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T6076EPZ015666EPZ015666,GSK3235025,
EPZ015666 is an orally available inhibitor of PRMT5 enzymatic activity.
价 格:¥电议型 号:T6076产 地:美洲
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T8499eCF506;化合物eCF506eCF506
eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)
价 格:¥电议型 号:T8499产 地:中国大陆
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T82489eIF4E-IN-6;化合物 eIF4E-IN-6eIF4E-IN-6
eIF4E-IN-6 (Compound 4b), a GMP analog, is designed to inhibit the eIF4E protein´s ability to bind to cap mRNA. It demonstrates cytotoxic effects on Caco-2, HepG-2, and MCF-7 cell lines with IC50 values of 31, 27, and 21 μM, respectively [1].
价 格:¥电议型 号:T82489产 地:中国大陆
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T79382ER degrader 6;化合物 ER degrader 6ER degrader 6
ER degrader 6 (compound 35s) is a potent selective estrogen receptor modulator (SERM) with the capacity to degrade Estrogen Receptor (ER)α. It disrupts the microtubule network, inhibiting tubulin polymerization, and effectively suppresses tumor growth with minimal toxicity [1].
价 格:¥电议型 号:T79382产 地:中国大陆
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T78862EGFR-IN-86;化合物 EGFR-IN-86EGFR-IN-86
EGFR-IN-86 (compound 4i), an EGFR inhibitor (IC50: 1.5 nM), demonstrates potent activity against glioblastoma by inducing apoptosis and causing G2/M phase cell cycle arrest in U87 cells [1].
价 格:¥电议型 号:T78862产 地:中国大陆
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T78676ERα degrader 6;化合物 ERα degrader 6ERα degrader 6
ERα degrader 6 (Compound 31q) is an ERα degrader with a K I of 75 nM and also inhibits ARO with an IC50 value of 37.7 nM. It effectively inhibits tumor growth in the MCF-7 tumor xenograft model and has applications in breast cancer research [1].
价 格:¥电议型 号:T78676产 地:中国大陆
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T78169Enpp-1-IN-16;Enpp-1抑制剂16Enpp-1-IN-16
Enpp-1-IN-16 is an inhibitor targeting ENPP1 with potential anti-cancer activity.Enpp-1-IN-16 can be used to study insulin resistance in relation to type II diabetes mellitus and various ENPP1-mediated diseases in the chondrocalcinosis and osteoarthritis classes.
价 格:¥电议型 号:T78169产 地:中国大陆
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T77731ERK5-IN-6;ERK5抑制剂6ERK5-IN-6
ERK5-IN-6 is a potent inhibitor of ERK5 kinase.ERK5-IN-6 exhibits antiproliferative activity, anticonvulsant activity, and antitumor activity, and can be used in the study of central nervous system-related disorders.
价 格:¥电议型 号:T77731产 地:中国大陆
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T75555(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol;化合物 (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol(6E,12E)-
(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol is an antibacterial compound. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol can be isolated from the roots of Atractylodes japonica. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol has anti-methicillin-resistant Staphylococcus aureus (MRSA) activity with MIC values of 4-32 μg/mL. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol can be used for the research of bacterial infection [1] .
价 格:¥电议型 号:T75555产 地:中国大陆
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T75120EGFR-IN-76;化合物EGFR-IN-76EGFR-IN-76
EGFR-IN-76 is a potent EGFR inhibitor.
价 格:¥电议型 号:T75120产 地:中国大陆
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T74997ERK-IN-6;化合物 ERK-IN-6ERK-IN-6
ERK-IN-6 (compound 6g) serves as a potent anti-proliferative agent against esophageal squamous cell carcinoma (ESCC), inducing apoptosis through the ERK pathway. This compound has potential applications in ESCC research [1].
价 格:¥电议型 号:T74997产 地:中国大陆
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T72236erythro-Austrobailignan-6;化合物 erythro-Austrobailignan-6erythro-Austrobailignan-6
Erythro-Austrobailignan-6, an orally active anti-cancer agent, inhibits DNA topoisomerase I and II activity, induces cell apoptosis, and enhances the phosphorylation of p38 and JNK.
价 格:¥电议型 号:T72236产 地:中国大陆
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T70951ELND006;化合物 ELND006ELND006
ELND006 is a novel gamma secretase inhibitor previously under investigation for the oral treatment of Alzheimer´s disease. ELND006 shows poor solubility and has moderate to high permeability. The in vivo performance of the ELND006 nanosuspension was tested in fed and fasted beagle dogs and compared with a gelatin capsule containing reference API. The results show that nanosizing ELND006 profoundly improved the oral bioavailability and virtually eliminated variation resulting from food inta
价 格:¥电议型 号:T70951产 地:中国大陆
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T70906EHT-6706;化合物 EHT-6706EHT-6706
EHT-6706 is a novel microtubule-disrupting agent that targets the colchicine-binding site to inhibit tubulin polymerization. At low nM concentrations, EHT 6706 exhibits highly potent antiproliferative activity on more than 60 human tumor cell lines, even those described as being drug resistant. EHT 6706 also shows strong efficacy as a vascular-disrupting agent, since it prevents endothelial cell tube formation and disrupts pre-established vessels, changes the permeability of endothelial cell mon
价 格:¥电议型 号:T70906产 地:中国大陆
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T70412PNU-145156E free base;化合物 PNU-145156E free basePNU-145156E free base
PNU-145156E free base is an angiogenesis inhibitor.
价 格:¥电议型 号:T70412产 地:中国大陆
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T6S1688(1E,6E)-Bis(demethoxy)curcumin;双去甲氧基姜黄素Curcumin III|||Didemethoxycurcumin|||BDMC;(1E,6E)-1,7-双(4-羟基苯
(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.
价 格:¥电议型 号:T6S1688产 地:中国大陆
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T65944(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]pyrimidin-5-yl]-3,5-di
(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester is a useful organic compound for research related to life sciences. The catalog number is T65944 and the CAS number is 355806-00-7.
价 格:¥电议型 号:T65944产 地:中国大陆
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T6541Ibutilide Fumarate;富马酸伊布利特Corvert Fumarate|||U70226E;Corvert Fumarate|||U70226E|||富马酸伊布利特
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action potential duration and refractory periods. Ibutilide slightly decreases the sinus rate and atrioventricular (AV) conduction and produces a dose-related prolongation of the QT interval.
价 格:¥电议型 号:T6541产 地:中国大陆
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T64147ERK1/2 inhibitor 6;化合物 ERK1/2 inhibitor 6ERK1/2 inhibitor 6
ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2. ERK1/2 inhibitor 6 has shown potential for the study or prevention of cancer, inflammation or other proliferative diseases.
价 格:¥电议型 号:T64147产 地:中国大陆
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T63571EGFR-IN-26;化合物 EGFR-IN-26EGFR-IN-26
EGFR-IN-26 is an EGFR inhibitor that can be used in cancer research.
价 格:¥电议型 号:T63571产 地:中国大陆