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  • T11838LEQ506LEQ506,NVP-LEQ506,

    LEQ506 is a second-generation smoothened (Smo) inhibitor with IC50s of 4 and 2 nM in mouse and human, respectively.?

    价 格：￥电议型 号：T11838产 地：美洲

  • T12273NVP-CGM097 sulfateNVP-CGM097 sulfate,CGM097 sulfate,

    NVP-CGM097 sulfate is a potent and selective inhibitor of MDM2 (hMDM2, IC50 of 1.7±0.1 nM).

    价 格：￥电议型 号：T12273产 地：美洲

  • T12274Siremadlin R EnantiomerSiremadlin R Enantiomer,NVP-HDM201 R Enantiomer,HDM201 R Enantiomer

    Siremadlin R Enantiomer is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific inhibitor of MDM-2/p53.

    价 格：￥电议型 号：T12274产 地：美洲

  • T1502VildagliptinVildagliptin,NVP-LAF 237,LAF237

    Vildagliptin is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin´s cyano moiety undergoes hydrolysis and this inactive metabolite is excreted mainly via the urine.

    价 格：￥电议型 号：T1502产 地：美洲

  • T1595NevirapineNevirapine,NSC 641530,NVP

    Nevirapine is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and

    价 格：￥电议型 号：T1595产 地：美洲

  • T16363NVP-2NVP-2

    NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC5

    价 格：￥电议型 号：T16363产 地：美洲

  • T16364Infigratinib phosphateInfigratinib phosphate,BGJ-398 phosphate,NVP-BGJ398 phosphate

    Infigratinib phosphate is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).

    价 格：￥电议型 号：T16364产 地：美洲

  • T16365Buparlisib HydrochlorideBuparlisib Hydrochloride,BKM120 Hydrochloride,NVP-BKM120 Hydrochloride

    Buparlisib Hydrochloride is an inhibitor of pan-class I PI3K (IC50: 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively).

    价 格：￥电议型 号：T16365产 地：美洲

  • T1827BuparlisibBuparlisib,BKM120,NVP-BKM120

    Buparlisib is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).

    价 格：￥电议型 号：T1827产 地：美洲

  • T1918TAE226TAE226,NVP-TAE 226,

    NVP-TAE226 is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC50: 3.5 nM); 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK.

    价 格：￥电议型 号：T1918产 地：美洲

  • T1926SonidegibSonidegib,NVP-LDE225,Erismodegib

    LDE225 (NVP-LDE225; Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.

    价 格：￥电议型 号：T1926产 地：美洲

  • T1933NVP 231NVP 231

    NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.

    价 格：￥电议型 号：T1933产 地：美洲

  • T19487NVP-BHG712 isomerNVP-BHG712 isomer

    NVP-BHG712 isomer shows conserved non-bonded binding to EPHA2 and EPHB4.

    价 格：￥电议型 号：T19487产 地：美洲

  • T1975InfigratinibInfigratinib,NVP-BGJ398,BGJ-398

    Infigratinib (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.

    价 格：￥电议型 号：T1975产 地：美洲

  • T2114NVP-BEP800NVP-BEP800,VER-82576,

    NVP-BEP800, a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.

    价 格：￥电议型 号：T2114产 地：美洲

  • T2116AEE788AEE788,NVP-AEE 788,

    AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.

    价 格：￥电议型 号：T2116产 地：美洲

  • T2235DactolisibDactolisib,NVP-BEZ235,BEZ235

    Dactolisib is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).

    价 格：￥电议型 号：T2235产 地：美洲

  • T2251TAE684TAE684,NVP-TAE 684,

    NVP-TAE 684 is a excellently effective and specific ALK inhibitor(IC50=3 nM).

    价 格：￥电议型 号：T2251产 地：美洲

  • T2383PanobinostatPanobinostat,NVP-LBH589,LBH589

    Panobinostat is a potent inhibitor of all HDACs (Kis: 0.6-31 nM for HDAC1-11).

    价 格：￥电议型 号：T2383产 地：美洲

  • T2680NVP-BVU972NVP-BVU972

    NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.

    价 格：￥电议型 号：T2680产 地：美洲

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