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  • T16847SA 47SA 47

    SA 47 is a selective and effective inhibitor of fatty acid amide hydrolase and carbamate.

    价 格：￥电议型 号：T16847产 地：美洲

  • T1774SB 742457SB 742457,GSK-742457,RVT-101

    SB742457 is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer´s Disease.

    价 格：￥电议型 号：T1774产 地：美洲

  • T1904SGI-1027SGI-1027,SGI1027,SGI 1027

    SGI-1027 is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027 against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively.

    价 格：￥电议型 号：T1904产 地：美洲

  • T2708SL-327SL-327,SL327,SL 327

    SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.

    价 格：￥电议型 号：T2708产 地：美洲

  • T4670SR0987SR0987

    SR0987 is a RORγt agonist,

    价 格：￥电议型 号：T4670产 地：美洲

  • T5406SNAP-94847SNAP-94847

    SNAP-94847 is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces food intake in mice.

    价 格：￥电议型 号：T5406产 地：美洲

  • T5631SIS17SIS17

    SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.

    价 格：￥电议型 号：T5631产 地：美洲

  • T6140SB-334867SB-334867,SB334867,SB 334867

    SB-334867 is a selective orexin-1 (OX1) receptor antagonist.

    价 格：￥电议型 号：T6140产 地：美洲

  • T83891Sulfonadyn-47；化合物 Sulfonadyn-47Sulfonadyn-47

    Sulfonadyn-47 is a dynamin inhibitor that effectively inhibits dynamin GTPase activity with an IC50 of 3.5 ?M in cell-free assays. Additionally, it disrupts clathrin-mediated endocytosis in U2OS cells (IC50 = 27.3 ?M) and impedes the depolarization-stimulated uptake of the synaptic vesicle endocytosis (SVE) marker FM4-64 in isolated rat brain synaptosomes (IC50 = 12.3 ?M). Significantly, in vivo administration of sulfonadyn-47 at doses of 30 and 60 mg/kg demonstrates anticonvulsant properties in

    价 格：￥电议型 号：T83891产 地：中国大陆

  • T81204SARS-CoV-2-IN-67；化合物 SARS-CoV-2-IN-67SARS-CoV-2-IN-67

    SARS-CoV-2-IN-67 (Compound 16), a derivative of vitamin K, exhibits anti-SARS-CoV-2 properties, with an effective concentration (EC50) of 64.8 μM in VeroE6/TMPRSS2 cells, and inhibits SARS-CoV-2 RdRp activity [1].

    价 格：￥电议型 号：T81204产 地：中国大陆

  • T81165SHP2-IN-17；化合物 SHP2-IN-17SHP2-IN-17

    SHP2-IN-17 (compound 192) is a potent inhibitor of SHP2, exhibiting an IC50 of 2 nM and holds potential for use in glioblastoma research [1].

    价 格：￥电议型 号：T81165产 地：中国大陆

  • T81152SKF 81297；化合物 SKF 81297SKF 81297

    SKF 81297 is a selective and potent agonist for the dopamine D1 receptor [1].

    价 格：￥电议型 号：T81152产 地：中国大陆

  • T81089Steroid sulfatase-IN-7；化合物 Steroid sulfatase-IN-7Steroid sulfatase-IN-7

    Steroid sulfatase-IN-7 is an irreversible inhibitor of steroid sulfatase (STS), demonstrating potent activity with an IC50 of 0.05 nM against human placental STS, rendering it suitable for application in cancer research [1].

    价 格：￥电议型 号：T81089产 地：中国大陆

  • T81082STING-IN-7；化合物 STING-IN-7STING-IN-7

    STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of 11.5 nM. It effectively hampers the phosphorylation of both STING and interferon regulatory factor 3 (IRF3) [1].

    价 格：￥电议型 号：T81082产 地：中国大陆

  • T79660SARS-CoV-2 3CLpro-IN-17；化合物 SARS-CoV-2 3CLpro-IN-17SARS-CoV-2 3CLpro-IN-17

    Compound 3h, also known as SARS-CoV-2 3CLpro-IN-17, is a selective inhibitor of the SARS-CoV-2 3CL protease, demonstrating an IC50 of 0.322 μM [1].

    价 格：￥电议型 号：T79660产 地：中国大陆

  • T79356SARS-CoV-2-IN-57；化合物 SARS-CoV-2-IN-57SARS-CoV-2-IN-57

    SARS-CoV-2-IN-57 (compound (+)-R-26) is a potent inhibitor of SARS-CoV-2 with an IC50 of 80 nM and demonstrates high affinity for the Sigma Receptor, exhibiting Kis of 13.6 nM (S1R) and 14.4 nM (S2R) [1].

    价 格：￥电议型 号：T79356产 地：中国大陆

  • T79278SARS-CoV-2 Mpro-IN-7；化合物 SARS-CoV-2 Mpro-IN-7SARS-CoV-2 Mpro-IN-7

    SARS-CoV-2 Mpro-IN-7 (compound 6g) effectively inhibits SARS-CoV-2 main protease (Mpro) with an IC50 value of 8.8 μM and exhibits a cytotoxic concentration (CC50) of 10 μM [1].

    价 格：￥电议型 号：T79278产 地：中国大陆

  • T78943Syk-IN-7；化合物 Syk-IN-7Syk-IN-7

    Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].

    价 格：￥电议型 号：T78943产 地：中国大陆

  • T78890SDH-IN-7；化合物 SDH-IN-7SDH-IN-7

    SDH-IN-7 (compound G28) is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 26 nM against porcine SDH and possesses fungicidal properties [1].

    价 格：￥电议型 号：T78890产 地：中国大陆

  • T78803SIRT5 inhibitor 7；化合物 SIRT5 inhibitor 7SIRT5 inhibitor 7

    SIRT5 inhibitor 7 (compound 58), a selective and substrate-competitive SIRT5 inhibitor, exhibits anti-inflammatory properties by modulating protein succinylation and attenuating pro-inflammatory cytokine release. It demonstrates renal protective effects and is active in vivo, showing efficacy in AKI mouse models subjected to lipopolysaccharide (LPS) and cecal ligation/perforation (CLP)-induced sepsis-related acute kidney injury [1].

    价 格：￥电议型 号：T78803产 地：中国大陆

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