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产品数:86101
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T7949NCC007inhibit,NCC-007,Inhibitor,NCC007,NCC 007,Casein Kinase
NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.
价 格:¥电议型 号:T7949产 地:中国大陆
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T7568LM22A-4LM-22A-4,Inhibitor,Trk Receptor,inhibit,LM22A4,LM22A-4,Tropomyosin related kinase receptor,LM
LM22A-4 is a brain-derived neurotrophic factor (BDNF) mimetic and agonist of the receptor tropomyosin-related kinase B (TrkB; IC50 : 47 nM in a fluorescence anisotropy assay)
价 格:¥电议型 号:T7568产 地:中国大陆
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T6845GNE-317inhibit,GNE-317,Inhibitor,Phosphoinositide 3-kinase,Mammalian target of Rapamycin,mTOR,GNE 31
GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).
价 格:¥电议型 号:T6845产 地:中国大陆
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T6630Quercetin DihydrateInhibitor,PI3K,Phosphoinositide 3-kinase,Quercetin Dihydrate,Apoptosis,inhibit
Quercetin is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and anticancer effects.
价 格:¥电议型 号:T6630产 地:中国大陆
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T9123DS-1205TRKA,c-Met/HGFR,migration,Axl,Tyro3,Trk Receptor,MET,DS 1205,Mer,Tropomyosin related kinase r
DS-1205 is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205 also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205 can inhibit cell migration in vitro and tumor growth in vivo[1].
价 格:¥电议型 号:T9123产 地:中国大陆
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TN1673Garcinone CCyclin dependent kinase,inhibit,Garcinone C,STAT,ATM/ATR,CDK,ATM and RAD3 related,Inhibit
Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effects on certain cancers.
价 格:¥电议型 号:TN1673产 地:中国大陆
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T6866AUZ 454AUZ454,ACHN,Caki-1,cells,K 03861,K-03861,Cyclin dependent kinase,AUZ-454,AUZ 454,Inhibitor,in
K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.
价 格:¥电议型 号:T6866产 地:中国大陆
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T7200TAK-960Polo-like Kinase (PLK),cell,cancer,proliferation,Inhibitor,mitosis,TAK960,TAK 960,leukemia,in
TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.
价 格:¥电议型 号:T7200产 地:中国大陆
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T6435CCT129202inhibit,CCT-129202,CCT 129202,Inhibitor,CCT129202,Aurora Kinase
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.
价 格:¥电议型 号:T6435产 地:中国大陆
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T8461SKI VPI3K,SKI V,Inhibitor,Apoptosis,GST-hSK,sphingosine,second,mitogenic,Phosphoinositide 3-kinase,S
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces apoptosis and has antitumor activity
价 格:¥电议型 号:T8461产 地:中国大陆
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T6940PHA-767491 hydrochloridePHA767491,PHA 767491,inhibit,CAY-10572,Cyclin dependent kinase,CDK,CAY 10572
PHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.
价 格:¥电议型 号:T6940产 地:中国大陆
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TQ0010Brepocitinibinhibit,Janus kinase,PF06700841,JAK,Brepocitinib,Inhibitor,PF 06700841
Brepocitinib is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).
价 格:¥电议型 号:TQ0010产 地:中国大陆
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T6920ON123300Platelet-derived growth factor receptor,AMP-activated protein kinase,ON-123300,ON 123300,FGF
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).
价 格:¥电议型 号:T6920产 地:中国大陆
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TQ0048BI-882370BI-882370,Raf,BI882370,inhibit,Inhibitor,Raf kinases,BI 882370
BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic BRAFV600E-mutant, the WT BRAF and CRAF kinases (IC50s: 0.4, 0.8 and 0.6 nM). BI-882370 also inhibits SRC family kinases.
价 格:¥电议型 号:TQ0048产 地:中国大陆
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T6997SU6656PTK2 protein tyrosine kinase 2,Focal adhesion kinase,FAK,Akt,SU-6656,PTK2,Inhibitor,Protein ki
SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.
价 格:¥电议型 号:T6997产 地:中国大陆
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TN1410Asperulosidic acidERK,Inhibitor,Nuclear factor-κB,Extracellular signal regulated kinases,NF-κB,Nucle
Asperulosidic acid has anti-tumor, anti-oxidant, and anti-inflammatory activities.ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways.
价 格:¥电议型 号:TN1410产 地:中国大陆
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T6756AMG 925CDK,AMG 925,Cluster of differentiation antigen 135,FLT3,Cyclin dependent kinase,inhibit,CD135
AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.
价 格:¥电议型 号:T6756产 地:中国大陆
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T7912(?)-MyrtenalAkt,hyperglycemia,terpene,inhibit,GLUT2,Protein kinase B,Inhibitor,diabetic,(?) Myrtenal
(1R)-( )-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
价 格:¥电议型 号:T7912产 地:中国大陆
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T7007UNC2025Inhibitor,inhibit,FLT3,leukemia,CD135,Fms like tyrosine kinase 3,acute,Cluster of differentia
UNC-2025( IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
价 格:¥电议型 号:T7007产 地:中国大陆
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TQ0009UCB9608Phosphatidylinositol 4 kinases,UCB-9608,Inhibitor,UCB 9608,UCB9608,PI4 kinases,PI4K,inhibit
UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases.
价 格:¥电议型 号:TQ0009产 地:中国大陆