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产品数:86101
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T8353Pamoic acidPamoic acid,GPR35,neuroprotective,Extracellular signal regulated kinases,Inhibitor,inhibi
Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
价 格:¥电议型 号:T8353产 地:中国大陆
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T73277-Methoxyisoflavone7-Methoxyisoflavone,inhibit,AMP-activated protein kinase,7Methoxyisoflavone,AMPK,
7-Methoxyisoflavone is an activator of adenosine monophosphate-activated protein kinase (AMPK).
价 格:¥电议型 号:T7327产 地:中国大陆
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TQ0137A-484954CaMK,Autophagy,Inhibitor,Calmodulin-dependent protein kinases,A-484954,A484954,inhibit,Calmo
A 484954 is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.
价 格:¥电议型 号:TQ0137产 地:中国大陆
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T7214TEPP-46TEPP46,TEPP 46,Pyruvate Kinase,ML 265,ML-265,Inhibitor,TEPP-46,inhibit
ML265 is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1, PKL and PKR,induces tetramerization and reduces tumor formation and size in a mouse xenograft model. .
价 格:¥电议型 号:T7214产 地:中国大陆
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T6882LY3009120Raf kinases,DP 4978,inhibit,LY-3009120,DP4978,Autophagy,LY3009120,Raf,LY 3009120,Inhibitor
LY03009120 is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1.
价 格:¥电议型 号:T6882产 地:中国大陆
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T9229Pim-1/2 kinase inhibitor 12,4 Thiazolidinedione, 5 p methoxybenzylidene ,2,4Thiazolidinedione, 5pmet
Pim-1/2 kinase inhibitor 1 is an orally active pim-1/2 kinase inhibitor. Pim-1/2 kinase inhibitor 1 blocks the ability of Pim kinases to phosphorylate peptides, and inhibits the pim protein kinase directed phosphorylation of 4E-BP1 and p27 Kip1. Pim-1/2 kinase inhibitor 1 can be used in the cancer research, especially prostate cancer [1].
价 格:¥电议型 号:T9229产 地:中国大陆
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TN1136Procyanidin A1Inhibitor,Proanthocyanidin A 1,Procyanidin A1,Procyanidin A 1,Protein kinase C,inhibit
Procyanidin A1 has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an internal store in RBL-2H3 cells.
价 格:¥电议型 号:TN1136产 地:中国大陆
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T6757AMG319AMG-319,AMG 319,Inhibitor,inhibit,PI3K,AMG319,Phosphoinositide 3-kinase
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.
价 格:¥电议型 号:T6757产 地:中国大陆
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T8362Benzamidine hydrochlorideurokinase-type ,plasminogen,Threonine proteases,activator,inhibit,factor Xa
Benzamidine HCl is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).
价 格:¥电议型 号:T8362产 地:中国大陆
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T6525GW 5074inhibit,GW-5074,Raf,Apoptosis,GW 5074,Inhibitor,Raf kinases
GW5074(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms.
价 格:¥电议型 号:T6525产 地:中国大陆
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T8546BD750Immunosuppressant,JAK,BD750,cell,Janus kinase,BD-750,inhibit,STAT,Inhibitor,BD 750
BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in mouse and human T cells, respectively)
价 格:¥电议型 号:T8546产 地:中国大陆
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TN1499Cimiracemoside CAMP-activated protein kinase,inhibit,Inhibitor,Cimiracemoside C,AMPK
Cimiracemoside C is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.
价 格:¥电议型 号:TN1499产 地:中国大陆
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T6852GSK481GSK481,inhibit,Inhibitor,RIPK,GSK-481,RIP kinase,GSK 481,Receptor-interacting protein kinases
GSK481 is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.
价 格:¥电议型 号:T6852产 地:中国大陆
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T9564IRE1α kinase-IN-1endoribonuclease,Inositol requiring enzyme 1,cells,IRE1,oligomerization,IRE-1α kina
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosphorylation, and also inhibits IRE1α RNase activity (IC50=80 nM)
价 格:¥电议型 号:T9564产 地:中国大陆
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T8969API-1TRAIL,API 1,PKB,Akt,Inhibitor,API-1,inhibit,Akt/PKB inhibitor,Protein kinase B,API1,Apoptosis
API-1 is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .
价 格:¥电议型 号:T8969产 地:中国大陆
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T9305Necroptosis-IN-1NecroptosisIN1,RIP kinase,Inhibitor,inhibit,Necroptosis,RIPK,Necroptosis IN 1,Recept
Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.
价 格:¥电议型 号:T9305产 地:中国大陆
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T11492GSK2983559 free acidinhibit,THP-1 cell,RIP kinase,GSK 2983559,GSK2983559 free acid,Inhibitor,GSK-298
GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammatory bowel disease explant samples an
价 格:¥电议型 号:T11492产 地:中国大陆
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T7190ActeinJNK,Akt,Actein,Apoptosis,PKB,Autophagy,Inhibitor,inhibit,Protein kinase B
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein´s ability to pathways involved in lipid disorders and carcinogenesis may make it a new agent for preventing and treating these major disorders, it has been shown to inhibit the proliferation of human breast cancer cells, by altering the activity of the ER IP3 receptor and Na,K-ATPase, inducing cal
价 格:¥电议型 号:T7190产 地:中国大陆
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T6899MRT68921MRT 68921,ULK,Unc-51 like kinase,MRT68921,MRT-68921,Inhibitor,inhibit
MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.
价 格:¥电议型 号:T6899产 地:中国大陆
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T19783DehydroabiethylaminePyruvate dehydrogenase kinase,PDH kinase,Dehydroabiethylamine,Inhibitor,PDHK,Can
Dehydroabiethylamine is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity.
价 格:¥电议型 号:T19783产 地:中国大陆