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T63610SPR7；化合物 SPR7SPR7
SPR7 is a potent and selective rhodesain inhibitor (Ki: 0.51 nM). SPR7 exhibited antiparasitic effects against T. b. brucei (EC50: 1.65 μM).
价 格：￥电议型 号：T63610产 地：中国大陆
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T62923SOS1-IN-7；化合物 SOS1-IN-7SOS1-IN-7
SOS1-IN-7 (compound 18-p1) is a potent inhibitor of SOS1 and acts on SOS1-G12D (IC50: 20 nM) and SOS1-G12V (IC50: 67 nM).
价 格：￥电议型 号：T62923产 地：中国大陆
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T62618SPH3127；化合物 SPH3127SPH3127
SPH3127 (DRI 18) is a potent, orally active, novel direct renin inhibitor with IC50 values of 0.4 nM and 0.45 nM for recombinant human-renin and human plasma renin activity, respectively. SPH3127 has an anti-hypertensive effect and can be used to study hypertension.
价 格：￥电议型 号：T62618产 地：中国大陆
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T62321ST247；化合物 ST247ST247
ST247 is a potent PPARβ/δ inverse agonist with a high affinity for PPARβ/δ and is able to inversely regulate the expression of the activation marker CCL2. ST247 inhibits agonist-induced transcriptional activity of PPARβ/δ. ST247 efficiently induces interaction with co-repressors.
价 格：￥电议型 号：T62321产 地：中国大陆
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T62290SKLB-197；化合物 SKLB-197SKLB-197
SKLB-197 is able to act on ATR (IC50: 0.013 μM), but has little or no activity on the other 402 protein kinases. In vitro and in vivo, SKLB-197 has shown significant antitumour effects against ATM-deficient tumours.
价 格：￥电议型 号：T62290产 地：中国大陆
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T61787SYN20028567；化合物 SYN20028567SYN20028567
SYN20028567, an aromatase (CYP19) inhibitor, exhibits an IC50 value of 9.4 nM. It has potential applications in breast cancer research [1].
价 格：￥电议型 号：T61787产 地：中国大陆
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T61666SUN13837；化合物 SUN13837SUN13837
SUN13837 is an orally active, potent modulator of the fibroblast growth factor receptor (FGFR) with the ability to penetrate the blood-brain barrier (BBB). It exhibits neuroprotective activity and holds promise for furthering research on neurodegenerative diseases [1].
价 格：￥电议型 号：T61666产 地：中国大陆
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T61613SARS-CoV-2-IN-17；化合物 SARS-CoV-2-IN-17SARS-CoV-2-IN-17
SARS-CoV-2-IN-17 (Compound 16) is a highly effective inhibitor of SARS-CoV-2 nucleocapsid protein (NPro). It demonstrates potent anti-viral activity, with an EC50 value of 2.18 μM. Furthermore, SARS-CoV-2-IN-17 binds to NPro with a low Kd value of 7.82 μM, highlighting its potency as a NPro ligand [1].
价 格：￥电议型 号：T61613产 地：中国大陆
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T6140SB-334867 free base；化合物SB-334867SB334867A free base|||SB-334867|||SB 334867|||SB334867；SB334867A fre
SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.
价 格：￥电议型 号：T6140产 地：中国大陆
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T61063SEN177；化合物 SEN177SEN177
SEN177 shows the potential in the research of Huntington’s disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].
价 格：￥电议型 号：T61063产 地：中国大陆
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T61043STING agonist-7；化合物 STING agonist-7STING agonist-7
STING agonist-7 is an agonist of non-nucleotide STING that binds selectively to mouse STING but not human STING [1].
价 格：￥电议型 号：T61043产 地：中国大陆
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T60358sEH inhibitor-7；化合物sEH inhibitor-7sEH inhibitor-7
sEH inhibitor-7 is a soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in human and mouse with IC 50 s of 6.2 μM and 0.15 μM, respectively. sEH inhibitor-7 is associated with anti-inflammatory active molecules.
价 格：￥电议型 号：T60358产 地：中国大陆
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T5631SIS17；化合物SIS17SIS17
SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.
价 格：￥电议型 号：T5631产 地：中国大陆
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T5455HT-2157；化合物HT-2157SNAP37889|||SNAP-37889；SNAP37889|||SNAP-37889
HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.
价 格：￥电议型 号：T5455产 地：中国大陆
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T5406SNAP 94847；化合物SNAP-94847SNAP-94847；SNAP-94847
SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces food intake in mice.
价 格：￥电议型 号：T5406产 地：中国大陆
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T4328OSS_128167；化合物OSS_128167SIRT6-IN-1；SIRT6-IN-1
OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 μM).
价 格：￥电议型 号：T4328产 地：中国大陆
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T4210SAR-20347；化合物SAR20347SAR20347；SAR20347
SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).
价 格：￥电议型 号：T4210产 地：中国大陆
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T40207SARS-CoV-2-IN-7；SARS-CoV-2-IN-7SARS-CoV-2-IN-7
SARS-CoV-2-IN-7 demonstrates potent inhibition of viral replication in SARS-CoV-2-infected Vero E6 cells with an IC50 value of 844 nM.
价 格：￥电议型 号：T40207产 地：中国大陆
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T39799S2157；S2157S2157；S2157
S2157, a potent N-alkylated tranylcypromine (TCP) derivative lysine-specific demethylase 1 (LSD1) inhibitor, enhances H3K9 methylation and concurrently reduces H3K27 acetylation at super-enhancer sites. This compound triggers apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by inhibiting NOTCH3 and TAL1 gene expression. Moreover, S2157 is capable of crossing the blood-brain barrier, effectively eliminating central nervous system (CNS) leukemia in mice models implanted
价 格：￥电议型 号：T39799产 地：中国大陆
