|||IMC-001
Danburstotug (IMC-001), an immunostimulant and antineoplastic [1], is a humanized IgG1-lambda monoclonal antibody targeting CD274 (PDL1, B7 homologue 1, B7H1).
价 格:¥电议型 号:T82613产 地:中国大陆
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T82607Dazdotuftide;化合物 DazdotuftideTRS01;TRS01
Dazdotuftide is an active immunomodulatory compound [1].
价 格:¥电议型 号:T82607产 地:中国大陆
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T82584Denthyrsinin;化合物 DenthyrsininDenthyrsinin
Denthyrsinin, a phenanthrene [1], exhibits properties consistent with this class of aromatic hydrocarbons, characterized by a fused three-ring structure.
价 格:¥电议型 号:T82584产 地:中国大陆
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T82486Ekersenin;化合物 EkerseninEkersenin
Ekersenin, a natural product, is isolated from the plant Ekererbegia senegalensis [1].
价 格:¥电议型 号:T82486产 地:中国大陆
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T82461Epacmarstobart;化合物 EpacmarstobartGS-0189|||FSI-189;GS-0189|||FSI-189
Epacmarstobart (FSI-189; GS-0189) is a chimeric humanized IgG1κ antibody designed to target the mouse Signal Regulatory Protein Alpha (SIRPA).
价 格:¥电议型 号:T82461产 地:中国大陆
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T82426Evazarsen;化合物 EvazarsenISIS-757456;ISIS-757456
Evazarsen, an angiotensinogen synthesis inhibitor, exhibits antihypertensive properties [1].
价 格:¥电议型 号:T82426产 地:中国大陆