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T63870Multi-kinase-IN-3;化合物 Multi-kinase-IN-3Multi-kinase-IN-3
Multi-kinase-IN-3 (compound 2) is a potent inhibitor of angiokinase and inhibits VEGFR-2 (IC50: 58.3 nM) and PDGFRβ (IC50: 55 nM).
价 格:¥电议型 号:T63870产 地:中国大陆
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T63854Cathepsin C-IN-3;化合物 Cathepsin C-IN-3Cathepsin C-IN-3
Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).
价 格:¥电议型 号:T63854产 地:中国大陆
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T63850FGFR2-IN-3 hydrochloride;化合物 FGFR2-IN-3 hydrochlorideFGFR2-IN-3 hydrochloride
FGFR2-IN-3 hydrochloride is a selective, orally active FGFR2 inhibitor.
价 格:¥电议型 号:T63850产 地:中国大陆
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T63849Tubulin polymerization-IN-34;化合物 Tubulin polymerization-IN-34Tubulin polymerization-IN-34
Tubulin polymerization-IN-34 is an inhibitor of [1,2] oxazolylisoindole microtubulin polymerization and is highly selective for marginal zone lymphoma VL51 cell lines.
价 格:¥电议型 号:T63849产 地:中国大陆
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T63839IRE1α kinase-IN-3;化合物 IRE1α kinase-IN-3IRE1α kinase-IN-3
IRE1α kinase-IN-3 is a potent, ATP-competitive inhibitor of IRE1α (Ki: 480 nM).
价 格:¥电议型 号:T63839产 地:中国大陆
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T63834AAK1-IN-3 TFA;化合物 AAK1-IN-3 TFAAAK1-IN-3 TFA
AAK1-IN-3 TFA is an adaptor protein 2-associated kinase 1 (AAK1) inhibitor (IC50: 11 nM) that crosses the blood-brain barrier and is a quinoline analogue.AAK1-IN-3 has shown potential for research in neuropathic pain.
价 格:¥电议型 号:T63834产 地:中国大陆
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T63798EGFR-IN-32;化合物 EGFR-IN-32EGFR-IN-32
EGFR-IN-32 is a potent inhibitor of EGFR. EGFR-IN-32 has shown research potential for EGFR mutation-related diseases.
价 格:¥电议型 号:T63798产 地:中国大陆
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T63791HDAC-IN-36;化合物 HDAC-IN-36HDAC-IN-36
HDAC-IN-36 is an orally active HDAC (histone deacetylase) inhibitor with an IC50 value of 11.68 nM for HDAC6. HDAC-IN-36 induces apoptosis, autophagy and inhibits migration. HDAC-IN-36 exhibits antitumor and antimetastatic effects and can be used to study breast cancer. HDAC-IN-36 exhibits antitumor and antimetastatic effects and can be used to study breast cancer.
价 格:¥电议型 号:T63791产 地:中国大陆
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T63790Cbl-b-IN-3;化合物Cbl-b-IN-3Cbl-b-IN-3
Cbl-b-IN-3 is a potent proto-oncogene-B (CPL-B) inhibitor of casitas B-series lymphoma (ic50 < 1 nM). Cpl-b, a cyclic E3 ubiquitin protein ligase, is involved in the setting of T lymphocyte activation thresholds. Cpl-b negatively regulates p85 in an independent proteolytic manner, and participates in the recruitment of p85 to CD28 and T cell antigen receptor ζ through its E3 ubiquitin ligase activity. Inhibition of PI3K inhibits the enhancement of Cblb-/ -T cell activation.
价 格:¥电议型 号:T63790产 地:中国大陆
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T63753hCAIX-IN-3;化合物 hCAIX-IN-3hCAIX-IN-3
hCAII-IN-3 (compound 7e) is a selective and potent carbonic anhydrase (CA II/IX) inhibitors with their Kis values of 124.2 and 30.5 nM, respectively. hCAII-IN-1 has shown investigational potential for cancer disease.
价 格:¥电议型 号:T63753产 地:中国大陆
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T63741SGK1-IN-3;化合物 SGK1-IN-3SGK1-IN-3
SGK1-IN-3 is a potent, orally active SGK1 inhibitor. Among them, the serine/threonine kinase SGK1, an activator of the β-linked protein pathway and a powerful stimulator of cartilage degradation, has been found to be upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 shows research potential in osteoarthritis.
价 格:¥电议型 号:T63741产 地:中国大陆
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T63732EGFR-IN-3;EGFR 抑制剂 3EGFR-IN-3
EGFR-IN-3 is an EGFR inhibitor with potential antitumour activity.EGFR-IN-3 inhibits EGFRwt-TK and induces apoptosis (cell death), which can cause cells to block in the G2/M phase.
价 格:¥电议型 号:T63732产 地:中国大陆
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T63729GPX4-IN-3;化合物 GPX4-IN-3GPX4-IN-3
GPX4-IN-3 (26a) is a potent inhibitor of glutathione peroxidase 4 (GPX4), selectively inducing ferroptosis. It demonstrates a 71.7% inhibition rate of GPX4 at a concentration of 1 μM [1].
价 格:¥电议型 号:T63729产 地:中国大陆
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T63725Tubulin polymerization-IN-35;化合物 Tubulin polymerization-IN-35Tubulin polymerization-IN-35
Tubulin polymerization-IN-35 is [1,2] an inhibitor of oxazolylisoindole microtubulin polymerization that acts highly selectively on the marginal zone lymphoma VL51 cell line.
价 格:¥电议型 号:T63725产 地:中国大陆
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T63720PIM1-IN-3;化合物 PIM1-IN-3PIM1-IN-3
PIM1-IN-3 (Compound HL8) is a potent inhibitor of PIM1 that selectively inhibits the PIM-1 enzyme and effectively induces apoptosis in Colo320 cells.PIM1-IN-3 has shown research potential for cancer diseases.
价 格:¥电议型 号:T63720产 地:中国大陆
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T63694SARS-CoV-2-IN-33;化合物 SARS-CoV-2-IN-33SARS-CoV-2-IN-33
SARS-CoV-2-IN-33 is an inhibitor of COVID-19. SARS-CoV-2-IN-3 exhibits good binding affinity (-8.0 Kcal/mole) for COVID-19 major protease (Mpro) (PDB ID: 6LU7). SARS-CoV-2-IN-33 exhibits good anti-proliferative effects on cancer cells. SSARS-CoV-2-IN-33 can be used to study cancer and COVID-19.
价 格:¥电议型 号:T63694产 地:中国大陆
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T63679SARS-CoV-2 3CLpro-IN-3;化合物 SARS-CoV-2 3CLpro-IN-3SARS-CoV-2 3CLpro-IN-3
SARS-CoV-2 3CLpro-IN-3 is a SARS CoV-2 3CLpro inhibitor that exhibits antiviral, antibacterial, and antifungal effects.
价 格:¥电议型 号:T63679产 地:中国大陆
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T63625USP1-IN-3;化合物 USP1-IN-3USP1-IN-3
USP1-IN-3 is a selective inhibitor of USPI that inhibits USPI-UAFI (IC50<30 nM). USP1-IN-3 can be used to study cancer.
价 格:¥电议型 号:T63625产 地:中国大陆
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T63620LRRK2-IN-3;化合物 LRRK2-IN-3LRRK2-IN-3
LRRK2-IN-3 is a potent, selective, orally active LRRK2 inhibitor that crosses the blood-brain barrier with an IC50 value of 0.6 nM in hPBMCs. LRRK2-IN-3 can be used to study Parkinson´s disease.
价 格:¥电议型 号:T63620产 地:中国大陆
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T63611Tubulin polymerization-IN-32;化合物 Tubulin polymerization-IN-32Tubulin polymerization-IN-32
Tubulin polymerization-IN-32 is a tubulin polymerization inhibitor that inhibits the proliferation of cancer cells and can be used to study cancers such as lymphoma.
价 格:¥电议型 号:T63611产 地:中国大陆