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T73400LPG-11047 2HCl；PG-11047二盐酸盐PG-11047 2HCl(949933-50-0 Free base)|||CGC-11047 2HCl；PG-11047 2HCl(949933
PG-11047 2HCl is an apoptosis-stimulating agent used in the treatment of genitourinary disorders, immune system disorders, genetic disorders and malformations, ocular disorders, and disorders of the blood and lymphatic systems, and in the study of lymphomas and prostate cancer.
价 格：￥电议型 号：T73400L产 地：中国大陆
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T73337Articaine；化合物 ArticaineHoe-045 free base；Hoe-045 free base
Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-gated sodium channels located in the nerve´s inner cavity. Furthermore, Articaine mitigates LPS-induced acute kidney injury through the suppression of NF-κB activation and inhibition of the NLRP3 inflammasome pathway.
价 格：￥电议型 号：T73337产 地：中国大陆
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T73214RX 801077；化合物 RX 8010772 BFI free base；2 BFI free base
RX 801077 (2 BFI free base), a selective imidazoline I2 receptor (I2R) agonist, exhibits a K i value of 70.1 nM, demonstrating anti-inflammatory and neuroprotective properties. This compound holds research potential for traumatic brain injury (TBI).
价 格：￥电议型 号：T73214产 地：中国大陆
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T72947JBSNF-000028；化合物JBSNF-000028JBSNF-000028 free base；JBSNF-000028 free base
JBSNF-000028 is an orally active and potent nicotinamide N-methyltransferase (NNMT) inhibitor with inhibitory effects on human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT) with IC50s of 0.033 μM, 0.19 μM, and 0.21 μM, respectively.JBSNF-000028 can drive insulin sensitization and weight loss. 000028 drives insulin sensitization, glucose regulation and weight loss and can be used to study metabolic disorders.
价 格：￥电议型 号：T72947产 地：中国大陆
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T7284Argipressin acetate (113-79-1(free base))；醋酸精氨加压素Argipressin acetate (113-79-1(free base))
Vasopressin acetate is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively
价 格：￥电议型 号：T7284产 地：中国大陆
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T72784LOTUB1/USP8-IN-1 HCl；OTUB1/USP8抑制剂1盐酸盐OTUB1/USP8-IN-1 HCl（2858800-98-1 Free base）；OTUB1/USP8-IN-1 HCl
OTUB1/USP8-IN-1 HCL is a potent dual inhibitor of OTUB1 and USP8 with potential antitumour activity, inhibiting both OTUB1 and USP8. OTUB1/USP8-IN-1 may be used in the study of leukaemia.
价 格：￥电议型 号：T72784L产 地：中国大陆
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T72548IGUANA-1 free base；化合物 IGUANA-1 free baseSTL5-T-0057；STL5-T-0057
IGUANA-1 free base (STL5-T-0057) acts as a selective ALDH1 B1 inhibitor, demonstrating an IC50 value of 30 nM. It efficaciously inhibits the growth of SW480 cells under both adherent and spheroid conditions, yielding IC50 values of 2.46 μM and 0.39 μM, respectively. This compound is utilized in cancer research.
价 格：￥电议型 号：T72548产 地：中国大陆
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T72543BOLD-100 free base；化合物 BOLD-100 free baseNKP-1339 free base ; IT-139 free base ; KP-1339 free base
BOLD-100 free base (NKP-1339; IT-139), a ruthenium-based anticancer agent, inhibits stress-induced GRP78 upregulation, thus disrupting endoplasmic reticulum (ER) homeostasis. This action induces ER stress and unfolded protein response (UPR), interfering with the intricate relationship between ER-stress response, lysosome dynamics, and autophagy execution.
价 格：￥电议型 号：T72543产 地：中国大陆
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T72520GR 89696 free base；化合物 GR 89696 free baseGR 89696 free base
GR 89696 free base is a potent κ2 opioid receptor agonist with a high selectivity, offering potential benefits in pruritus prevention.
价 格：￥电议型 号：T72520产 地：中国大陆
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T72517ERK-IN-2 free base；化合物 ERK-IN-2 free baseERK-IN-2 free base
ERK-IN-2 free base, an inhibitor of ERK2, demonstrates potent efficacy with an IC50 value of 1.8 nM. However, doses exceeding 10 μM may result in off-target toxicity and/or activity.
价 格：￥电议型 号：T72517产 地：中国大陆
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T72513SC 51089 free base；化合物 SC 51089 free baseSC 51089 free base
SC 51089 free base is a selective antagonist of the prostaglandin E2 EP1 receptor, demonstrating neuroprotective activity. It exhibits binding affinities (Kis) of 1.3 μM for EP1, 11.2 μM for TP, 17.5 μM for EP3, and 61.1 μM for FP receptors, respectively.
价 格：￥电议型 号：T72513产 地：中国大陆
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T72091ADRA1D receptor antagonist 1 free base；化合物 ADRA1D receptor antagonist 1 free baseADRA1D receptor ant
ADRA1D receptor antagonist 1 (free base) antagonist ( K i =1.6 nM). ADRA1D receptor antagonist 1 (free base) dose-dependently inhibits bladder contraction with an IC 30 value of 15 nM. ADRA1D receptor antagonist 1 (free base) can be used in studies of overactive bladder disorders such as urinary urgency, frequency and incontinence.
价 格：￥电议型 号：T72091产 地：中国大陆
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T72058LCDD-1102 HCl；CDD-1102盐酸盐CDD-1102 HCl(2757619-84-2 Free base)；CDD-1102 HCl(2757619-84-2 Free base)
CDD-1102 HCl is a novel BRDT-BD4 / BRD2-BD1302 selective inhibitor that shows non-hormonal contraceptive potential in ex vivo experiments.
价 格：￥电议型 号：T72058L产 地：中国大陆
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T72038YM-58790；化合物YM-58790YM-58790 free base；YM-58790 free base
YM-58790 free base is a potent mAChR antagonist.YM-58790 free base inhibited M1 mAChR, M2 mAChR, and M3 mAChR with Ki values of 28 nM, 260 nM, and 15 nM, respectively.YM-58790 free base inhibits reflex rhythmic bladder contraction in rats by inhibiting bladder pressurization. YM-58790 free base inhibits reflex rhythmic bladder contractions in rats by inhibiting bladder pressurization.
价 格：￥电议型 号：T72038产 地：中国大陆
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T71945Eleclazine free base；化合物 Eleclazine free baseEleclazine free base
Eleclazine, also known as GS-6615, is a selective late sodium current inhibitor. Eleclazine is potentially useful for treatment of coronary vasodilators, antiarrhythmics and vasodilators. Eleclazin showed a shortening of the QTc interval (the time interval between the start of the Q-wave and end of the T-wave in the heart’s electrical cycle) in patients with long QT-3 (LQT3) syndrome. LQT3 is a genetic disorder that prolongs the heart’s QTc interval and can cause life-threatening cardiac arrhyth
价 格：￥电议型 号：T71945产 地：中国大陆
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T71904Chlormadinone (free base)；化合物 Chlormadinone (free base)Chlormadinone (free base)
Chlormadinone (free base) is a synthetic steroid hormone and antagonist at androgen and estrogen receptors used to treat BPH and polycystic ovary syndrome. It also promotes osteoblast differentiation and Ca deposition in bone marrow stem cells.
价 格：￥电议型 号：T71904产 地：中国大陆
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T71772Bicifadine free base；化合物 Bicifadine free baseCL-220075|||Bicifadine free base|||CL220075|||Bicifadin
Bicifadine, also known as DOV-220075, CL 220,075, is a SNDR inhibitor potentially for the treatment of lower back pain. Bicifadine has a non-opioid, non-NSAID mechanism for the treatment of pain, which should have less abuse potential than opioid drugs and less propensity to cause gastric ulcers than NSAID drugs. While the drug is purported to be a serotonin (SERT) and noradrenaline transporter (NET) inhibitor, it also has effects at the dopamine transporter (DAT), effectively making it a broad
价 格：￥电议型 号：T71772产 地：中国大陆
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T7173L[Leu5]-Enkephalin acetate(58822-25-6 free base)；亮氨酸脑啡肽Leucine enkephalin|||Leu-enkephalin|||Leucyl-e
[Leu5]-Enkephalin acetate(58822-25-6 free base) is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)
价 格：￥电议型 号：T7173L产 地：中国大陆
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T71728NW-1772 free base；化合物 NW-1772 free baseNW-1772 free base
NW-1772 free base is a monoamine oxidase B inhibitor.
价 格：￥电议型 号：T71728产 地：中国大陆
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T71709MDL-72527 free base；化合物 MDL-72527 free baseMDL-72527 free base
MDL-72527 free base is a polyamine oxidase inactivator.
价 格：￥电议型 号：T71709产 地：中国大陆
