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T40251dTAGV-1 TFA;dTAGV-1 TFAdTAGV-1 TFA
dTAGV-1 TFA is a highly effective and specific compound that targets mutant FKBP12 F36V fusion proteins for degradation. It possesses potent activity in inducing the degradation of the FKBP12 F36V -Nluc protein in living organisms.
价 格:¥电议型 号:T40251产 地:中国大陆
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T40176MrgprX2 antagonist-5MrgprX2 antagonist-5MrgprX2 antagonist-5
MrgprX2 antagonist-5, which acts as a potent antagonist of MrgprX2. It exhibits the ability to effectively inhibit the activity of MrgprX2, making it an ideal candidate for research related to inflammatory skin disorders.
价 格:¥电议型 号:T40176产 地:中国大陆
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T398705-HT7R antagonist 1 free base5-HT7R antagonist 1 free base5-HT7R antagonist 1 free base
5-HT7R antagonist 1 (free base) is a G protein-biased antagonist for the 5-HT 7 R receptor, with a dissociation constant (K i) of 6.5 nM.
价 格:¥电议型 号:T39870产 地:中国大陆
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T39798S1P2 antagonist 1;S1P2 antagonist 1S1P2 antagonist 1
S1P2 antagonist 1 is an orally bioavailable S1P2 antagonist against fibrotic diseases.
价 格:¥电议型 号:T39798产 地:中国大陆
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T39762AHR antagonist 5 free base;化合物AHR antagonist 5 free baseAHR antagonist 5 free base
AHR antagonist 5 free base is an orally active antagonist of AHR with IC50s of ~35-150 nM in human and rodent cell lines.
价 格:¥电议型 号:T39762产 地:中国大陆
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T39742CXCR4 antagonist 2;CXCR4 antagonist 2CXCR4 antagonist 2
CXCR4 antagonist 2 is a CXCR4 antagonist with an IC 50 value of 47 nM.
价 格:¥电议型 号:T39742产 地:中国大陆
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T39662CCR4 antagonist 3 hydrochloride;CCR4 antagonist 3 hydrochlorideCCR4 antagonist 3 hydrochloride
CCR4 antagonist 3 hydrochloride is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4 antagonist 3 has antitumor activity.
价 格:¥电议型 号:T39662产 地:中国大陆
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T39661CCR4 antagonist 3CCR4 antagonist 3CCR4 antagonist 3
CCR4 antagonist 3 is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4 antagonist 3 has antitumor activity.
价 格:¥电议型 号:T39661产 地:中国大陆
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T39278L-Pentaguluronic acid;L-古罗糖醛酸五糖L-Pentaguluronic acid
L-Pentaguluronic acid, a linear polysaccharide copolymer, consists predominantly of four units of L-guluronic acid (G).
价 格:¥电议型 号:T39278产 地:中国大陆
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T39164MC-betaglucuronide-MMAE-1;MC-betaglucuronide-MMAE-1MC-betaglucuronide-MMAE-1
MC-betaglucuronide-MMAE-1 is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), employing MMAE (a tubulin polymerization inhibitor) connected through the cleavable ADC linker MC-betaglucuronide.
价 格:¥电议型 号:T39164产 地:中国大陆
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T39078CXCR7 antagonist-1;CXCR7拮抗剂1CXCR7 antagonist-1;CXCR7 antagonist-1
CXCR7 antagonist-1 is a specific antagonist of the binding of the SDF-1 chemokine or I-TAC to the chemokine receptor CXCR7. CXCR7 antagonist-1 prevents tumor cell proliferation and tumor formation and can be used in studies about inflammatory diseases.
价 格:¥电议型 号:T39078产 地:中国大陆
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T38947Udonitrectag;UdonitrectagREC 0559;REC 0559
Udonitrectag (REC 0559) is a low molecular weight compound developed to emulate the behavior of NGF, with the objective of tackling the challenge of maintaining NGF stability.
价 格:¥电议型 号:T38947产 地:中国大陆
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T38910mGluR2 antagonist 1;mGluR2 antagonist 1mGluR2 antagonist 1
mGluR2 antagonist 1 is a potent and selective class of negative allosteric modulator targeting the metabotropic glutamate receptor 2 (mGluR2) with high oral bioavailability. It displays a remarkable affinity for mGluR2, with an IC50 value of 9 nM. Furthermore, it exhibits excellent permeability across the blood-brain barrier, making it a promising candidate for central nervous system-related studies or therapies.
价 格:¥电议型 号:T38910产 地:中国大陆
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T38634Histamine H4 receptor antagonist-1;Histamine H4 receptor antagonist-1Histamine H4 receptor antagonis
Histamine H4 receptor antagonist-1 is a potent antagonist of the histamine H4 receptor.
价 格:¥电议型 号:T38634产 地:中国大陆
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T38622Bcl-xL antagonist 2;Bcl-xL拮抗剂2Bcl-xL antagonist 2
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic leukemia and non-Hodgkin’s lymphoma.
价 格:¥电议型 号:T38622产 地:中国大陆
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T38595EP4 receptor antagonist 3EP4 receptor antagonist 3EP4 receptor antagonist 3
EP4 receptor antagonist 3 is a highly potent and specific inhibitor of the EP4 receptor. It is intended for research purposes in studying EP4 receptor-mediated diseases such as acute and chronic pain, osteoarthritis, rheumatoid arthritis, and cancer.
价 格:¥电议型 号:T38595产 地:中国大陆
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T38389Prostaglandin D2 Ethanolamide;Prostaglandin D2 EthanolamideProstaglandin D2 Ethanolamide;Prostagland
Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase. PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor. It increases the frequency of minia
价 格:¥电议型 号:T38389产 地:中国大陆
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T3834211-deoxy Prostaglandin E2;11-deoxy Prostaglandin E211-deoxy Prostaglandin E2;11-deoxy Prostaglandin
11-deoxy Prostaglandin E2 (11-deoxy PGE2) is a stable, synthetic analog of PGE2 . In contrast to PGE2 which has bronchodilation effects, 11-deoxy PGE2 is a powerful bronchoconstrictor and contracts human respiratory tract smooth muscle with potencies ranging from 5 to 30 times higher than PGF2α .
价 格:¥电议型 号:T38342产 地:中国大陆
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T38226TSHR antagonist S37b;TSHR antagonist S37bTSHR antagonist S37b
TSHR antagonist S37b, the less potent enantiomer of TSHR antagonist S37a, exhibits minimal efficacy in inhibiting the thyrotropin receptor (TSHR). It is utilized in thyroid function research[1].
价 格:¥电议型 号:T38226产 地:中国大陆
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T38198Prostaglandin F2α methyl ester;Prostaglandin F2α methyl esterProstaglandin F2α methyl ester
Prostaglandin F2α methyl ester is a highly lipid-soluble PGF2α analog used to maintain low intraocular pressure.
价 格:¥电议型 号:T38198产 地:中国大陆