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T36580Glucagon Receptor Antagonist Inactive Control;Glucagon Receptor Antagonist Inactive ControlGlucagon
Glucagon Receptor Antagonist Inactive Control is a Glucagon receptor antagonist that can be used in related research in the field of life sciences. Its product number is T36580 and CAS number is 362482-00-6.
价 格:¥电议型 号:T36580产 地:中国大陆
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T36546Prostaglandin I3 (sodium salt);Prostaglandin I3 (sodium salt)Prostaglandin I3 (sodium salt);Prostagl
PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.
价 格:¥电议型 号:T36546产 地:中国大陆
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T36545Prostaglandin D2 methyl ester;Prostaglandin D2 methyl esterProstaglandin D2 methyl ester;Prostagland
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation. Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2. It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.
价 格:¥电议型 号:T36545产 地:中国大陆
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T36544Prostaglandin D1;Prostaglandin D1Prostaglandin D1;Prostaglandin D1
Prostaglandin D1 is a prostaglandin that has contraction and relaxation effects on isolated human arteries and can inhibit ADP-induced platelet aggregation (IC50=320 ng/ml). Prostaglandin D1 can be used in metabolic studies.
价 格:¥电议型 号:T36544产 地:中国大陆
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T36543Prostaglandin B2;Prostaglandin B2PGB2;PGB2
Prostaglandin B2 (PGB2) is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base. It has weak agonist activity on TP receptors and can increase pulmonary blood pressure in the rabbit at relatively high doses (5 ug/kg). [1]
价 格:¥电议型 号:T36543产 地:中国大陆
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T3645511β-Prostaglandin F2α;11β-Prostaglandin F2α11β-Prostaglandin F2α;11β-Prostaglandin F2α
11β-Prostaglandin F2α is a bioactive metabolite catalyzed by AKR1C3 that stimulates prostaglandin F receptors and induces slug expression in breast cancer. 11β-Prostaglandin F2α is also an endogenous metabolite present in urine.
价 格:¥电议型 号:T36455产 地:中国大陆
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T36255dTAGV-1-NEGdTAGV-1-NEGdTAGV 1 NEG|||dTAGV1NEG
Negative control for dTAGV-1.
价 格:¥电议型 号:T36255产 地:中国大陆
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T36254dTAGV-1 hydrochloride;dTAGV-1 hydrochloridedTAGV-1 hydrochloride
Hydrochloride salt of dTAGV-1. Suitable for use in vivo. Following ip administration of 10 mg/kg in mice: T = 4.43 h; Cmax = 2123 ng mL-1; AUCinf = 18517 hr*ng mL-1 and CL = 9.05 mL min-1 kg-1 Negative control dTAGV-1-NEG also available. Important: It is recommended that DMSO stock solutions of this compound are made and used on the same day and are not subjected to freeze/thaw.
价 格:¥电议型 号:T36254产 地:中国大陆
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T36253dTAGV-1;dTAGV-1dTAGV-1
Degrader targeting mutant FKBP12F36V fusion proteins. Comprises a ligand selective for F36V single-point mutated FKBP12, a linker and a von Hippel-Lindau (VHL)-binding ligand. Induces potent and selective degradation of FKBP12F36V fusion proteins in vitro and in vivo. Selectively degrades FKBP12F36V-EWS/FLI fusion proteins and inhibits cell proliferation in FKBP12F36V-EWS/FLI-expressing Ewing sarcoma cells. Hydrochloride salt available; suitable for in vivo use. Negative control dTAGV-1-NEG al
价 格:¥电议型 号:T36253产 地:中国大陆
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T362396β-Prostaglandin I1;6β-Prostaglandin I16β-Prostaglandin I1;6β-Prostaglandin I1
6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 μM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.
价 格:¥电议型 号:T36239产 地:中国大陆
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T362386α-Prostaglandin I1;6α-Prostaglandin I16α-Prostaglandin I1;6α-Prostaglandin I1
6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting the response. 6α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI
价 格:¥电议型 号:T36238产 地:中国大陆
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T362191a,1b-dihomo Prostaglandin E1;1a,1b-dihomo Prostaglandin E11a,1b-dihomo Prostaglandin E1;1a,1b-dihom
1a,1b-dihomo Prostaglandin E1 is a class of prostaglandin compounds.
价 格:¥电议型 号:T36219产 地:中国大陆
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T3621416,16-dimethyl Prostaglandin E1;16,16-dimethyl Prostaglandin E116,16-dimethyl Prostaglandin E1;16,16
16,16-dimethyl Prostaglandin E1 is a PGE1 (T1626) analog that induces bronchoconstriction and vascular smooth muscle contraction and inhibits indomethacin-induced cell elongation.
价 格:¥电议型 号:T36214产 地:中国大陆
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T3621316,16-dimethyl Prostaglandin D2;16,16-dimethyl Prostaglandin D216,16-dimethyl Prostaglandin D2;16,16
16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2. It enhances ADP-induced human platelet aggregation and increases systemic blood pressure in rats.
价 格:¥电议型 号:T36213产 地:中国大陆
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T3620915-keto Prostaglandin A1;15-keto Prostaglandin A115-keto Prostaglandin A1;15-keto Prostaglandin A1
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 in pig lung, trachea, aorta, and pulmonary artery tissue preparations. 15-keto PGA1, given at a concentration of 6 μM, causes vasoconstriction of rabbit lung that is comparable to that induced by angiotensin II.
价 格:¥电议型 号:T36209产 地:中国大陆
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T361688-iso-16-cyclohexyl-tetranor Prostaglandin E2;8-iso-16-cyclohexyl-tetranor Prostaglandin E28-iso-16-
8-iso Prostaglandin E2 (8-iso PGE2) is one of several isoprostanes produced from polyunsaturated fatty acids during lipid peroxidation. 8-iso-16-cyclohexyl-tetranor PGE2 is a synthetic analog of 8-iso PGE2. There are no published studies on the pharmacological properties of 8-iso-16-cyclohexyl-tetranor PGE2.
价 格:¥电议型 号:T36168产 地:中国大陆
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T361678-iso-15-keto Prostaglandin F2β;8-iso-15-keto Prostaglandin F2β8-iso-15-keto Prostaglandin F2β;8-iso
8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α of non-enzymatic origin. It is one of 64 possible isomers of PGF2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2β exhibits very weak contraction of human umbilical vein artery and does not promote aggregation of human whole blood. However, 8-iso PGF2β moderately contracts both the canine and porcine pulmonary vein, although the effect is much weaker than that exhibited by other isoprostanes such as 8
价 格:¥电议型 号:T36167产 地:中国大陆
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T361668-iso-15-keto Prostaglandin F2α;8-iso-15-keto Prostaglandin F2α8-iso-15-keto Prostaglandin F2α;8-iso
8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2α is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-iso PGF2α is infused into rabbits. Early in the in
价 格:¥电议型 号:T36166产 地:中国大陆
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T361658-iso-13,14-dihydro-15-keto Prostaglandin F2α;8-iso-13,14-dihydro-15-keto Prostaglandin F2α8-iso-13,
8-iso-13,14-dihydro-15-keto Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits, monkeys and humans. 8-iso PGF2α is a PG-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-isoprostane is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-isoprostane is infused into ra
价 格:¥电议型 号:T36165产 地:中国大陆