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T63961ACC1/2-IN-1；化合物 ACC1/2-IN-1ACC1/2-IN-1
ACC1/2-IN-1 is a potent inhibitor of ACC1/2 and acts on ACC1 (IC50: 98.06 nM) and ACC2 (IC50: 29.43 nM). ACC1/2-IN-1 can be used in cancer research.
价 格：￥电议型 号：T63961产 地：中国大陆
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T63707BRD4-BD1/2-IN-2；化合物 BRD4-BD1/2-IN-2BRD4-BD1/2-IN-2
BRD4-BD1/2-IN-2 is a potent inhibitor of BRD4-BD2, capable of acting on both BRD4 BD2 (IC50<0.5 nM) and BRD4 BD1 (IC50<300 nM).
价 格：￥电议型 号：T63707产 地：中国大陆
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T63651IDO1/2-IN-1 hydrochloride；化合物 IDO1/2-IN-1 hydrochlorideIDO1/2-IN-1 hydrochloride
IDO1/2-IN-1 hydrochloride is the first potent dual inhibitor of IDO1 (IC50: 28 nM) and IDO2 (IC50: 144 nM) that is orally active.IDO1/2-IN-1 hydrochloride exhibits antitumor effects.
价 格：￥电议型 号：T63651产 地：中国大陆
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T63547MEK1/2-IN-2；化合物 MEK1/2-IN-2MEK1/2-IN-2
MEK1/2-IN-2 is a potent, ATP-competitive MEK1/2 inhibitor that exhibits equal inhibitory effects on wild-type MEK1/2 and a group of MEK1/2 mutant cells.
价 格：￥电议型 号：T63547产 地：中国大陆
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T63331ERK1/2 inhibitor 8；化合物 ERK1/2 inhibitor 8ERK1/2 inhibitor 8
ERK1/2 inhibitor 8 is a potent inhibitor of ERK that acts on ERK2 (IC50: 0.48 nM).
价 格：￥电议型 号：T63331产 地：中国大陆
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T63222IDO1/2-IN-1；化合物 IDO1/2-IN-1IDO1/2-IN-1
IDO1/2-IN-1 is the first potent, orally active dual IDO1/IDO2 inhibitor, exhibiting antitumor effects with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively.
价 格：￥电议型 号：T63222产 地：中国大陆
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T63209HDAC1/2 and CDK2-IN-1；化合物 HDAC1/2 and CDK2-IN-1HDAC1/2 and CDK2-IN-1
HDAC1/2 and CDK2-IN-1 (compound 14d) are potent inhibitors of HDAC1, HDAC2 and CDK2 with IC50 values of 70.7, 23.1 and 0.80 μM, respectively. HDAC1/2 and CDK2-IN-1 are able to block the cell cycle and induce apoptosis. They showed good anti-tumor effects in vivo.
价 格：￥电议型 号：T63209产 地：中国大陆
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T62933ERK1/2 inhibitor 7；化合物 ERK1/2 inhibitor 7ERK1/2 inhibitor 7
ERK1/2 inhibitor 7 is a potent inhibitor of ERK, acting on ERK2 (IC50: 0.94 nM).
价 格：￥电议型 号：T62933产 地：中国大陆
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T62830SGLT1/2-IN-1；化合物 SGLT1/2-IN-1SGLT1/2-IN-1
SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor.
价 格：￥电议型 号：T62830产 地：中国大陆
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T62686MNK1/2-IN-6；化合物 MNK1/2-IN-6MNK1/2-IN-6
MNK1/2-IN-6 is a potent and selective inhibitor of MNK1 (IC50: 2.3 nM), MNK2 (IC50: 3.4 nM), and MNK1/2-IN-6 induces apoptosis in a concentration-dependent manner.
价 格：￥电议型 号：T62686产 地：中国大陆
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T62508PARP-1/2-IN-1；化合物 PARP-1/2-IN-1PARP-1/2-IN-1
PARP-1-/2-IN-1 is a potent inhibitor of PARP-1 (IC50: 0.51 nM) and PARP-2 (IC50: 23.11 nM).
价 格：￥电议型 号：T62508产 地：中国大陆
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T62468CB1/2 agonist 1；化合物 CB1/2 agonist 1CB1/2 agonist 1
CB1/2 agonist 1 is a potent CB1/2 agonist that crosses the blood-brain barrier, acting on CB1R (EC50: 56.15 nM) and CB2R (EC50: 11.63 nM). CB1/2 agonist 1 reduces glutamate release and LPS-induced microglia activation, and has anti-inflammatory and analgesic activities. CB1/2 agonist 1 has potential for multiple sclerosis studies.
价 格：￥电议型 号：T62468产 地：中国大陆
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T62456ALR1/2-IN-1；化合物 ALR1/2-IN-1ALR1/2-IN-1
ALR1/2-IN-1 (Compound 6e) is an aldehyde reductase (ALR1) (IC50: 3.26 μM) and aldose reductase (ALR2) (IC50: 3.06 μM) inhibitor with anticancer effects.
价 格：￥电议型 号：T62456产 地：中国大陆
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T62411CB1/2 agonist 4；化合物 CB1/2 agonist 4CB1/2 agonist 4
CB1/2 agonist 4 (compound 24) is a CB1 full agonist (EC50: 15.09 nM) and a CB2 partial agonist (EC50: 1.16 nM). CB1/2 agonist 4 has significant anti-harm-sensing activity and also activates cannabinoid and TRPV1 receptors (IC50: 0.8 μM, EC50: 0.12 μM). , EC50: 0.12 μM).
价 格：￥电议型 号：T62411产 地：中国大陆
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T62240Sirt1/2-IN-1；化合物 Sirt1/2-IN-1Sirt1/2-IN-1
Sirt1/2-IN-1 (Compound 7) is an inhibitor of SIRT1 and SIRT2 and is capable of acting on SIRT1 (IC50: 1.81 μg/mL), SIRT2 (IC50: 2.10 μg/mL) and SIRT3 (IC50: 20.5 μg/mL) and has α-microtubulin hyperacetylation activity ( Sirt1/2-IN-1 exhibited significant anticancer effects.
价 格：￥电议型 号：T62240产 地：中国大陆
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T62180CB1/2 agonist 2；化合物 CB1/2 agonist 2CB1/2 agonist 2
CB1/2 agonist 2 (compound 23) is a potent non-selective cannabinoid ligand with Ki of 3.5 nM and 1.2 nM, respectively. CB1/2 agonist 2 is a full agonist of CB1 and a competitive inverse agonist of CB2. BACE-IN-1 is a complete agonist of CB1 and a competitive inverse agonist of CB2.
价 格：￥电议型 号：T62180产 地：中国大陆
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T61978ACC1/2-IN-2；化合物 ACC1/2-IN-2ACC1/2-IN-2
ACC1/2-IN-2 (compound PF-3) is a potent inhibitor of ACC1/2 with IC50s of 22 and 48 nM for ACC1 and ACC2, respectively. ACC1/2-IN-2 shows antiproliferation activity and has research value in cancer research.
价 格：￥电议型 号：T61978产 地：中国大陆
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T61956BACE1/2-IN-1；化合物 BACE1/2-IN-1BACE1/2-IN-1
BACE1/2-IN-1 (compound 34) is an effective BACE1 and BACE2 inhibitor with IC50 of 0.01 and 0.0053 μM, respectively. BACE1/2-IN-1 has lower Pgp efflux ratio and improved passive permeability. The metabolic stability of BACE1/2-IN-1 in liver microsomes is decreased.
价 格：￥电议型 号：T61956产 地：中国大陆
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T61865COX-1/2-IN-2；化合物 COX-1/2-IN-2COX-1/2-IN-2
COX-1/2-IN-2 is a potent inhibitor of both COX-1 and COX-2, displaying significant inhibitory effects with IC50 values of 9.7 ± 0.09 μM for COX-1 and 4.6 ± 1.45 μM for COX-2, respectively [1].
价 格：￥电议型 号：T61865产 地：中国大陆
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T61791BRD4-BD1/2-IN-1；化合物 BRD4-BD1/2-IN-1BRD4-BD1/2-IN-1
BRD4-BD1/2-IN-1 is a highly effective inhibitor of BRD4, specifically targeting the BRD4 BD-1 and BRD4 BD-2 domains with IC 50 values of <100 nM each (US20150148375A1, compound 5) [1].
价 格：￥电议型 号：T61791产 地：中国大陆
