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T2618LGK974LGK 974；WNT974；LGK-974；NVP-LGK974
LGK-974 is an effective and selective PORCN inhibitor and inhibits Wnt signaling (IC50: 0.4 nM) in TM3 cells. It has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
价 格：￥电议型 号：T2618产 地：中国大陆
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T2383Panobinostat帕比司他；NVP-LBH589；LBH589
Panobinostat is a potent inhibitor of all HDACs (Kis: 0.6-31 nM for HDAC1-11).
价 格：￥电议型 号：T2383产 地：中国大陆
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T2251NVP-TAE 684TAE684；5-氯-N2-[2-甲氧基-4-[4-(4-甲基-1-哌嗪基)-1-哌啶基]苯基]-N4-[2-[(1-甲基乙基)磺酰基]苯基]-2,4-嘧啶二胺
NVP-TAE 684 is a excellently effective and specific ALK inhibitor(IC50=3 nM).
价 格：￥电议型 号：T2251产 地：中国大陆
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T2235DactolisibNVP-BEZ235；BEZ235；2-甲基-2-[4-[3-甲基-2-氧代-8-(喹啉-3-基)-2,3-二氢咪唑并[4,5-c]喹啉-1-基]苯基]丙腈
Dactolisib is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).
价 格：￥电议型 号：T2235产 地：中国大陆
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T2116AEE788NVP-AEE 788
AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
价 格：￥电议型 号：T2116产 地：中国大陆
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T2114VER-82576NVP-BEP800
NVP-BEP800, a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.
价 格：￥电议型 号：T2114产 地：中国大陆
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T1989LuminespibAUY922；NVP-AUY922；VER-52296
AUY922 (NVP-AUY922) is a new-type inhibitor of HSP90 (IC50s: 7.8/21 nM for HSP90α/β in cell free assay).
价 格：￥电议型 号：T1989产 地：中国大陆
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T1975InfigratinibBGJ-398；NVP-BGJ398
Infigratinib (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.
价 格：￥电议型 号：T1975产 地：中国大陆
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T1963CapmatinibINCB28060；NVP-INC280；INC-280；卡马替尼
Capmatinib is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.
价 格：￥电议型 号：T1963产 地：中国大陆
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T19487NVP-BHG712 isomer
NVP-BHG712 isomer shows conserved non-bonded binding to EPHA2 and EPHB4.
价 格：￥电议型 号：T19487产 地：中国大陆
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T1933NVP 231
NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.
价 格：￥电议型 号：T1933产 地：中国大陆
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T1926SonidegibNVP-LDE225；Erismodegib；LDE225
LDE225 (NVP-LDE225; Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
价 格：￥电议型 号：T1926产 地：中国大陆
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T1918NVP-TAE 226TAE226
NVP-TAE226 is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC50: 3.5 nM); 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK.
价 格：￥电议型 号：T1918产 地：中国大陆
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T1878XAV-939NVP-XAV939；XAV939；XAV 939
XAV-939 shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM in cell-free assays).
价 格：￥电议型 号：T1878产 地：中国大陆
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T1827Buparlisib布帕尼西；BKM120；NVP-BKM120
Buparlisib is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).
价 格：￥电议型 号：T1827产 地：中国大陆
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T16363NVP-2
NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC5
价 格：￥电议型 号：T16363产 地：中国大陆
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T1595Nevirapine奈韦拉平；奈伟拉平；BI-RG 587；NVP；NSC 641530
Nevirapine is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and
价 格：￥电议型 号：T1595产 地：中国大陆
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T15727Sonidegib diphosphateErismodegib diphosphate；NVP-LDE 225 diphosphate；LDE225 diphosphate
Erismodegib diphosphate is an effective and selective Smo antagonist (IC50: 1.3 nM and 2.5 nM for mouse and human Smo in a binding assay, respectively).
价 格：￥电议型 号：T15727产 地：中国大陆
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T1502Vildagliptin维达列汀；维格列汀；LAF237；NVP-LAF 237
Vildagliptin is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin´s cyano moiety undergoes hydrolysis and this inactive metabolite is excreted mainly via the urine.
价 格：￥电议型 号：T1502产 地：中国大陆
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T11838LEQ506NVP-LEQ506
LEQ506 is a second-generation smoothened (Smo) inhibitor with IC50s of 4 and 2 nM in mouse and human, respectively.
价 格：￥电议型 号：T11838产 地：中国大陆
