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T22756EB-47 dihydrochloride化合物 T22756EB 47
EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).
价 格:¥电议型 号:T22756产 地:中国大陆
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T21316Apaziquone;化合物 T21316EO-9|||NSC382459|||EO9|||NSC 382459|||EO 9|||NSC-382459;EO-9|||NSC382459|||EO9|
Apaziquone has potential antineoplastic and radiosensitization activities. It is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death.
价 格:¥电议型 号:T21316产 地:中国大陆
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T20006Isopropyl palmitate;化合物 T20006EINECS 205-571-1|||Isopropyl hexadecanoate|||BRN 1786567|||AI3-05733||
Isopropyl palmitate is the isopropyl alcohol and palmitic acid ester. It is a moisturizer, emollient, anti-static agent, and thickening agent.
价 格:¥电议型 号:T20006产 地:中国大陆
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T19776Equilenin;化合物 T19776Equilenine|||E 400|||NSC 9901|||d-Equilenin;Equilenine|||E 400|||NSC 9901|||d-Eq
Equilenin is an equine estrogen found in the urine of pregnant mares. It is also a naturally fluorescent steroid, has a high binding affinity for human sex steroid-binding protein (SBP).
价 格:¥电议型 号:T19776产 地:中国大陆
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T19089(Z)-Viaminate化合物 (Z)-ViaminateEthyl 4-((2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-
(Z)-Viaminate is a derivative of Retinoic acid.
价 格:¥电议型 号:T19089产 地:中国大陆
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T18826Thalidomide-O-PEG2-propargyl;化合物 T18826E3 ligase Ligand-Linker Conjugates 32;E3 ligase Ligand-Linker
Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1].
价 格:¥电议型 号:T18826产 地:中国大陆
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T17936endo-BCN-PEG3-NH2;化合物 T17936endo-BCN-PEG3-NH2
endo-BCN-PEG3-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17936产 地:中国大陆
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T17906Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc;化合物 T17906E3 Ligase Ligand-Linker Conjugates 53|||Cereblo
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a novel synthesized conjugate compound functioning as an E3 ligase ligand-linker in PROTAC technology. This compound incorporates a Pomalidomide-derived cereblon ligand, which binds selectively to the E3 ligase cereblon, and a 2-unit PEG linker, which provides stability and flexibility to the conjugate.
价 格:¥电议型 号:T17906产 地:中国大陆
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T17896cIAP1 Ligand-Linker Conjugates 4;化合物 T17896E3 ligase Ligand-Linker Conjugates 42;E3 ligase Ligand-Li
cIAP1 Ligand-Linker Conjugates 4 is a chemical compound that comprises an IAP ligand specifically designed for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 4, has the potential to be utilized in the development of SNIPERs[1].
价 格:¥电议型 号:T17896产 地:中国大陆
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T17886cIAP1 Ligand-Linker Conjugates 15 hydrochloride;化合物 T17886E3 ligase Ligand-Linker Conjugates 34 hydr
cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is useful in the development of SNIPERs[1].
价 格:¥电议型 号:T17886产 地:中国大陆
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T17876E3 ligase Ligand 18;化合物 T17876E3 ligase Ligand 18
E3 ligase Ligand 18 is a ligand that binds to E3 ubiquitin ligase, and it can be chemically attached to a protein ligand through a linker to create PROTACs. The resulting PROTACs function as inducers of ubiquitination-mediated degradation, targeting cancer-promoting proteins[1].
价 格:¥电议型 号:T17876产 地:中国大陆
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T17296Zotatifin;化合物 T17296eFT226;eFT226
Zotatifin is a potent and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM). Zotatifin effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis (IC90=37 nM).
价 格:¥电议型 号:T17296产 地:中国大陆
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T15256Etofylline clofibrate;化合物 T15256Etofylline clofibrate
Etofylline clofibrate has a hypolipidemic and antithrombotic effect and it also has an agonistic interaction with intimal PGI2.
价 格:¥电议型 号:T15256产 地:中国大陆
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T15250ETC-206;化合物ETC-206ETC-206
ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM).
价 格:¥电议型 号:T15250产 地:中国大陆
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T15226endo-BCN-PEG4-acid;化合物 T15226endo-BCN-PEG4-acid
endo-BCN-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15226产 地:中国大陆
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T14829Bromoenol lactone;化合物 T14829(6E)-Bromoenol lactone;(6E)-Bromoenol lactone
Bromoenol lactone is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2β; IC50: ~7 μM). It inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx.
价 格:¥电议型 号:T14829产 地:中国大陆
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T125258(4E,6E,12E)-Tetradecatriene -8,10-diyne-1,3-diol diacetate;化合物 (4E,6E,12E)-Tetradecatriene -8,10-diy
(4E,6E,12E)-Tetradecatriene -8,10-diyne-1,3-diol diacetate is a useful organic compound for research related to life sciences and the catalog number is T125258.
价 格:¥电议型 号:T125258产 地:中国大陆
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T12486Piribedil D8;化合物 T12486ET-495 D8;ET-495 D8
Piribedil D8 is the deuterium labeled Piribedil, which is an agent of antiparkinsonian.
价 格:¥电议型 号:T12486产 地:中国大陆
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T11226ERK1/2 inhibitor 1;化合物 T11226ERK1/2 inhibitor 1
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.
价 格:¥电议型 号:T11226产 地:中国大陆
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T11216Eplivanserin (mixture)化合物 T11216Eplivanserin mixture|||SR-46349 (mixture)
Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist,
价 格:¥电议型 号:T11216产 地:中国大陆