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  • T64347ALDH1A3-IN-3；化合物ALDH1A3-IN-3ALDH1A3-IN-3

    ALDH1A3-IN-3 (compound 16), a powerful ALDH1A3 inhibitor with an IC50 of 0.26 μM, serves as an effective ALDH3A1 substrate. It is utilized in prostate cancer research.

    价 格：￥电议型 号：T64347产 地：中国大陆

  • T64265JAK1/TYK2-IN-3；化合物 JAK1/TYK2-IN-3JAK1/TYK2-IN-3

    JAK1/TYK2-IN-3 is a selective, potent, orally active dual inhibitor of TYK2 (IC50: 6 nM) and JAK1 (IC50: 37 nM).JAK1/TYK2-IN-3 selectively acts on both JAK2 and JAK3 with IC50 values of 140 nM and 362 nM.JAK1/TYK2 -IN-3 regulates the expression of TYK2/JAK1-related genes and the formation of Th1, Th2 and Th17 cells to exert its anti-inflammatory activity.

    价 格：￥电议型 号：T64265产 地：中国大陆

  • T64230α-Glucosidase-IN-3；化合物 α-Glucosidase-IN-3α-Glucosidase-IN-3

    α-Glucosidase-IN-3 is an oleanolic acid oxime ester derivative targeting α-glucosidase and α-amylase with an IC50 value of 0.35 μM for α-glucosidase.

    价 格：￥电议型 号：T64230产 地：中国大陆

  • T64228ALDH1A1-IN-3；化合物 ALDH1A1-IN-3ALDH1A1-IN-3

    ALDH1A1-IN-3 is a good and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50: μM).ALDH1A1-IN-3 is effective in improving glucose consumption in HepG2 cells.ALDH1A1-IN-3 can be used for studies to improve glucose metabolism.

    价 格：￥电议型 号：T64228产 地：中国大陆

  • T64213Cap-dependent endonuclease-IN-3；化合物 Cap-dependent endonuclease-IN-3Cap-dependent endonuclease-IN-3

    Cap-dependent endonuclease-IN-3 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). Cap-dependent endonuclease-IN-3 has shown potential for the investigation of influenza A and B infections.

    价 格：￥电议型 号：T64213产 地：中国大陆

  • T64199PI3KC2α-IN-3；化合物 PI3KC2α-IN-3PI3KC2α-IN-3

    PI3KC2α-IN-3 is a highly selective and potent PI3KC2α inhibitor with an IC50 value of 126 nM. PI3KC2α-IN-3 interacts with the ATP binding site of PI3KC2α and impairs endocytic membrane kinetics and membrane remodelling. PI3KC2α-IN-3 can be used to study thrombosis, diabetes and cancer.

    价 格：￥电议型 号：T64199产 地：中国大陆

  • T64189NNMT-IN-3；化合物 NNMT-IN-3NNMT-IN-3

    NNMT-IN-3 (compound 14) is a potent and selective inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 values of 1.1 nM and 0.4 μM in cell-free and cell-based assays, respectively. nNMT-IN-3 can be used in studies of obesity, cancer, type II diabetes and skeletal sarcopenia, among other diseases.

    价 格：￥电议型 号：T64189产 地：中国大陆

  • T64160MraY-IN-3；化合物 MraY-IN-3MraY-IN-3

    MraY-IN-3 (12a) is a potent inhibitor of the bacterial translocase MraY (IC50: 140 μM). 46 μg/ml).

    价 格：￥电议型 号：T64160产 地：中国大陆

  • T64146RORγt/DHODH-IN-3；化合物 RORγt/DHODH-IN-3RORγt/DHODH-IN-3

    RORγt/DHODH-IN-3 (compound (S)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.098 μM) and DHODH (IC50: 0.432 μM).RORγt/DHODH-IN-1 has significant in vivo anti-inflammatory effects.

    价 格：￥电议型 号：T64146产 地：中国大陆

  • T64137AChE/BuChE-IN-3；化合物 AChE/BuChE-IN-3AChE/BuChE-IN-3

    AChE/BuChE-IN-3 is a potent inhibitor of AChE (IC50: 0.65 μM) and BuChE (IC50: 5.77 μM) that crosses the blood-brain barrier and also exhibits an inhibitory effect on the aggregation of Aβ1-42. AChE/BuChE-IN-3 can be used to study Alzheimer´s disease.

    价 格：￥电议型 号：T64137产 地：中国大陆

  • T64070Pan-Trk-IN-3；化合物 Pan-Trk-IN-3Pan-Trk-IN-3

    Pan-Trk-IN-3 is a potent, broad-spectrum inhibitor of Trk and its drug-resistant mutants, acting on TrkA (IC50: 2 nM), TrkB (IC50: 3 nM), TrkC (IC50: 2 nM), TrkAG595R (IC50: 21 nM), TrkAG667C (IC50: 26 nM), TrkAG667S (IC50: 5 nM), TrkAF589L (IC50: 7 nM) and TrkCG623R (IC50: 6 nM), TrkAG667S (IC50: 5 nM), TrkAF589L (IC50: 7 nM) and TrkCG623R (IC50: 6 nM). Pan-Trk-IN-3 induces apoptosis and has significant anti-tumour effects.

    价 格：￥电议型 号：T64070产 地：中国大陆

  • T64068KIF18A-IN-3；化合物 KIF18A-IN-3KIF18A-IN-3

    KIF18A-IN-3 is a potent inhibitor of KIF18A with an IC50 value of 61 nM. KIF18A-IN-3 significantly causes mitotic arrest and increases the number of mitotic cells in tumour tissue. kIF18A-IN-3 can be used to study tumours.

    价 格：￥电议型 号：T64068产 地：中国大陆

  • T64066CSF1R-IN-3；化合物CSF1R-IN-3CSF1R-IN-3

    CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM. CSF1R-IN-3 has anti-proliferative activity against colorectal cancer cells. CSF1R-IN-3 exhibits anti-tumour effects and immune enhancing effects by inhibiting the migration of macrophages and inducing the reprogramming of M2-type macrophages to M1-type macrophages, thus exhibited activity against colorectal cancer cells.

    价 格：￥电议型 号：T64066产 地：中国大陆

  • T64061Mps1-IN-3 hydrochloride；化合物 Mps1-IN-3 hydrochlorideMps1-IN-3 hydrochloride

    Mps1-IN-3 hydrochloride is a potent and selective inhibitor of Mps1 (IC50: 50 nM). mps1-IN-3 hydrochloride exhibits inhibitory effects on the proliferation of glioblastoma cells and effectively sensitizes glioblastomas to vincristine in an in situ xenograft tumor model.

    价 格：￥电议型 号：T64061产 地：中国大陆

  • T64040Galectin-3-IN-2；化合物 Galectin-3-IN-2Galectin-3-IN-2

    Galectin-3-IN-2 is a potent inhibitor of polyvalent galactose lectin-3, with an IC50 value of 8.3 μM for Gal-3. Galectin-3 is involved in many metabolic processes associated with cancer.

    价 格：￥电议型 号：T64040产 地：中国大陆

  • T64032CYP3A4-IN-3；化合物 CYP3A4-IN-3CYP3A4-IN-3

    CYP3A4-IN-3 is a specific, highly affinity cytochrome P450 3A4 (CYP3A4) (cytochrome P450 3A4 (CYP3A4)) inhibitor (IC50: 0.075 μM). CYP3A4-IN-3 is an analogue of ritonavir with a simpler structure and twice as much inhibition as ritonavir. CYP3A4-IN-3 can be used as an antiviral agent and immunosuppressant.

    价 格：￥电议型 号：T64032产 地：中国大陆

  • T64030EGFR-IN-31；化合物 EGFR-IN-31EGFR-IN-31

    EGFR-IN-31 is a potent inhibitor of EGFR. Overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to cause uncontrollable cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-31 exhibits research potential for EGFR mutation-related diseases.

    价 格：￥电议型 号：T64030产 地：中国大陆

  • T64005PDE4B-IN-3；化合物 PDE4B-IN-3PDE4B-IN-3

    PDE4B-IN-3 is a potent inhibitor of PDE4B (IC50: 0.94 μM) and exhibits anti-inflammatory effects.

    价 格：￥电议型 号：T64005产 地：中国大陆

  • T63973hCAXII-IN-3；化合物 hCAXII-IN-3hCAXII-IN-3

    hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).

    价 格：￥电议型 号：T63973产 地：中国大陆

  • T63933CDK1-IN-3；化合物 CDK1-IN-3CDK1-IN-3

    CDK1-IN-3 (8g) is a selective CDK1 inhibitor that acts on CDK1 (IC50: 36.8 nM), CDK2 (IC50: 305.17 nM) and CDK5 (IC50: 369.37 nM). CDK1-IN-3 can affect the cell cycle and thus inhibit the growth of cancer cells and can be used in cancer research.

    价 格：￥电议型 号：T63933产 地：中国大陆

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