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T17435Amino-PEG4-Val-Cit-PAB-MMAE;化合物 T17435Amino PEG4 Val Cit PAB MMAE|||Amino-PEG-4-Val-Cit-PAB-MMAE|||A
Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable tetraethylene glycol (4 unit PEG) antibody-drug conjugate (ADC) linker employed in the synthesis of ADCs[1].
价 格:¥电议型 号:T17435产 地:中国大陆
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T17415Amino-PEG16-acid;化合物 T17415Amino-PEG16-acid
Amino-PEG16-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17415产 地:中国大陆
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T17385Ald-Ph-amido-PEG3-C2-Pfp ester;化合物 T17385Ald-Ph-amido-PEG3-C2-Pfp ester
Ald-Ph-amido-PEG3-C2-Pfp ester is a noncleavable antibody-drug conjugate (ADC) linker that falls under the category of polyethylene glycol (PEG) linkers.
价 格:¥电议型 号:T17385产 地:中国大陆
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T17375Ald-Ph-PEG24-NHS ester;化合物 T17375Ald-Ph-PEG24-NHS ester
Ald-Ph-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17375产 地:中国大陆
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T17365Ala-Ala-Asn-PAB;化合物 T17365Ala-Ala-Asn-PAB
Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17365产 地:中国大陆
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T17355Acid-PEG4-S-PEG4-acid;化合物 T17355Acid-PEG4-S-PEG4-acid
Acid-PEG4-S-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17355产 地:中国大陆
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T17245VU0467485化合物 T17245AZ13713945
VU0467485 is a potent and selective muscarinic acetylcholine receptor 4 positive allosteric modulator. VU0467485 potentiates the activity of ACh at M4 (EC50s: 26.6 nM and 78.8 nM at the rat and human M4 receptors, respectively). VU0467485 displays selectivity for M4 over human and rat M1/2/3/5.
价 格:¥电议型 号:T17245产 地:中国大陆
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T16129MPI_5a;化合物MPI_5aMPI_5a
MPI_5a is an effective and selective inhibitor of HDAC6 (IC50=36 nM). MPI_5a weakly inhibits other HDAC isoforms and it also inhibits acyl-tubulin accumulation in cells (IC50: 210 nM).
价 格:¥电议型 号:T16129产 地:中国大陆
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T1597Proadifen hydrochloride;盐酸丙基解痉素U-5446|||RP-5171|||SKF-525A;U-5446|||RP-5171|||SKF-525A|||盐酸丙基解痉素
Proadifen hydrochloride (RP-5171) is an inhibitor of drug metabolism and cytochrome P-450 enzyme system activity.
价 格:¥电议型 号:T1597产 地:中国大陆
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T15650KDM5A-IN-1;KDM5A抑制剂1KDM5A-IN-1
KDM5A-IN-1 is an orally available, potent and selective inhibitor of the pan-histidine lysine demethylase 5 KDM5, inhibiting KDM5A, KDM5B, and KDM5C with IC50 values of 45 nM, 56 nM, and 55 nM, respectively.KDM5A-IN-1 inhibits PC9 H3K4Me3, and may be useful in cancer research.
价 格:¥电议型 号:T15650产 地:中国大陆
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T15424GSK1379725A;化合物GSK1379725AGSK1379725A
GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).
价 格:¥电议型 号:T15424产 地:中国大陆
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T15155Docebenone;化合物 T15155AA 861;AA 861
Docebenone is a selective and orally active inhibitor of 5-LO.
价 格:¥电议型 号:T15155产 地:中国大陆
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T14925Cenisertib;化合物 T14925AS-703569|||R-763;AS-703569|||R-763
Cenisertib is A potent ATP-competitive multi-kinase inhibitor, showing inhibitory effects on the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, FLT3, as well as kinase inhibitors of FER and its homolog. Cenisertib inhibits the growth of tumor mast cells (MCS) by inhibiting the activity of several different molecular targets. Cenisertib also inhibits tumor growth in pancreatic, breast, colon, ovarian and lung cancer and leukemia in xenograft models.
价 格:¥电议型 号:T14925产 地:中国大陆
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T14485Azidoethyl-SS-ethylazide;化合物 T14485Azidoethyl-SS-ethylazide
Azidoethyl-SS-ethylazide is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14485产 地:中国大陆
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T14475Azido-PEG7-amine;化合物 T14475Azido-PEG7-amine
Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14475产 地:中国大陆
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T14465Azido-PEG6-acid;化合物 T14465Azido-PEG6-acid
Azido-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14465产 地:中国大陆
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T14455Azido-PEG5-Ala-Ala-Asn-PAB;化合物 T14455Azido-PEG5-Ala-Ala-Asn-PAB
Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14455产 地:中国大陆
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T14445Azido-PEG4-C2-acid;化合物 T14445Azido-PEG4-C2-acid
Azido-PEG4-C2-acid, a PEG-based PROTAC linker, is utilized in the synthesis of vRucaparib-TP4. It serves as a non-cleavable 4 unit PEG ADC linker for antibody-drug conjugate (ADC) synthesis.
价 格:¥电议型 号:T14445产 地:中国大陆
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T14435Azido-PEG3-Val-Cit-PAB-OH;化合物 T14435Azido-PEG3-Val-Cit-PAB-OH
Azido-PEG3-Val-Cit-PAB-OH is a cleavable three-unit polyethylene glycol antibody-drug conjugate (ADC) linker utilized in ADC synthesis [1].
价 格:¥电议型 号:T14435产 地:中国大陆
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T14425Azido-PEG3-aminoacetic acid-NHS ester;化合物 T14425Azido-PEG3-aminoacetic acid-NHS ester
Azido-PEG3-aminoacetic acid-NHS ester is a PEGylation-based linker for the development of PROTACs[1]. It can be utilized in the synthesis of PROTACs, offering a versatile and efficient approach.
价 格:¥电议型 号:T14425产 地:中国大陆