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T14415Azido-PEG11-amine；化合物 T14415Azido-PEG11-amine
Azido-PEG11-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14415产 地：中国大陆
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T14405Azido-PEG1-C2-acid；化合物 T14405Azido-PEG1-C2-acid
Azido-PEG1-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14405产 地：中国大陆
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T14395Azide-PEG4-Tos；化合物 T14395Azide-PEG4-Tos
Azide-PEG4-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14395产 地：中国大陆
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T14367AZ1495；化合物AZ1495AZ1495
AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL).
价 格：￥电议型 号：T14367产 地：中国大陆
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T14355AVE3085化合物 T14355AVE-3085
AVE-3085 is a potent enhancer of endothelial nitric oxide synthase, and used for cardiovascular disease treatment.
价 格：￥电议型 号：T14355产 地：中国大陆
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T14335ASP6432；化合物 T14335ASP6432
ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively.
价 格：￥电议型 号：T14335产 地：中国大陆
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T14326AS-35；化合物 AS-35AS-35
AS-35 is an orally available, selective and potent leukotrienes antagonist that inhibits LTC4, LTD4 and LTE4-induced ileus contractions.AS-35 has antiallergic properties and inhibits leukotriene synthesis.
价 格：￥电议型 号：T14326产 地：中国大陆
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T14295Antipain；化合物 T14295Antipain
Antipain is a protease inhibitor isolated from Actinomycetes. Antipain inhibits N-methyl-N´-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations[1][2].
价 格：￥电议型 号：T14295产 地：中国大陆
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T14285AN11251；化合物 T14285AN11251
AN11251, a potent oral-active anti-Wolbachia agent, shows promise for treating onchocerciasis and lymphatic filariasis. Demonstrating EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines, it exhibits significant efficacy across different laboratory settings.
价 格：￥电议型 号：T14285产 地：中国大陆
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T14275Aminooxy-PEG4-propargyl；化合物 T14275Aminooxy-PEG4-propargyl
Aminooxy-PEG4-propargyl is a PEG-based PROTAC linker for the synthesis of PROTACs[1].
价 格：￥电议型 号：T14275产 地：中国大陆
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T14265Aminooxy-PEG3-bromide；化合物 T14265Aminooxy-PEG3-bromide
Aminooxy-PEG3-bromide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14265产 地：中国大陆
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T14255Amino-PEG9-Boc；化合物 T14255Amino-PEG9-Boc
Amino-PEG9-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14255产 地：中国大陆
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T14245Amino-PEG5-C2-acid；化合物 T14245Amino-PEG5-C2-acid
Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T14245产 地：中国大陆
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T14235Amino-PEG3-C2-sulfonic acid；化合物 T14235Amino-PEG3-C2-sulfonic acid
Amino-PEG3-C2-sulfonic acid is a PEG-based PROTAC linker utilized for the synthesis of PROTACs [1].
价 格：￥电议型 号：T14235产 地：中国大陆
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T14225Amino-PEG10-OH；化合物 T14225Amino-PEG10-OH
Amino-PEG10-OH is non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T14225产 地：中国大陆
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T14215AMG 837 sodium salt；化合物 T14215AMG 837 sodium salt
AMG 837 sodium salt is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. IC50 value: 13 nM (EC50) [1] Target: GPR40 agonist AMG 837 displayed the expected two-fold increase in potency on GPR4 (EC50 = 13 [±7] nM) compared to the racemic compound and its activity crossed over to the rat and mouse forms of GPR40 (EC50 = 23 and 13 nM, respectively). AMG 837 is a highly potent stimulator of insulin secr
价 格：￥电议型 号：T14215产 地：中国大陆
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T14205AM679；化合物 T14205AM679
AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively. IC50 value: 2.2 nM/0.6 nM/154 nM(FLAP binding/hLA/hWB) [1] AM679 showed an improved CYP inhibition profile (IC50 3A4 = 16.7 lM, 2C9 = 3.7 lM, 2D6 >30 lM), no time dependent inhibition against CYP3A4 (0.003 min-1 vs 0.057 min-1 for troleandomycin control 10 uM) and no CYP3A4 induction. AM679 has an excellent hWB IC50 potency of 154 nM. Target: FLAP in vitro: AM679 showed excell
价 格：￥电议型 号：T14205产 地：中国大陆
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T14195ALS-8112；化合物 T14195ALS-8112
ALS-8112 is a inhibitor of respiratory syncytial virus (RSV) polymerase. The 5´-triphosphate form of ALS-8112 inhibits RSV polymerase (IC50: 0.02 μM).
价 格：￥电议型 号：T14195产 地：中国大陆
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T14165Ald-Ph-amido-PEG4-C2-NHS ester；化合物 T14165Ald-Ph-amido-PEG4-C2-NHS ester
Ald-Ph-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.
价 格：￥电议型 号：T14165产 地：中国大陆
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T14137AG 1295；酪氨酸磷酸化抑制剂AG1295AG 1295
AG 1295, a selective inhibitor of platelet-derived growth factor receptor (PDGFR) tyrosine-kinase, effectively halts PDGFR autophosphorylation without impacting the autophosphorylation of the EGF receptor[1][2][3][4].
价 格：￥电议型 号：T14137产 地：中国大陆
