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T60840EP4 receptor antagonist 4;化合物 EP4 receptor antagonist 4EP4 receptor antagonist 4
EP4 receptor antagonist 4 is an agonist of EP4 receptor (human pEC 50 = 6.3) [1].
价 格:¥电议型 号:T60840产 地:中国大陆
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T60811CXCR4 antagonist 7;化合物 CXCR4 antagonist 7CXCR4 antagonist 7
CXCR4 antagonist 7 (Compound PARA-B) is able to be used in the HIV infection, inflammatory diseases, cancer, and WHIM syndrome research which is a antagonist of CXCR4 (IC 50 = 9.3 nM) [1].
价 格:¥电议型 号:T60811产 地:中国大陆
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T60792NMDA receptor antagonist-3;化合物 NMDA receptor antagonist-3NMDA receptor antagonist-3
NMDA receptor antagonist-3 is a NMDA receptor antagonist with a significan recovery rate (40.0%, at 100 μM) and safe toxicological characteristics in SH-SY5Y and human adipose mesenchymal stem cells.
价 格:¥电议型 号:T60792产 地:中国大陆
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T607905-HT7R antagonist 1;化合物 5-HT7R antagonist 15-HT7R antagonist 1
5-HT7R antagonist 1 is a G protein-biased antagonist with Ki of 6.5 nM for 5-HT 7R.
价 格:¥电议型 号:T60790产 地:中国大陆
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T60756NLRP3 antagonist 1;化合物 NLRP3 antagonist 1NLRP3 antagonist 1
NLRP3 antagonist 1 shows potential for the cancer research that is a potent NLRP3 antagonist. NLRP3 is involved in the body´s intrinsic immunity against stress injury and pathogenic infections that is mainly expressed in macrophages and neutrophils [1].
价 格:¥电议型 号:T60756产 地:中国大陆
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T60732A2A/A1 AR antagonist-1;化合物 A2A/A1?AR antagonist-1A2A/A1 AR antagonist-1
A2A/A1 AR antagonist-1 (compound 1a) has the potential for ischemic stroke research which is potent A 2A /A 1 AR dual antagonist with Ki s of 5.58 and 24.2 nM, respectively [1].
价 格:¥电议型 号:T60732产 地:中国大陆
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T60719AR antagonist 3;化合物 AR antagonist 3AR antagonist 3
When administered intratumorally, AR antagonist 3 shows effective inhibition on the growth of tumor. AR antagonist 3 is a potent and selective antagonist of androgen receptor (AR) with an IC 50 of 0.47 μM. AR antagonist 3 dose-dependently decrease the FRET signal with an IC50 of 18.05 μM [1].
价 格:¥电议型 号:T60719产 地:中国大陆
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T60696CXCR2 antagonist 8;化合物 CXCR2 antagonist 8CXCR2 antagonist 8
CXCR2 antagonist 8 is a potent and selective antagonist of CXCR2 that can be used for the researching of insulin resistance [1].
价 格:¥电议型 号:T60696产 地:中国大陆
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T60687A1AR antagonist 1;化合物 A1AR?antagonist 1A1AR antagonist 1
A1AR antagonist 1 (compound 18g) is a potent antagonist of A1 adenosine receptor (AR). A1AR antagonist 1 has Ki values of 2.08, 6.91, and 31.2 nM for hA1, hA2A and hA2B, respectively [1].
价 格:¥电议型 号:T60687产 地:中国大陆
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T60615A1AR antagonist 6;化合物 A1AR antagonist 6A1AR antagonist 6
A1AR antagonist 6 (compound 15) is a potent and selective antagonist of A1 adenosine receptor(A1AR) with a pKi of 7.13 and a pIC 50 of 6.38[1].
价 格:¥电议型 号:T60615产 地:中国大陆
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T60591A2AAR antagonist 1;化合物 A2AAR antagonist 1A2AAR antagonist 1
A2AAR antagonist 1 (compound 21a) is an antagonist of A2AAR (adenosine A2A receptor) that shows high ligand efficiency with a Ki value of 20 nM. A2AAR antagonist 1 can be used in neurodegenerative disease research [1].
价 格:¥电议型 号:T60591产 地:中国大陆
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T60580A1AR antagonist 2;化合物 A1AR antagonist 2A1AR antagonist 2
A1AR antagonist 2 (compound 18h) is a potent antagonist of the A1 adenosine receptor (AR). A1AR antagonist 2 has Ki values of 1.49, 10.2, and 50.1 nM for hA 1, hA 2A, and hA 2B, respectively [1].
价 格:¥电议型 号:T60580产 地:中国大陆
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T60336CCR4 antagonist 3-1;CCR4拮抗剂3-1CCR4 antagonist 3-1
CCR4 antagonist 3-1 is a less active chemokine receptor 4 (CCR4) antagonist that inhibits [125I]TARC (thymus and activation-regulated chemokine) with an IC50 value of 1.7 μM. CCR4 antagonist 3-1 inhibits the binding of radiolabeled [125I]TARC and macrophage-derived chemokine ( MDC) to CEM cell surface and inhibits TARC-mediated CEM cell migration in vitro with an IC50 value of 6.4 μM. CCR4 antagonist 3 inhibited the binding of radiolabeled [125I]TARC and macrophage-derived chemokine (MDC) to the
价 格:¥电议型 号:T60336产 地:中国大陆
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T60306NMDA receptor antagonist 4;化合物 NMDA receptor antagonist 4NMDA receptor antagonist 4
NMDA receptor antagonist 4 (IIc) is an uncompetitive, voltage-dependent, orally active NMDAR blocker, with an IC 50 of 1.93 μM. NMDA receptor antagonist 4 shows a positive predicted blood-brain-barrier (BBB) permeability, and can be used in Alzheimer´s disease research[1].
价 格:¥电议型 号:T60306产 地:中国大陆
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T60249RhlR antagonist 1;化合物 RhlR antagonist 1RhlR antagonist 1
RhlR antagonist 1 is a highly effective antagonist of the RhlR protein, showing an IC50 value of 26 μM. It exhibits selective antagonistic activity against RhlR, with minimal effect on LasR and PqsR. RhlR antagonist 1 strongly inhibits biofilm formation in both static and dynamic environments and reduces the production of virulence factors, such as rhamnolipid and pyocyanin, in P. aeruginosa. These characteristics make RhlR antagonist 1 a valuable tool for the development of molecules that modul
价 格:¥电议型 号:T60249产 地:中国大陆
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T60145CCR6 antagonist 1;CCR6拮抗剂1CCR6 antagonist 1
CCR6 antagonist 1, a chemical compound acting as a CCR6 antagonist, effectively inhibits the CCL20/CCR6 axis. Its utility lies in research focused on autoimmune-mediated inflammatory diseases, including inflammatory bowel diseases (IBDs).
价 格:¥电议型 号:T60145产 地:中国大陆
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T5962TRPM8 antagonist WS-3;N-乙基-5-甲基-2-(1-甲基乙基)环己甲酰胺Cyclohexanecarboxamide|||N-Ethyl-p-menthane-3-carboxa
TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 μM).
价 格:¥电议型 号:T5962产 地:中国大陆
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T5903Sitagliptin Intermediate 2;化合物 T5903Sitagliptin Intermediate 2
Sitagliptin Intermediate 2 is a useful organic compound that has been used in life science related research.
价 格:¥电议型 号:T5903产 地:中国大陆
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T5829H4 Receptor antagonist 1;化合物H4 Receptor antagonist 1H4 Receptor antagonist 1
H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.
价 格:¥电议型 号:T5829产 地:中国大陆
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T5698TRPM8 antagonist 2;化合物TRPM8 antagonist 2TRPM8 antagonist 2
TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.
价 格:¥电议型 号:T5698产 地:中国大陆