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T4118SB 271046 hydrochlorideoral,test,Serotonin Receptor,SB271046,5-HT Receptor,Inhibitor,inhibit,5-hydro
SB 271046 hydrochloride is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and < 4.99 at 5-HT1B, 5-HT1F, α1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is > 200-fold selective over 55 other receptors, enzymes and ion channels. It increases extracellular aspartate and glutamate in the frontal cortex and exhibits anticonvulsant activity (EC50:
价 格:¥电议型 号:T4118产 地:中国大陆
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T16856SB228357SB-228357,SB228357
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
价 格:¥电议型 号:T16856产 地:中国大陆
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T25209CB29CB29
CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).
价 格:¥电议型 号:T25209产 地:中国大陆
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T22009CB2 receptor agonist 2
CB2 receptor agonist 2 is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor, Ki = 8.5 nM. CB2 receptor agonist 2 has high affinity and selectivity for CB2.
价 格:¥电议型 号:T22009产 地:中国大陆
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T67745CB2R/FAAH?modulator-2CB2R/FAAH?modulator2
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 has studies research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
价 格:¥电议型 号:T67745产 地:中国大陆
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TN2268TetrahydromagnololMagnolignan,metabolite,Inhibitor,inhibit,Tetrahydromagnolol,Magnolol,CB2,GPR55,Can
Tetrahydromagnolol can activate cannabinoid (CB) receptors.
价 格:¥电议型 号:TN2268产 地:中国大陆
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T6103VS-5584VS5584;VS 5584;SB2343
VS-5584 is a pan-PI3K/mTOR kinase inhibitor.
价 格:¥电议型 号:T6103产 地:中国大陆
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T5360Eprotirome伊罗替罗;KB2115
Eprotirome, a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.
价 格:¥电议型 号:T5360产 地:中国大陆
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T4674SB297006SB 297006
SB 297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of other chemokine receptors. SB 2970
价 格:¥电议型 号:T4674产 地:中国大陆
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T4260Capmatinib 2HClINCB28060盐酸盐;INCB28060 2HCl;INC-280 2HCl
INCB-28060(free base) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.INCB28060 exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-fold selectivity over a large panel of human kinas
价 格:¥电议型 号:T4260产 地:中国大陆
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T4078SB 242235SB-242235;SB242235
SB-242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.
价 格:¥电议型 号:T4078产 地:中国大陆
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T3919Ginsenoside Rb2人参皂苷 Rb2;人参皂苷Rb2;Ginsenoside C
Ginsenoside Rb2 found in species of Panax, upregulating GPR120 gene expression.
价 格:¥电议型 号:T3919产 地:中国大陆
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T3810Saikosaponin B2柴胡皂苷 B2;柴胡皂甙 B2
Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with potentiation of expressions of tyr
价 格:¥电议型 号:T3810产 地:中国大陆
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T3077SB 216763SB216763
SB216763 is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).
价 格:¥电议型 号:T3077产 地:中国大陆
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T2932Ginsenoside Rh1人参皂苷 Rh1;人参皂苷Rh1;Sanchinoside B2;Prosapogenin A2;Sanchinoside Rh1;20(S)-Ginsenoside R
Ginsenoside Rg1, one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
价 格:¥电议型 号:T2932产 地:中国大陆
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T2872Ginsenoside Re人参皂苷 Re;人参皂苷Re;Sanchinoside Re;Ginsenoside B2;Chikusetsusaponin Ivc;Panaxoside Re
Ginsenoside Re may have properties that inhibit or prevent the growth of tumors.
价 格:¥电议型 号:T2872产 地:中国大陆
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T28167NGB 2904NGB2904;NGB2904 HCl;NGB-2904
NGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by qui
价 格:¥电议型 号:T28167产 地:中国大陆
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T2370AC-55541AOB2796
AOB2796 is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.
价 格:¥电议型 号:T2370产 地:中国大陆
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T2301SB 202190FHPI;SB202190
SB 202190 is a selective and cell-permeable inhibitor of p38 MAPK (IC50s: 50/100 nM for p38α/p38β).
价 格:¥电议型 号:T2301产 地:中国大陆
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T22595B2奥司他韦杂质B(2-叠氮杂合物);Linazolamide intermediate B impurity 2;CPNQ;5-[4-(4-Chlorobenzoyl)-1-piperazinyl]
B2 promotes inclusion formation in cellular models of Huntington´s disease and Parkinson´s disease
价 格:¥电议型 号:T22595产 地:中国大陆