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T81202SARS-CoV-2-IN-69;化合物 SARS-CoV-2-IN-69SARS-CoV-2-IN-69
SARS-CoV-2-IN-69 (Compound 7E) is a potent, non-covalent inhibitor of the SARS-CoV-2 main protease (M^pro) with an EC50 of 7.4 μM and also inhibits the papain-like protease (PL^pro) [1].
价 格:¥电议型 号:T81202产 地:中国大陆
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T81186SDGR;化合物 SDGRSDGR
SDGR, a tetrapeptide comprising a serine-aspartic acid-glycine-arginine (Ser-Asp-Gly-Arg) sequence, efficiently impedes cell attachment mediated by fibronectin [1].
价 格:¥电议型 号:T81186产 地:中国大陆
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T81177Ser@TPP@CUR;化合物 Ser@TPP@CURSer@TPP@CUR
Ser nM TPP nM CUR, a derivative of Curcumin, notably mitigates damage in renal tubular epithelial cells and enhances renal function in mice with acute kidney injury (AKI). This compound holds potential for AKI research applications [1].
价 格:¥电议型 号:T81177产 地:中国大陆
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T81115sPLA2-IIA Inhibitor;化合物 sPLA2-IIA InhibitorsPLA2-IIA Inhibitor
The sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK, specifically cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2), which interacts with human IIA phospholipase A2 (hGIIA) to impede its ester bond hydrolyzing function. As part of the esterase superfamily, sPLA2 enzymatically cleaves the sn-2 ester bond in glycerophospholipids, releasing arachidonic acid and lysophospholipids[1].
价 格:¥电议型 号:T81115产 地:中国大陆
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T81027TCRS-417;化合物 TCRS-417T417;T417
TCRS-417 (T417), a small molecule compound, selectively binds to the interface between PBX1 and its specific DNA target sequence, disrupting the PBX1-DNA interaction. This compound has potential research applications in cancer, developmental, inflammatory, autoimmune, and neurodegenerative diseases [1].
价 格:¥电议型 号:T81027产 地:中国大陆
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T80918Tuparstobart;化合物 TuparstobartIncagn-02385;Incagn-02385
Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on activated T cells, NK cells, B cells, and plasmacytoid dendritic cells [1].
价 格:¥电议型 号:T80918产 地:中国大陆
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T80869Versicolactone B;化合物 Versicolactone BVersicolactone B
Versicolactone B, a sesquiterpene extracted from Viola yedoensis, exhibits anti-complement activity affecting both the classical and alternative pathways [1].
价 格:¥电议型 号:T80869产 地:中国大陆
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T80695β-Amyloid precursor protein (96-110), cyclized (human);化合物 β-Amyloid precursor protein (96-110), cyc
β-Amyloid precursor protein (96-110), cyclized (human), a segment of the amyloid precursor protein, serves as a research tool in Alzheimer’s disease studies [1].
价 格:¥电议型 号:T80695产 地:中国大陆
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T80657SARS-CoV-2 3CLpro-IN-15;化合物 SARS-CoV-2 3CLpro-IN-15SARS-CoV-2 3CLpro-IN-15
SARS-CoV-2 3CLpro-IN-15 (compound a), a beta-nitrostyrene derivative, acts as an inhibitor of the SARS-CoV-2 3CL protease (3CLpro), effectively inhibiting viral replication and transcription. It is instrumental in the identification of potential anti-COVID-19 lead compounds [1].
价 格:¥电议型 号:T80657产 地:中国大陆
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T80636SARS-CoV-2-IN-59;4-(4,5-二氢-2-咪唑基)苯腈SARS-CoV-2-IN-59
SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule that inhibits SARS-CoV-2 by targeting its main protease (Mpro). It exhibits robust binding with Mpro residues (Met 165, Gln 166, Met 165, His 41, Gln 189) [1].
价 格:¥电议型 号:T80636产 地:中国大陆
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T80590Cinrebafusp alfa;化合物 Cinrebafusp alfaPRS 343;PRS 343
Cinrebafusp alfa (PRS 343) is an anticalin-based bispecific drug with high affinity for both CD137/HER2, displaying dissociation constants (Kd) of 0.3 nM to recombinant human HER2 and 5 nM to human monomeric CD137 (4-1BB). It promotes T-cell costimulation via tumor-localized, HER2-mediated 4-1BB clustering and activation, thereby enhancing T-cell receptor-driven responses and facilitating tumor cell eradication. This compound shows promising potential in research concerning HER2-positive solid t
价 格:¥电议型 号:T80590产 地:中国大陆
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T80587Alunacedase alfa;化合物 Alunacedase alfaHrsACE2|||GSK 2586881;HrsACE2|||GSK 2586881
Alunacedase alfa (HrsACE2; GSK 2586881), a genetically modified human recombinant soluble angiotensin-converting enzyme-2 (hrsACE2), inhibits SARS-CoV-2 cell entry by competing with membrane-bound ACE2, offering potential in the research of SARS-CoV-2 [1] [2].
价 格:¥电议型 号:T80587产 地:中国大陆
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T80377Xenopsin precursor fragment;化合物 Xenopsin precursor fragmentXenopsin precursor fragment
Xenopsin precursor fragment, an antimicrobial peptide, exhibits both antibacterial/antifungal activity at concentrations ranging from 10 to 500 μg/mL and anti-protozoal activity with a minimum inhibitory concentration (MIC) of 2 to 20 μg/mL [1].
价 格:¥电议型 号:T80377产 地:中国大陆
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T8028Farnesyl acetate;乙酸法呢醇酯Farnesyl Acetate (mixture of isomers);Farnesyl Acetate (mixture of isomers)||
Farnesyl acetate (Farnesyl Acetate (mixture of isomers)) is a flavouring compound identified in foods such as blueberries.
价 格:¥电议型 号:T8028产 地:中国大陆
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T79778Anti-MRSA agent 8;化合物 Anti-MRSA agent 8Anti-MRSA agent 8
Anti-MRSA Agent 8 (Compound 7g), a derivative of DAPG, exhibits potent antibacterial properties by interacting with bacterial cell membranes and is useful for studying methicillin-resistant Staphylococcus aureus (MRSA) [1].
价 格:¥电议型 号:T79778产 地:中国大陆
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T79703RyRs activator 3;化合物 RyRs activator 3RyRs activator 3
RyRs activator 3 (compound A4) serves as an insecticide highly effective against both the diamondback moths, M. separata and P. xylostella. It exhibits an LC50 of 3.27 mg/L for controlling diamondback moth populations. The mechanism of action involves binding to the ryanodine receptor, which elevates cytoplasmic Ca2+ concentration, resulting in biological toxicity [1].
价 格:¥电议型 号:T79703产 地:中国大陆
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T79677SARS-CoV-2-IN-58;化合物 SARS-CoV-2-IN-58SARS-CoV-2-IN-58
SARS-CoV-2-IN-58 (Compound 21H) serves as an antiviral agent targeting SARS-CoV-2, demonstrating efficacy with an EC50 of 18 μM. It specifically inhibits the SARS-CoV-2 main protease (Mpro) with an IC50 value of 0.35 μM [1].
价 格:¥电议型 号:T79677产 地:中国大陆
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T79676SARS-CoV-2 3CLpro-IN-21;化合物 SARS-CoV-2 3CLpro-IN-21SARS-CoV-2 3CLpro-IN-21
SARS-CoV-2 3CLpro-IN-21 (Compound D6) is an irreversible, covalent inhibitor of SARS-CoV-2 3CL pro, demonstrating potent inhibition with an IC50 of 0.03 μM. Additionally, it exhibits inhibitory activity against SARS-CoV-1 3CL pro with an IC50 of 0.12 μM [1].
价 格:¥电议型 号:T79676产 地:中国大陆
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T79661SARS-CoV-2 3CLpro-IN-18;化合物 SARS-CoV-2 3CLpro-IN-18SARS-CoV-2 3CLpro-IN-18
SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent inhibitor of SARS-CoV-2 3CLpro with an IC50 of 0.478 μM. It demonstrates inhibition of SARS-CoV-2 in Vero E6 cells, with an EC50 of 2.499 μM, and exhibits low cytotoxicity (CC50 > 200 μM) [1].
价 格:¥电议型 号:T79661产 地:中国大陆
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T79660SARS-CoV-2 3CLpro-IN-17;化合物 SARS-CoV-2 3CLpro-IN-17SARS-CoV-2 3CLpro-IN-17
Compound 3h, also known as SARS-CoV-2 3CLpro-IN-17, is a selective inhibitor of the SARS-CoV-2 3CL protease, demonstrating an IC50 of 0.322 μM [1].
价 格:¥电议型 号:T79660产 地:中国大陆