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T79659SARS-CoV-2 3CLpro-IN-16；SARS-CoV-2 3CLpro 抑制剂16SARS-CoV-2 3CLpro-IN-16
SARS-CoV-2 3CLpro-IN-16 is a covalent SARS-CoV-2 3CLpro inhibitor that inhibits 3CLpro activity and achieves its inhibitory effect by forming a covalent bond with Cys145.
价 格：￥电议型 号：T79659产 地：中国大陆
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T79570SARS-CoV-2-IN-55；化合物 SARS-CoV-2-IN-55SARS-CoV-2-IN-55
SARS-CoV-2-IN-55 (compound 65) is an inhibitor of SARS-CoV-2 exhibiting low cytotoxicity, characterized by an IC50 of 0.3 μM, effectuated through direct interaction with VSV-S pseudoparticles [1].
价 格：￥电议型 号：T79570产 地：中国大陆
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T79526SARS-CoV-2 nsp14-IN-4；化合物 SARS-CoV-2 nsp14-IN-4SARS-CoV-2 nsp14-IN-4
SARS-CoV-2 nsp14-IN-4 (Compound 12q), a non-cytotoxic and cell-permeable inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50 = 19 nM), is employed in COVID-19 research [1].
价 格：￥电议型 号：T79526产 地：中国大陆
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T79515SARS-CoV-2 Mpro-IN-10；化合物 SARS-CoV-2 Mpro-IN-10SARS-CoV-2 Mpro-IN-10
SARS-CoV-2 Mpro-IN-10 (27h) is a potent inhibitor of the Mpro enzyme, exhibiting IC50 and EC50 values of 10.9 nM and 43.6 nM, respectively. It is utilized in research focused on the SARS-CoV-2 virus [1].
价 格：￥电议型 号：T79515产 地：中国大陆
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T79470RORγt inverse agonist 31；化合物 RORγt inverse agonist 31RORγt inverse agonist 31
RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), exhibiting an inhibitory concentration (IC50) of 0.428 μM. It has demonstrated efficacy in mitigating Imiquimod-induced psoriasis severity in murine models [1].
价 格：￥电议型 号：T79470产 地：中国大陆
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T79462SARS-CoV-2 3CLpro-IN-14；化合物 SARS-CoV-2 3CLpro-IN-14SARS-CoV-2 3CLpro-IN-14
SARS-CoV-2 3CLpro-IN-14 (compound 11j) is an orally active inhibitor of SARS-CoV-2 3CLpro, demonstrating potent anti-SARS-CoV-2 properties with an EC50 of 0.18 μM and exhibits minimal cytotoxicity, having a CC50 greater than 50 μM, in Vero E6 cells [1].
价 格：￥电议型 号：T79462产 地：中国大陆
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T79455SARS-CoV-2 Mpro-IN-9；化合物 SARS-CoV-2 Mpro-IN-9SARS-CoV-2 Mpro-IN-9
SARS-CoV-2 Mpro-IN-9 (compound c7), a nonpeptidic, noncovalent inhibitor of SARS-CoV-2 main protease (Mpro), exhibits potent inhibitory action (IC50 = 0.085 μM) and improved physicochemical and drug metabolism and pharmacokinetics (DMPK) properties. It effectively suppresses viral replication in SARS-CoV-2-infected Vero E6 cells (EC50 = 1.10 μM) and demonstrates low cytotoxicity (CC50 > 50 μM) [1].
价 格：￥电议型 号：T79455产 地：中国大陆
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T79426SARS-CoV-2-IN-61；化合物 SARS-CoV-2-IN-61SARS-CoV-2-IN-61
SARS-CoV-2-IN-61 (compound 8i) is a potent inhibitor of the SARS-CoV-2 PLpro, exhibiting an IC50 of 16 ?M and demonstrating antiviral activities [1].
价 格：￥电议型 号：T79426产 地：中国大陆
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T79414SARS-CoV-2-IN-60；化合物 SARS-CoV-2-IN-60SARS-CoV-2-IN-60
SARS-CoV-2-IN-60 (compound 5a) is a specific, irreversible inhibitor of SARS-CoV-2 nsp16-nsp10 methyltransferase, competing with S-adenosylmethionine (SAM) and exhibiting an IC50 of 9 ?M and a Ki of 26 ?M. It binds to a novel pocket near the SAM-binding site on nsp16, suggesting potential as a pan-coronavirus therapeutic [1].
价 格：￥电议型 号：T79414产 地：中国大陆
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T79376SARS-CoV-2 3CLpro-IN-19；化合物 SARS-CoV-2 3CLpro-IN-19SARS-CoV-2 3CLpro-IN-19
SARS-CoV-2 3CLpro-IN-19 (Compound C5a), a non-covalent, non-peptide inhibitor of the SARS-CoV-2 3CLpro enzyme, exhibits potent in vitro activity with an IC50 of 0.7 μM. It demonstrates broad-spectrum efficacy against infection by Omicron subvariants (BA.5, BQ.1.1, and XBB.1.5) in human cells, with EC50 values ranging from 30-69 nM [1].
价 格：￥电议型 号：T79376产 地：中国大陆
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T79356SARS-CoV-2-IN-57；化合物 SARS-CoV-2-IN-57SARS-CoV-2-IN-57
SARS-CoV-2-IN-57 (compound (+)-R-26) is a potent inhibitor of SARS-CoV-2 with an IC50 of 80 nM and demonstrates high affinity for the Sigma Receptor, exhibiting Kis of 13.6 nM (S1R) and 14.4 nM (S2R) [1].
价 格：￥电议型 号：T79356产 地：中国大陆
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T79329SARS-CoV-2-IN-56；化合物 SARS-CoV-2-IN-56SARS-CoV-2-IN-56
SARS-CoV-2-IN-56 (Compound 63) is a SARS-CoV-2 inhibitor with antiviral activity, demonstrating inhibition of the virus in Vero E6 cells with an IC50 of 0.7 μM [1].
价 格：￥电议型 号：T79329产 地：中国大陆
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T79328SARS-CoV-2-IN-54；化合物 SARS-CoV-2-IN-54SARS-CoV-2-IN-54
SARS-CoV-2-IN-54 (Compound 2), a SARS-CoV-2 inhibitor, exhibits antiviral activity by impeding the virus in Vero E6 cells with an inhibitory concentration (IC50) of 21.4 μM [1].
价 格：￥电议型 号：T79328产 地：中国大陆
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T79326MRS7925；化合物 MRS7925MRS7925
MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosis [1].
价 格：￥电议型 号：T79326产 地：中国大陆
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T79310SARS-CoV-2-IN-53；化合物 SARS-CoV-2-IN-53SARS-CoV-2-IN-53
ARS-CoV-2-IN-53 (Compd 5d) exhibits an inhibitory effect on SARS-CoV-2 replication, with an effective concentration (EC50) value of 14.3 μM, and demonstrates notable antiviral activity against human coronavirus 229E (HCoV-229E) [1].
价 格：￥电议型 号：T79310产 地：中国大陆
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T79279SARS-CoV-2 Mpro-IN-8；化合物 SARS-CoV-2 Mpro-IN-8SARS-CoV-2 Mpro-IN-8
SARS-CoV-2 Mpro-IN-8 (compound 6b) is an antiviral agent effective against SARS-CoV-2 [1].
价 格：￥电议型 号：T79279产 地：中国大陆
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T79278SARS-CoV-2 Mpro-IN-7；化合物 SARS-CoV-2 Mpro-IN-7SARS-CoV-2 Mpro-IN-7
SARS-CoV-2 Mpro-IN-7 (compound 6g) effectively inhibits SARS-CoV-2 main protease (Mpro) with an IC50 value of 8.8 μM and exhibits a cytotoxic concentration (CC50) of 10 μM [1].
价 格：￥电议型 号：T79278产 地：中国大陆
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T79245SARS-CoV-2-IN-45；化合物 SARS-CoV-2-IN-45SARS-CoV-2-IN-45
SARS-CoV-2-IN-45 (Compound 8p) serves as an inhibitor of SARS-CoV-2, effectively hindering viral replication in Calu-3 cells with an EC50 value of 0.5 μM and exhibiting negligible cytotoxic effects [1].
价 格：￥电议型 号：T79245产 地：中国大陆
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T79244SARS-CoV-2-IN-44；化合物 SARS-CoV-2-IN-44SARS-CoV-2-IN-44
SARS-CoV-2-IN-44, an inhibitor of SARS-CoV-2, effectively suppresses viral replication with an EC50 value of 0.6μM and exhibits negligible cytotoxicity in Calu-3 cells, rendering it suitable for antiviral research [1].
价 格：￥电议型 号：T79244产 地：中国大陆
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T79243SARS-CoV-2-IN-43；化合物 SARS-CoV-2-IN-43SARS-CoV-2-IN-43
Compound 8h, also known as SARS-CoV-2-IN-43, is a powerful inhibitor effective in obstructing the replication of SARS-CoV-2, exhibiting significant antiviral activity [1].
价 格：￥电议型 号：T79243产 地：中国大陆
