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T14306Apimostinel;化合物 T14306AGN-241660|||NRX-1074;AGN-241660|||NRX-1074
Apimostinel (NRX-1074; AGN-241660) is a partial agonist of NMDA receptor.
价 格:¥电议型 号:T14306产 地:中国大陆
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T14296Antitumor agent-3;化合物 T14296Antitumor agent-3
Antitumor agent-3 is a potent compound. It comprises a new imidazopyridine having excellent antitumor activity as an active ingredient.
价 格:¥电议型 号:T14296产 地:中国大陆
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T14286ANB-NOS;化合物 T14286ANB-NOS
ANB-NOS is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14286产 地:中国大陆
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T14276Aminooxy-PEG5-azide;化合物 T14276Aminooxy-PEG5-azide
Aminooxy-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
价 格:¥电议型 号:T14276产 地:中国大陆
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T14266Aminooxy-PEG3-C2-Boc;化合物 T14266Aminooxy-PEG3-C2-Boc
Aminooxy-PEG3-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14266产 地:中国大陆
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T14256Amino-Tri-(carboxyethoxymethyl)-methane;化合物 T14256Amino-Tri-(carboxyethoxymethyl)-methane
Amino-Tri-(carboxyethoxymethyl)-methane, an ADC linker and PROTAC linker, is a cleavable PEG compound utilized for the synthesis of antibody-drug conjugates (ADCs)[1] and PEG-based PROTACs[2].
价 格:¥电议型 号:T14256产 地:中国大陆
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T14246Amino-PEG5-CH2COOH;化合物 T14246Amino-PEG5-CH2COOH
Amino-PEG5-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14246产 地:中国大陆
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T14236Amino-PEG3-CH2COOH;化合物 T14236Amino PEG3 CH2COOH|||AminoPEG3CH2COOH|||Amino-PEG-3-CH2COOH|||Amino-PEG
Amino-PEG3-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14236产 地:中国大陆
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T14216AMG 837;化合物 T14216AMG 837
AMG 837 is a partial GPR40 agonist with an EC50 value of 13 nM, showcasing 85% of the maximal activity displayed by DHA in standard assay conditions, indicating its high potency and selectivity in vitro. This compound excels as a GPR40 agonist with a notable pharmacokinetic profile, effectively stimulating insulin secretion in a glucose-dependent manner in rodents and demonstrating potent insulin secretion stimulation in MIN6 cells, with efficacy comparable to that observed in aequorin Ca2+-flux
价 格:¥电议型 号:T14216产 地:中国大陆
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T14166Ald-Ph-PEG2-NH-Boc;化合物 T14166Ald-Ph-PEG2-NH-Boc
Ald-Ph-PEG2-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14166产 地:中国大陆
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T14156Ald-CH2-PEG3-azide;化合物 T14156Ald-CH2-PEG3-azide
Ald-CH2-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14156产 地:中国大陆
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T14154Alclometasone;化合物 T141547a-?Chloro-?16a-?methyl prednisolone;7a-?Chloro-?16a-?methyl prednisolone
Alclometasone (7a-Chloro-16a-methyl prednisolone), a glucocorticoid, inhibits leukocytes from releasing pro-inflammatory mediators. It is effective in treating corticosteroid-responsive dermatoses such as atopic dermatitis, psoriasis, allergic dermatitis, and eczema [1].
价 格:¥电议型 号:T14154产 地:中国大陆
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T14136AG-024322;化合物 T14136AG-024322
AG-024322 is a potent ATP-competitive inhibitor of pan-CDK against cell cycle kinases CDK1, CDK2, and CDK4(Ki values in the 1-3 nM range)
价 格:¥电议型 号:T14136产 地:中国大陆
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T14126ADDA 5 hydrochloride;化合物 T14126ADDA 5 hydrochloride
ADDA 5 hydrochloride is a partial non-competitive inhibitor of cytochrome c oxidase (CcO). For purified CcO from human glioma and bovine heart, the IC50s are 18.93 μM and 31.82 μM , respectively.
价 格:¥电议型 号:T14126产 地:中国大陆
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T14106Acid-PEG4-mono-methyl ester;化合物 T14106Acid-PEG4-mono-methyl ester
Acid-PEG4-mono-methyl ester, a PEG- and Alkyl/ether-based PROTAC linker, can be employed for PROTAC synthesis[1].
价 格:¥电议型 号:T14106产 地:中国大陆
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T14096Acid-C2-PEG3-NHS ester;化合物 T14096Acid-C2-PEG3-NHS ester
Acid-C2-PEG3-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14096产 地:中国大陆
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T14089AC-261066;化合物AC-261066AC 261066;AC 261066
AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.
价 格:¥电议型 号:T14089产 地:中国大陆
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T14086ABT-072;化合物 T14086ABT-072
ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.
价 格:¥电议型 号:T14086产 地:中国大陆
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T13556Ascr#3;化合物 T13556Ascr#3
Ascr#3, an ascaroside isolated from Caenorhabditis elegans, acts as a potent male attractant, and also promotes dauer formation combined with ascr#2 at low concentration.
价 格:¥电议型 号:T13556产 地:中国大陆
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T13546AM12;化合物 T13546AM12
AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).
价 格:¥电议型 号:T13546产 地:中国大陆