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T28221NVP-QAV-680;化合物 T28221NVPQAV680|||NVP-QAV 680|||NVP-QAV680|||NVP-QAV680|||NVP QAV 680|||QAV690 free
NVP-QAV-680 is a potent and selective antagonist of CRTh2 receptor. NVP-QAV-680 has nM functional potency for inhibition of CRTh2 driven human eosinophil and Th2 lymphocyte activation in vitro.
价 格:¥电议型 号:T28221产 地:中国大陆
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T27802LBM-415;化合物 T27802NVP-PDF-713;NVP-PDF-713
LBM-415 is a peptide deformylase (PDF) inhibitor.
价 格:¥电议型 号:T27802产 地:中国大陆
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T2680NVP-BVU972;化合物NVP-BVU972NVP-BVU972
NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.
价 格:¥电议型 号:T2680产 地:中国大陆
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T26685AUY954 HCl;化合物 T26685NVP-AUY954|||AUY 954|||AUY954 hydrochloride|||AUY-954|||AUY954;NVP-AUY954|||AUY
AUY-954 is a potent and selective S1P(1) modulator. AUY-954 prevents experimental autoimmune neuritis in rats.
价 格:¥电议型 号:T26685产 地:中国大陆
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T26225SRA880 malonate;化合物 T26225SRA880|||NVPSRA880|||NVP-SRA880|||NVP-SRA-880|||NVP-SRA 880|||NVP SRA880;S
SRA880 is a non-peptide somatostatin sst(1) receptor antagonist which displays a significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d)= 6.0) or a wide range of neurotransmitter receptors, except for the human dopamine D4 receptors. SRA880 positively modulates the release of endogenous SRIF, was found to synergize with imipramine in causing antidepressant-like effects in the tail suspension test.
价 格:¥电议型 号:T26225产 地:中国大陆
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T2618LGK974;化合物LGK-974LGK 974|||LGK-974|||NVP-LGK974|||WNT974;LGK 974|||LGK-974|||NVP-LGK974|||WNT974
LGK974 (NVP-LGK974) is an effective and selective PORCN inhibitor and inhibits Wnt signaling (IC50: 0.4 nM) in TM3 cells. It has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
价 格:¥电议型 号:T2618产 地:中国大陆
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T25895NVP-SAA164;化合物 T25895SAA 164|||SAA164|||SAA-164|||NVP SAA164;SAA 164|||SAA164|||SAA-164|||NVP SAA164
NVP-SAA164 is a nonpeptide bradykinin B1 receptor antagonist agent.
价 格:¥电议型 号:T25895产 地:中国大陆
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T25894NVP-AAD777;化合物 T25894AAD-777|||NVP-AAD-777|||NVP AAD 777;AAD-777|||NVP-AAD-777|||NVP AAD 777
NVP-AAD777 is a specific VEGFR-2 inhibitor.
价 格:¥电议型 号:T25894产 地:中国大陆
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T24564NVP-ABJ688;化合物 T24564ABJ-688|||ABJ 688|||ABJ688;ABJ-688|||ABJ 688|||ABJ688
NVP-ABJ688 is the cysteine protease cathepsin K inhibitor.
价 格:¥电议型 号:T24564产 地:中国大陆
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T2454Dacinostat;达西司特NVP-LAQ824|||LAQ824;NVP-LAQ824|||达西司特|||LAQ824
LAQ824 (Dacinostat (NVP-LAQ824)) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.
价 格:¥电议型 号:T2454产 地:中国大陆
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T2383Panobinostat;帕比司他NVP-LBH589|||LBH589;帕比司他|||NVP-LBH589|||LBH589
Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity. Panobinostat has antitumor activity and induces apoptosis and autophagy.
价 格:¥电议型 号:T2383产 地:中国大陆
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T2251NVP-TAE 684;化合物TAE684TAE684;TAE684|||5-氯-N2-[2-甲氧基-4-[4-(4-甲基-1-哌嗪基)-1-哌啶基]苯基]-N4-[2-[(1-甲基乙基)磺酰基]苯基
NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM).
价 格:¥电议型 号:T2251产 地:中国大陆
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T2235Dactolisib;化合物DactolisibBEZ235|||NVP-BEZ235;2-甲基-2-[4-[3-甲基-2-氧代-8-(喹啉-3-基)-2,3-二氢咪唑并[4,5-c]喹啉-1-基]苯
Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).
价 格:¥电议型 号:T2235产 地:中国大陆
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T21691NVP DPP 728 dihydrochloride;化合物 T21691NVP DPP 728 dihydrochloride
NVP-DPP728 is a potent, reversible, nitrile-dependent inhibitor of dipeptidyl peptidase IV (DPP-IV), demonstrating an inhibition constant (K i) of 11 nM for human DPP-IV amidolytic activity. By inhibiting the degradation of glucagon-like peptide-1 (GLP-1), NVP-DPP728 enhances insulin release following glucose intake, making it useful for diabetes research [1].
价 格:¥电议型 号:T21691产 地:中国大陆
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T2116AEE788;化合物AEE788NVP-AEE 788;NVP-AEE 788
AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
价 格:¥电议型 号:T2116产 地:中国大陆
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T2114VER-82576;化合物NVP-BEP800NVP-BEP800;NVP-BEP800
VER-82576 (NVP-BEP800), a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.
价 格:¥电议型 号:T2114产 地:中国大陆
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T1989Luminespib;化合物LuminespibAUY922|||VER-52296|||NVP-AUY922;AUY922|||VER-52296|||NVP-AUY922
Luminespib (VER-52296) is a new-type inhibitor of HSP90 (IC50s: 7.8/21 nM for HSP90α/β in cell free assay).
价 格:¥电议型 号:T1989产 地:中国大陆
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T1975Infigratinib;化合物InfigratinibBGJ-398|||NVP-BGJ398;BGJ-398|||NVP-BGJ398
Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.
价 格:¥电议型 号:T1975产 地:中国大陆
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T1963Capmatinib;卡马替尼NVP-INC280|||INC-280|||INCB28060;NVP-INC280|||INC-280|||卡马替尼|||INCB28060
Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.
价 格:¥电议型 号:T1963产 地:中国大陆
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T19487NVP-BHG712 isomer;化合物NVP-BHG712 isomerNVP-BHG712 isomer
NVP-BHG712 isomer shows conserved non-bonded binding to EPHA2 and EPHB4.
价 格:¥电议型 号:T19487产 地:中国大陆