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T10625L(Rac)-IBT6A hydrochloride (1412418-47-3 free base);化合物 T10625L(Rac)-IBT6A hydrochloride;(Rac)-IBT6A
(Rac)-IBT6A hydrochloride is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib. IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM).
价 格:¥电议型 号:T10625L产 地:中国大陆
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T10625IBT6A依鲁替尼中间体依鲁替尼中间体
IBT6A is an impurity of Ibrutinib. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM). IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.
价 格:¥电议型 号:T10625产 地:中国大陆
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T10426AZ12601011;化合物 T10426AZ12601011
AZ12601011 is a highly potent and selective inhibitor of the TGFBR1 kinase, administered orally. It displays an IC50 of 18 nM and a Kd of 2.9 nM. By selectively targeting ALK4, TGFBR1, and ALK7, AZ12601011 effectively inhibits the phosphorylation of SMAD2. Additionally, it has been shown to hinder the growth and metastasis of mammary tumors [1].
价 格:¥电议型 号:T10426产 地:中国大陆
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T10416Autotaxin-IN-4;化合物 T10416Autotaxin-IN-4
Autotaxin-IN-4 is an Autotaxin inhibitor. It has the potential to treat idiopathic pulmonary fibrosis.
价 格:¥电议型 号:T10416产 地:中国大陆
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T10396ATM Inhibitor-1;化合物 T10396ATM Inhibitor-1
ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) anti-tumor activity. It shows weak activity against mTOR (IC50, 21 μM), DNAPK (IC50, 2.8 μM), PI3Kα (IC50, 3.8 μM), PI3Kβ (IC50, 10.3 μM), PI3Kγ (IC50, 3 μM) and PI3Kδ (IC50, 0.73 μM).
价 格:¥电议型 号:T10396产 地:中国大陆
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T10386Asp-AMS;化合物 T10386Asp-AMS
Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.
价 格:¥电议型 号:T10386产 地:中国大陆
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T10346Apelin agonist 1;化合物 T10346Apelin agonist 1
Apelin agonist 1 is an oral selective apelin agonist AM-2995, an agonist of the APJ (APLNR, angiotensin receptor like-1) receptor. It may be used in the treatment of cardiovascular conditions.
价 格:¥电议型 号:T10346产 地:中国大陆
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T10326Aniline-MPB-amino-C3-PBD;化合物 T10326Aniline-MPB-amino-C3-PBD
Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised of the non-alkylating group. It is a sequence-selective DNA minor-groove binding agent.
价 格:¥电议型 号:T10326产 地:中国大陆
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T10306Amoxicillin D4;化合物 T10306Amoxycillin D4;Amoxycillin D4
Amoxicillin D4 (Amoxycillin D4) is a deuterium-labeled Amoxicillin. Amoxicillin is an antibiotic with broad-spectrum antimicrobial activity.
价 格:¥电议型 号:T10306产 地:中国大陆
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T10296Mavorixafor trihydrochloride;化合物 T10296AMD-070 trihydrochloride;AMD-070 trihydrochloride
Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (IC50s: 1 and 9 nM).
价 格:¥电议型 号:T10296产 地:中国大陆
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T10286ALK/ROS1-IN-1;化合物 T10286ALK/ROS1-IN-1
ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme).
价 格:¥电议型 号:T10286产 地:中国大陆
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T10266Agomelatine-d6;化合物 T10266Agomelatine D6|||S-20098 D6;Agomelatine D6|||S-20098 D6
Agomelatine D6 (S-20098 D6) is a deuterium-labeled Agomelatine. Agomelatine is a specific agonist of MT1 and MT2 receptors.
价 格:¥电议型 号:T10266产 地:中国大陆
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T10261AGN 196996;化合物AGN 196996AGN 196996
AGN 196996 is a potent and selective inhibitor of RARα (Ki: 2 nM).AGN 196996 has very low affinity for RARβ and RARγ, with a Ki of 1087 nM and 8523 nM, respectively.
价 格:¥电议型 号:T10261产 地:中国大陆
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T10259AGI-25696;化合物AGI-25696AGI-25696
AGI-25696 is an inhibitor of methionine adenosyltransferase 2A (MATA2). AGI-25696 blocks the growth of MTAP-deleted tumors in vivo and can be used for studies about the treatment of cancer.
价 格:¥电议型 号:T10259产 地:中国大陆
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T10236ACHN-975 TFA;化合物 T10236ACHN-975 TFA
ACHN-975 TFA is a selective LpxC inhibitor with a subnanomolar inhibitory. It is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL).
价 格:¥电议型 号:T10236产 地:中国大陆
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T10226Sofiniclin;化合物 T10226ABT 894;ABT 894
Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).
价 格:¥电议型 号:T10226产 地:中国大陆