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T79565Sirt1/2-IN-4；化合物 Sirt1/2-IN-4Sirt1/2-IN-4
Sirt1/2-IN-4 (compound PS3) is a potent triple inhibitor of SIRT1, SIRT2, and SIRT3, exhibiting IC50 values of 1.2 μM (SIRT1), 1.9 μM (SIRT2), and 18.6 μM (SIRT3), respectively. It effectively inhibits p53 deacetylation, indicating potential anticancer properties [1].
价 格：￥电议型 号：T79565产 地：中国大陆
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T79564Sirt1/2-IN-3；化合物 Sirt1/2-IN-3Sirt1/2-IN-3
Sirt1/2-IN-3 (compound PS9) serves as a dual inhibitor of SIRT1/2, exhibiting IC50 values of 1.4 μM (SIRT1) and 2.0 μM (SIRT2), respectively. This compound effectively inhibits p53 deacetylation while simultaneously elevating p53 and α-tubulin acetylation levels. Additionally, Sirt1/2-IN-3 promotes apoptosis and exhibits antiproliferative effects on human leukemia cell lines [1].
价 格：￥电议型 号：T79564产 地：中国大陆
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T79563Sirt1/2-IN-2；化合物 Sirt1/2-IN-2Sirt1/2-IN-2
Sirt1/2-IN-2 (compound hsa55) serves as a dual inhibitor for SIRT1 with an IC50 of 1.8 μM and SIRT2 with an IC50 of 2.4 μM, respectively. It effectively inhibits p53 deacetylation while enhancing the acetylation of p53 and α-tubulin. The compound also promotes apoptosis and exhibits anti-proliferative effects on human leukemia cell lines [1].
价 格：￥电议型 号：T79563产 地：中国大陆
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T78787PARP-1/2-IN-2；化合物 PARP-1/2-IN-2PARP-1/2-IN-2
PARP-1/2-IN-2-IN-1 (Compound 12e) effectively inhibits PARP1/2 and CDK12 with IC 50 values of 34 nM, 30 nM, and 285 nM respectively, impairing DNA damage repair and inducing cell cycle arrest and apoptosis. This compound also hampers the proliferation of TNBC cells and the growth of TNBC xenograft tumors [1].
价 格：￥电议型 号：T78787产 地：中国大陆
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T78190ERK1/2 inhibitor 9；化合物 ERK1/2 inhibitor 9ERK1/2 inhibitor 9
ERK1/2 Inhibitor 9 (Probe 1), a covalent antagonist of ERK1/2, exhibits sub-micromolar efficacy in cellular assays (A375 GI50=0.47 μM) and facilitates the reduction of phospho-ERK1/2 levels. When conjugated with trans-cyclo-octene (TCO) and Tz-Thalidomide (tetrazine-tagged Thalidomide), it forms the corresponding ERK-CLIPTAC, promoting targeted ERK1/2 degradation [1].
价 格：￥电议型 号：T78190产 地：中国大陆
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T77504JAK1/2/3 Inhibitor 1；化合物 JAK1/2/3 Inhibitor 1JAK1/2/3 Inhibitor 1
JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell lines. It inhibits the growth of cancer cells by binding to the cancer cell backbone and inhibiting the production of new proteins.
价 格：￥电议型 号：T77504产 地：中国大陆
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T7663LAngiotensin 1/2 (1-9) TFA；Angiotensin 1/2 (1-9) TFA 三氟乙酸盐Angiotensin 1/2 (1-9) TFA (34273-12-6 free
Angiotensin 1/2 (1-9)TFA is containing the amino acids 1-9 that are converted from Angiotensin I/II peptide.
价 格：￥电议型 号：T7663L产 地：中国大陆
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T7663Angiotensin 1/2 (1-9)；血管紧张素IAngiotensin 1/2 (1-9)
Angiotensin 1/2 (1-9) is containing the amino acids 1-9 that are converted from Angiotensin I/II peptide.
价 格：￥电议型 号：T7663产 地：中国大陆
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T74894SIRT1/2/3-IN-1；化合物 SIRT1/2/3-IN-1SIRT1/2/3-IN-1
SIRT1/2/3-IN-1 (compound 10) is a potent, selective, and cell-permeable inhibitor targeting SIRT1, SIRT2, and SIRT3, demonstrating inhibitory concentrations (IC50s) of 0.54 μM, 0.253 μM, and 0.72 μM, respectively. It is utilized in cancer research [1].
价 格：￥电议型 号：T74894产 地：中国大陆
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T74374ERK1/2 inhibitor 4；化合物 ERK1/2 inhibitor 4ERK1/2 inhibitor 4
ERK1/2 Inhibitor 5, a potent suppressant of the ERK1/2 pathway, is instrumental in the mitogen-activated protein kinase (MAPK) signal transduction pathway, where extracellular signal-regulated kinase (ERK) serves as a critical component of the MAPK family. This compound holds promise for the investigation or mitigation of cancer, inflammation, or various proliferative diseases[1].
价 格：￥电议型 号：T74374产 地：中国大陆
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T74373ERK1/2 inhibitor 3；化合物 ERK1/2 inhibitor 3ERK1/2 inhibitor 3
ERK1/2 Inhibitor 3, a potent inhibitor of ERK1/2, plays a crucial role in the signal transduction pathway by targeting the Mitogen-activated protein kinase (MAPK) family, specifically the extracellular signal-regulated kinase (ERK). Given its significant impact, this compound holds promise for research or prevention efforts related to cancer, inflammation, or other proliferative diseases[1].
价 格：￥电议型 号：T74373产 地：中国大陆
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T72957DRAK1/2-IN-1；化合物 DRAK1/2-IN-1DRAK1/2-IN-1
DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 ?M and 6 ?M, respectively.
价 格：￥电议型 号：T72957产 地：中国大陆
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T72922TNKS1/2-IN-1；化合物 TNKS1/2-IN-1TNKS1/2-IN-1
TNKS1/2-IN-1 is a potent inhibitor of tankyrase (TNKS1/2), exhibiting pIC50 values between 7.1-8.2. It is utilized in research targeting cancer, fibrosis, and other hyperproliferative diseases.
价 格：￥电议型 号：T72922产 地：中国大陆
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T72473NOD1/2 antagonist-1；化合物 NOD1/2 antagonist-1NOD1/2 antagonist-1
NOD1/2 Antagonist-1 is a potent dual inhibitor of nucleotide-binding oligomerization domain-like receptors 1 and 2 (NOD1/2), displaying inhibitory concentrations (IC50) of 1.13 μM for NOD1 and 0.77 μM for NOD2. It exhibits an acceptable half-life (T1/2) of 67.6 minutes. Additionally, NOD1/2 Antagonist-1 enhances the antitumor efficiency of Paclitaxel (PTX).
价 格：￥电议型 号：T72473产 地：中国大陆
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T72437PARP1/2/TNKS1/2-IN-1；PARP1/2/TNKS1/2抑制剂1PARP1/2/TNKS1/2-IN-1
PARP1/2/TNKS1/2-IN-1 is a multi-target inhibitor of PARP-1, PARP-2, TNKS1 and TNKS2.PARP1/2/TNKS1/2-IN-1 has potential anti-tumor activity and induces apoptosis.
价 格：￥电议型 号：T72437产 地：中国大陆
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T64662MDH1/2 inhibitor compound 16c；化合物 MDH1/2 inhibitor compound 16cMDH1/2 inhibitor compound 16c
MDH1/2 inhibitor compound 16c is a useful organic compound for research related to life sciences and the catalog number is T64662.
价 格：￥电议型 号：T64662产 地：中国大陆
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T64608Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb #4376R；化合物 Phospho-p44/42 MAPK (Erk1
Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb #4376R is a useful organic compound for research related to life sciences and the catalog number is T64608.
价 格：￥电议型 号：T64608产 地：中国大陆
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T64587p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R；化合物 p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695Rp44
p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R is a useful organic compound for research related to life sciences and the catalog number is T64587.
价 格：￥电议型 号：T64587产 地：中国大陆
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T64155ERK1/2 inhibitor 5；化合物 ERK1/2 inhibitor 5ERK1/2 inhibitor 5
ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. ERK1/2 inhibitor 5 has the potential to investigate or prevent cancer, inflammation or other proliferative diseases.
价 格：￥电议型 号：T64155产 地：中国大陆
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T64147ERK1/2 inhibitor 6；化合物 ERK1/2 inhibitor 6ERK1/2 inhibitor 6
ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2. ERK1/2 inhibitor 6 has shown potential for the study or prevention of cancer, inflammation or other proliferative diseases.
价 格：￥电议型 号：T64147产 地：中国大陆
