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  • T63431EGFR-IN-46;化合物 EGFR-IN-46EGFR-IN-46

    EGFR-IN-46 is a potent dual inhibitor of EGFR (IC50: 20.17 nM) and FAK (IC50: 14.25 nM) that significantly inhibits the growth of cancer cells and induces apoptosis.

    价 格:¥电议型 号:T63431产 地:中国大陆

  • T63303EB-0176;化合物 EB-0176EB-0176

    EB-0176 is an N-substituted valerian derivative that exhibits broad-spectrum antiviral activity and is a potent ER α-glucosidase (α-Glu) I and II inhibitor with IC50s of 0.6439 and 0.0011 μM, respectively.EB-0176 exhibits investigational potential as a broad-spectrum drug against existing and emerging viruses.

    价 格:¥电议型 号:T63303产 地:中国大陆

  • T63265EGFR-IN-36;化合物 EGFR-IN-36EGFR-IN-36

    EGFR-IN-36 is a potent inhibitor of EGFR, capable of acting on EGFR (WT) (IC50: 19.09 nM), HER2 (WT) (IC50: 120.01 nM), HER2 (A775_G776insYVMA) (IC50: 2.35 nM). EGFR-IN-36 exhibits the potential to study wild and/or mutant EGFR and/or HER2 kinase-mediated tumors.

    价 格:¥电议型 号:T63265产 地:中国大陆

  • T63170EB-0156;化合物 EB-0156EB-0156

    EB-0156 is a potent inhibitor of ER α-glucosidase (α-Glu) I and II with IC50 values of 0.0479 and <0.001 μM, respectively. EB-0156 is an N-substituted valerian derivative with broad-spectrum antiviral activity. EB-0156 has potential for broad-spectrum drug discovery against existing and emerging viruses.

    价 格:¥电议型 号:T63170产 地:中国大陆

  • T62953Estrogen receptor antagonist 6;化合物 Estrogen receptor antagonist 6Estrogen receptor antagonist 6

    Estrogen receptor antagonist 6 is a potent antagonist of the Estrogen receptor. Estrogen receptor is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and mediates the induction of a variety of biological effects. Compound 166).

    价 格:¥电议型 号:T62953产 地:中国大陆

  • T62903Enpp-1-IN-6;化合物 Enpp-1-IN-6Enpp-1-IN-6

    Enpp-1-IN-6 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). Enpp-1-IN-6 has the potential to be used in cancer and infectious disease research.

    价 格:¥电议型 号:T62903产 地:中国大陆

  • T62884eIF4A3-IN-6;化合物 eIF4A3-IN-6eIF4A3-IN-6

    eIF4A3-IN-6 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A) (e.g. eIF4AI and eIF4AII). eIF4A3-IN-6 has the potential to be investigated in eIF4A-dependent diseases, including cancer.

    价 格:¥电议型 号:T62884产 地:中国大陆

  • T62458EGFR-IN-56;化合物 EGFR-IN-56EGFR-IN-56

    EGFR-IN-56 (Compound 13a) is a potent inhibitor of EGFR, acting on EGFRT790M (IC50: 541.7 nM) and EGFRT790M/L858R (IC50: 132.1 nM). EGFR-IN-56 blocks the cell cycle of cancer cells in the G2/M phase and induces EGFR-IN-56 blocks the G2/M phase of the cancer cell cycle and induces apoptosis.

    价 格:¥电议型 号:T62458产 地:中国大陆

  • T61732EGFR/HER2-IN-6;化合物 EGFR/HER2-IN-6EGFR/HER2-IN-6

    EGFR/HER2-IN-6 (compound 43) is a dual EGFR/HER2 and DHFR inhibitor with potent activity against EGFR kinase, HER2 kinase, and DHFR, characterized by IC50 values of 0.122 μM, 0.078 μM, and 0.585 μM, respectively. This compound displays notable anticancer properties in various cancer cell lines, while demonstrating a favorable safety profile and selectivity indices. Consequently, EGFR/HER2-IN-6 holds promise as a valuable tool in cancer research [1].

    价 格:¥电议型 号:T61732产 地:中国大陆

  • T4S0176Alnustone;桤木酮(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one;(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one|||桤木酮

    Alnustone ((4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one) exerts significant anti-inflammatory activity in the assay of carrageenin-induced hind paw edema in rats.

    价 格:¥电议型 号:T4S0176产 地:中国大陆

  • T4206E6446;化合物E6446E6446

    E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to challenge doses of cytidine-phosphate-guanidine (CpG)-containing DNA, which stimulates TLR9.

    价 格:¥电议型 号:T4206产 地:中国大陆

  • T40893Estrogen receptor modulator 6;Estrogen receptor modulator 6Estrogen receptor modulator 6

    Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for ERβ over ERα, as evidenced by its affinity (K i = 8.4 nM).

    价 格:¥电议型 号:T40893产 地:中国大陆

  • T40323EZH2-IN-6EZH2-IN-6EZH2-IN-6

    EZH2-IN-6 is an EZH2 inhibitor with enhanced antitumor activity.

    价 格:¥电议型 号:T40323产 地:中国大陆

  • T39972EB-42486;化合物EB-42486EB-42486

    EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.

    价 格:¥电议型 号:T39972产 地:中国大陆

  • T38787ER176;ER176ER176

    ER176 is a novel PET radioligand utilized for the visualization of 18 kDa translocator protein (TSPO), a neuroinflammation biomarker, marking the advancement in imaging technology.

    价 格:¥电议型 号:T38787产 地:中国大陆

  • T37176Edoxaban impurity 6;Edoxaban impurity 6Edoxaban impurity 6

    Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2].

    价 格:¥电议型 号:T37176产 地:中国大陆

  • T35915Erlotinib-13C6;Erlotinib-13C6Erlotinib-13C6;Erlotinib-13C6

    Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].

    价 格:¥电议型 号:T35915产 地:中国大陆

  • T35913EMI56;EMI56EMI56

    EMI56, a derivative of EMI1, exhibits enhanced potency against mutant EGFR compared to EMI1. Additionally, EMI56 effectively inhibits EGFR triple mutants[1].

    价 格:¥电议型 号:T35913产 地:中国大陆

  • T34876Ticarbodine;化合物 T34876EL-974|||EL 974|||EL974;EL-974|||EL 974|||EL974

    Ticarbodine(EL-974)is an Anthelmintic agent.

    价 格:¥电议型 号:T34876产 地:中国大陆

  • T3458EED226;化合物EED226EED226

    EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.

    价 格:¥电议型 号:T3458产 地:中国大陆

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