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已选条件
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T17376Ald-Ph-PEG24-TFP ester;化合物 T17376Ald-Ph-PEG24-TFP ester
Ald-Ph-PEG24-TFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17376产 地:中国大陆
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T17366Ald-CH2-PEG10-Boc;化合物 T17366Ald-CH2-PEG10-Boc
Ald-CH2-PEG10-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17366产 地:中国大陆
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T17356Acid-propionylamino-Val-Cit-OH;化合物 T17356Acid-propionylamino-Val-Cit-OH
Acid-propionylamino-Val-Cit-OH is a cleavable linker commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17356产 地:中国大陆
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T17190U18666A;化合物U18666AU18666A
U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.
价 格:¥电议型 号:T17190产 地:中国大陆
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T17096Tilapertin;化合物 T17096AMG747;AMG747
Tilapertin is an oral glycine transporter type-1 inhibitor.
价 格:¥电议型 号:T17096产 地:中国大陆
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T16386Ombrabulin hydrochloride化合物 T16386AVE8062 (hydrochloride)|||AC7700 (hydrochloride)
Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and has antivascular effects. Ombrabulin is a tubulin polymerizing inhibitor, a member of the combretastatin A-4 compound class, which is a water-soluble tubulin depolymerizing tumor vascularizing compound.
价 格:¥电议型 号:T16386产 地:中国大陆
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T15666KP136;化合物 KP136AL136;AL136
KP136 (AL136) is an orally active anti-allergic compound that inhibits histamine release and is used in studies of asthma and allergic edema.
价 格:¥电议型 号:T15666产 地:中国大陆
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T15636K-252a;化合物 T15636Antibiotic K 252a|||Antibiotic SF 2370|||SF2370;Antibiotic K 252a|||Antibiotic SF 2
K-252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi. K-252a inhibits protein kinase (IC50: 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively).
价 格:¥电议型 号:T15636产 地:中国大陆
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T14589Biotin-PEG3-acid化合物Biotin-PEG3-acid18-[(3AS,4S,6AR)-六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-基]-14-氧代-4,7,10-三氧杂-13
Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
价 格:¥电议型 号:T14589产 地:中国大陆
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T14486Azidoethyl-SS-PEG2-Boc;化合物 T14486Azidoethyl-SS-PEG2-Boc
Azidoethyl-SS-PEG2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14486产 地:中国大陆
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T14476Azido-PEG8-Boc;化合物 T14476Azido-PEG8-Boc
Azido-PEG8-Boc is a polyethylene glycol (PEG) and alkyl/ether-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T14476产 地:中国大陆
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T14466Azido-PEG6-alcohol;化合物 T14466Azido-PEG6-alcohol
Azido-PEG6-alcohol is a polyethylene glycol (PEG)-based PROTAC linker utilized in PROTAC synthesis[1]. It also functions as a non-cleavable PEG linker consisting of six units, specifically employed in the synthesis of antibody-drug conjugates (ADCs)[2].
价 格:¥电议型 号:T14466产 地:中国大陆
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T14456Azido-PEG5-alcohol;化合物 T14456Azido-PEG5-alcohol
Azido-PEG5-alcohol, a non-cleavable 5 unit polyethylene glycol (PEG) ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, it serves as a PEG-based PROTAC linker for the synthesis of PROTACs[2].
价 格:¥电议型 号:T14456产 地:中国大陆
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T14436Azido-PEG3-Val-Cit-PAB-PNP;化合物 T14436Azido PEG3 Val Cit PAB PNP|||Azido-PEG3-Val-Cit-PAB-PNP|||Azido
Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3 unit PEG ADC linker employed for synthesizing antibody-drug conjugates (ADCs)[1]. It also serves as a PEG-based PROTAC linker for the synthesis of PROTACs[2].
价 格:¥电议型 号:T14436产 地:中国大陆
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T14426Azido-PEG3-C-Boc;化合物 T14426Azido-PEG3-C-Boc
Azido-PEG3-C-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14426产 地:中国大陆
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T14406Azido-PEG1-C2-methylamine;化合物 T14406Azido-PEG1-C2-methylamine
Azido-PEG1-C2-methylamine is a PEG-conjugated linker employed in the synthesis of PROTACs[1].
价 格:¥电议型 号:T14406产 地:中国大陆
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T14396Azide-PEG5-Boc;化合物 T14396Azide-PEG5-Boc
Azide-PEG5-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14396产 地:中国大陆
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T14365AZ PFKFB3 26;化合物AZ PFKFB3 26AZ PFKFB3 26
AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 μM, respectively.
价 格:¥电议型 号:T14365产 地:中国大陆
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T14360AX-15836;化合物AX-15836AX-15836
AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).
价 格:¥电议型 号:T14360产 地:中国大陆
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T14356AVE-8134;化合物 T14356AVE-8134
AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.
价 格:¥电议型 号:T14356产 地:中国大陆